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Histological variants of cutaneous Kaposi sarcoma.

Grayson W, Pantanowitz L - Diagn Pathol (2008)

Bottom Line: This review provides a comprehensive overview of the broad clinicopathologic spectrum of cutaneous Kaposi sarcoma (KS) lesions.Variants discussed include: usual KS lesions associated with disease progression (i.e. patch, plaque and nodular stage); morphologic subtypes alluded to in the older literature such as anaplastic and telangiectatic KS, as well as several lymphedematous variants; and numerous recently described variants including hyperkeratotic, keloidal, micronodular, pyogenic granuloma-like, ecchymotic, and intravascular KS.Involuting lesions as a result of treatment related regression are also presented.

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Affiliation: Histopathology Department, Ampath National Laboratory Support Services, Johannesburg, South Africa. wayne.grayson@live.com

ABSTRACT
This review provides a comprehensive overview of the broad clinicopathologic spectrum of cutaneous Kaposi sarcoma (KS) lesions. Variants discussed include: usual KS lesions associated with disease progression (i.e. patch, plaque and nodular stage); morphologic subtypes alluded to in the older literature such as anaplastic and telangiectatic KS, as well as several lymphedematous variants; and numerous recently described variants including hyperkeratotic, keloidal, micronodular, pyogenic granuloma-like, ecchymotic, and intravascular KS. Involuting lesions as a result of treatment related regression are also presented.

No MeSH data available.


Related in: MedlinePlus

Micronodular Kaposi sarcoma. A small, solid circumscribed spindle cell proliferation is present in the mid- to lower dermis (H&E stain).
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Figure 16: Micronodular Kaposi sarcoma. A small, solid circumscribed spindle cell proliferation is present in the mid- to lower dermis (H&E stain).

Mentions: Micronodular KS (Figure 16) is a recently described variant of nodular KS, which is characterized histologically by a small, unencapsulated, circumscribed spindle cell proliferation in the reticular dermis [47]. Although the paper by Kempf et al described micronodular cutaneous lesions in a patient with classic KS [47], similar lesions are occasionally encountered in the context of AIDS-associated KS, and are often removed in their entirety by a punch biopsy.


Histological variants of cutaneous Kaposi sarcoma.

Grayson W, Pantanowitz L - Diagn Pathol (2008)

Micronodular Kaposi sarcoma. A small, solid circumscribed spindle cell proliferation is present in the mid- to lower dermis (H&E stain).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2526984&req=5

Figure 16: Micronodular Kaposi sarcoma. A small, solid circumscribed spindle cell proliferation is present in the mid- to lower dermis (H&E stain).
Mentions: Micronodular KS (Figure 16) is a recently described variant of nodular KS, which is characterized histologically by a small, unencapsulated, circumscribed spindle cell proliferation in the reticular dermis [47]. Although the paper by Kempf et al described micronodular cutaneous lesions in a patient with classic KS [47], similar lesions are occasionally encountered in the context of AIDS-associated KS, and are often removed in their entirety by a punch biopsy.

Bottom Line: This review provides a comprehensive overview of the broad clinicopathologic spectrum of cutaneous Kaposi sarcoma (KS) lesions.Variants discussed include: usual KS lesions associated with disease progression (i.e. patch, plaque and nodular stage); morphologic subtypes alluded to in the older literature such as anaplastic and telangiectatic KS, as well as several lymphedematous variants; and numerous recently described variants including hyperkeratotic, keloidal, micronodular, pyogenic granuloma-like, ecchymotic, and intravascular KS.Involuting lesions as a result of treatment related regression are also presented.

View Article: PubMed Central - HTML - PubMed

Affiliation: Histopathology Department, Ampath National Laboratory Support Services, Johannesburg, South Africa. wayne.grayson@live.com

ABSTRACT
This review provides a comprehensive overview of the broad clinicopathologic spectrum of cutaneous Kaposi sarcoma (KS) lesions. Variants discussed include: usual KS lesions associated with disease progression (i.e. patch, plaque and nodular stage); morphologic subtypes alluded to in the older literature such as anaplastic and telangiectatic KS, as well as several lymphedematous variants; and numerous recently described variants including hyperkeratotic, keloidal, micronodular, pyogenic granuloma-like, ecchymotic, and intravascular KS. Involuting lesions as a result of treatment related regression are also presented.

No MeSH data available.


Related in: MedlinePlus