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Functional status of persons with chronic fatigue syndrome in the Wichita, Kansas, population.

Solomon L, Nisenbaum R, Reyes M, Papanicolaou DA, Reeves WC - Health Qual Life Outcomes (2003)

Bottom Line: Participants were asked about symptoms, medical and psychiatric illnesses, and about physical, social, and recreational functioning.Persons with chronic fatigue syndrome and other fatiguing illnesses had substantially less energy and spent less time on hobbies, schooling, or volunteer work than did non-fatigued controls (P <.01).Persons with chronic fatigue syndrome are as impaired as persons whose fatigue could be explained by a medical or psychiatric condition, and they have less energy than non-fatigued controls.

View Article: PubMed Central - HTML - PubMed

Affiliation: Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA. zfk9@cdc.gov

ABSTRACT

Background: Scant research has adequately addressed the impact of chronic fatigue syndrome on patients' daily activities and quality of life. Enumerating specific problems related to quality of life in chronic fatigue syndrome patients can help us to better understand and manage this illness. This study addresses issues of functional status in persons with chronic fatigue syndrome and other fatiguing illnesses in a population based sample, which can be generalized to all persons with chronic fatigue.

Methods: We conducted a random telephone survey in Wichita, Kansas to identify persons with chronic fatigue syndrome and other fatiguing illnesses. Respondents reporting severe fatigue of at least 1 month's duration and randomly selected non-fatigued respondents were asked to participate in a detailed telephone interview. Participants were asked about symptoms, medical and psychiatric illnesses, and about physical, social, and recreational functioning. Those meeting the 1994 chronic fatigue syndrome case definition, as determined on the basis of their telephone responses, were invited for clinical evaluation to confirm a diagnosis of chronic fatigue syndrome. For this analysis, we evaluated unemployment due to fatigue, number of hours per week spent on work, chores, and other activities (currently and prior to the onset of fatigue), and energy level.

Results: There was no difference between persons with chronic fatigue syndrome and persons with a chronic fatigue syndrome-like illness that could be explained by a medical or psychiatric condition for any of the outcomes we measured except for unemployment due to fatigue (15% vs. 40%, P <.01). Persons with chronic fatigue syndrome and other fatiguing illnesses had substantially less energy and spent less time on hobbies, schooling, or volunteer work than did non-fatigued controls (P <.01).

Conclusions: Persons with chronic fatigue syndrome are as impaired as persons whose fatigue could be explained by a medical or psychiatric condition, and they have less energy than non-fatigued controls.

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Related in: MedlinePlus

Study population as classified into fatigued and non-fatigued groups. *all CFS-like respondents who did not report an exclusionary condition were invited to participate in a clinical evaluation; †3 participants had inconclusive psychiatric assessments and could not be classified; Fatigue = severe fatigue of ≥ 1 month. Exclusion = subject reported a medical or psychiatric condition that would exclude a diagnosis of CFS. Prolonged Fatigue = severe fatigue ≥ 1 month but < 6 months. Chronic fatigue = severe fatigue ≥ 6 months, but without sufficient symptoms or fatigue severity to meet the 1994 CFS research case definition1. CFS-like = appears to meet the CFS case definition [1].Insufficient Fatigue = no longer reported sufficient symptoms or fatigue severity when evaluated clinically. Explained Syndromic Fatigue = appears to meet the CFS case definition, except that an exclusionary condition was either reported or discovered upon clinical evaluation.
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Figure 1: Study population as classified into fatigued and non-fatigued groups. *all CFS-like respondents who did not report an exclusionary condition were invited to participate in a clinical evaluation; †3 participants had inconclusive psychiatric assessments and could not be classified; Fatigue = severe fatigue of ≥ 1 month. Exclusion = subject reported a medical or psychiatric condition that would exclude a diagnosis of CFS. Prolonged Fatigue = severe fatigue ≥ 1 month but < 6 months. Chronic fatigue = severe fatigue ≥ 6 months, but without sufficient symptoms or fatigue severity to meet the 1994 CFS research case definition1. CFS-like = appears to meet the CFS case definition [1].Insufficient Fatigue = no longer reported sufficient symptoms or fatigue severity when evaluated clinically. Explained Syndromic Fatigue = appears to meet the CFS case definition, except that an exclusionary condition was either reported or discovered upon clinical evaluation.

Mentions: Figure 1 summarizes the composition of the fatigued and non-fatigued groups. The study population was mostly white (88%) and female (65%) and had a median age of 42 years. Demographic characteristics were similar across fatigue categories, with the exception of female sex and employment (data not shown). The percentage of women was lowest among the non-fatigued group without medical or psychiatric conditions (56%) and progressively increased with each level of fatigue, the CFS group having the highest percent of females (93%, test for trend P < .01). There was also a significant trend for employment. Employment was highest among the non-fatigued group (78%) and decreased with each level of fatigue, with only 54% of those with CFS being employed (test for trend P < .01). Unemployment due to fatigue is discussed below.


Functional status of persons with chronic fatigue syndrome in the Wichita, Kansas, population.

Solomon L, Nisenbaum R, Reyes M, Papanicolaou DA, Reeves WC - Health Qual Life Outcomes (2003)

Study population as classified into fatigued and non-fatigued groups. *all CFS-like respondents who did not report an exclusionary condition were invited to participate in a clinical evaluation; †3 participants had inconclusive psychiatric assessments and could not be classified; Fatigue = severe fatigue of ≥ 1 month. Exclusion = subject reported a medical or psychiatric condition that would exclude a diagnosis of CFS. Prolonged Fatigue = severe fatigue ≥ 1 month but < 6 months. Chronic fatigue = severe fatigue ≥ 6 months, but without sufficient symptoms or fatigue severity to meet the 1994 CFS research case definition1. CFS-like = appears to meet the CFS case definition [1].Insufficient Fatigue = no longer reported sufficient symptoms or fatigue severity when evaluated clinically. Explained Syndromic Fatigue = appears to meet the CFS case definition, except that an exclusionary condition was either reported or discovered upon clinical evaluation.
© Copyright Policy
Related In: Results  -  Collection

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getmorefigures.php?uid=PMC239865&req=5

Figure 1: Study population as classified into fatigued and non-fatigued groups. *all CFS-like respondents who did not report an exclusionary condition were invited to participate in a clinical evaluation; †3 participants had inconclusive psychiatric assessments and could not be classified; Fatigue = severe fatigue of ≥ 1 month. Exclusion = subject reported a medical or psychiatric condition that would exclude a diagnosis of CFS. Prolonged Fatigue = severe fatigue ≥ 1 month but < 6 months. Chronic fatigue = severe fatigue ≥ 6 months, but without sufficient symptoms or fatigue severity to meet the 1994 CFS research case definition1. CFS-like = appears to meet the CFS case definition [1].Insufficient Fatigue = no longer reported sufficient symptoms or fatigue severity when evaluated clinically. Explained Syndromic Fatigue = appears to meet the CFS case definition, except that an exclusionary condition was either reported or discovered upon clinical evaluation.
Mentions: Figure 1 summarizes the composition of the fatigued and non-fatigued groups. The study population was mostly white (88%) and female (65%) and had a median age of 42 years. Demographic characteristics were similar across fatigue categories, with the exception of female sex and employment (data not shown). The percentage of women was lowest among the non-fatigued group without medical or psychiatric conditions (56%) and progressively increased with each level of fatigue, the CFS group having the highest percent of females (93%, test for trend P < .01). There was also a significant trend for employment. Employment was highest among the non-fatigued group (78%) and decreased with each level of fatigue, with only 54% of those with CFS being employed (test for trend P < .01). Unemployment due to fatigue is discussed below.

Bottom Line: Participants were asked about symptoms, medical and psychiatric illnesses, and about physical, social, and recreational functioning.Persons with chronic fatigue syndrome and other fatiguing illnesses had substantially less energy and spent less time on hobbies, schooling, or volunteer work than did non-fatigued controls (P <.01).Persons with chronic fatigue syndrome are as impaired as persons whose fatigue could be explained by a medical or psychiatric condition, and they have less energy than non-fatigued controls.

View Article: PubMed Central - HTML - PubMed

Affiliation: Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA. zfk9@cdc.gov

ABSTRACT

Background: Scant research has adequately addressed the impact of chronic fatigue syndrome on patients' daily activities and quality of life. Enumerating specific problems related to quality of life in chronic fatigue syndrome patients can help us to better understand and manage this illness. This study addresses issues of functional status in persons with chronic fatigue syndrome and other fatiguing illnesses in a population based sample, which can be generalized to all persons with chronic fatigue.

Methods: We conducted a random telephone survey in Wichita, Kansas to identify persons with chronic fatigue syndrome and other fatiguing illnesses. Respondents reporting severe fatigue of at least 1 month's duration and randomly selected non-fatigued respondents were asked to participate in a detailed telephone interview. Participants were asked about symptoms, medical and psychiatric illnesses, and about physical, social, and recreational functioning. Those meeting the 1994 chronic fatigue syndrome case definition, as determined on the basis of their telephone responses, were invited for clinical evaluation to confirm a diagnosis of chronic fatigue syndrome. For this analysis, we evaluated unemployment due to fatigue, number of hours per week spent on work, chores, and other activities (currently and prior to the onset of fatigue), and energy level.

Results: There was no difference between persons with chronic fatigue syndrome and persons with a chronic fatigue syndrome-like illness that could be explained by a medical or psychiatric condition for any of the outcomes we measured except for unemployment due to fatigue (15% vs. 40%, P <.01). Persons with chronic fatigue syndrome and other fatiguing illnesses had substantially less energy and spent less time on hobbies, schooling, or volunteer work than did non-fatigued controls (P <.01).

Conclusions: Persons with chronic fatigue syndrome are as impaired as persons whose fatigue could be explained by a medical or psychiatric condition, and they have less energy than non-fatigued controls.

Show MeSH
Related in: MedlinePlus