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Solitary colonic polypoid ganglioneuroma.

Mendez IM, Pereda T, Rodriguez FJ, Funez R, Sanchez A - Diagn Pathol (2008)

Bottom Line: This short report discusses a case of solitary colonic polypoid ganglioneuroma associated with melanosis coli in a woman with no systemic manifestations.The nature and significance of this event remains unclear, although this may be coincidental due to the laxative intake.Further investigation is necessary to clarify this point.

View Article: PubMed Central - HTML - PubMed

Affiliation: Service of Gastroenterology, Hospital Costa de Sol, Marbella, Malaga, Spain. chabeli_estepona@hotmail.com

ABSTRACT
This short report discusses a case of solitary colonic polypoid ganglioneuroma associated with melanosis coli in a woman with no systemic manifestations. To our knowledge this is the first ganglioneuroma reported in the literature in association with melanosis coli. The nature and significance of this event remains unclear, although this may be coincidental due to the laxative intake. Further investigation is necessary to clarify this point. The interest of this case lies moreover in the rarity of this entity and its endoscopic and histologic resemblance to sessile polyps frequent in the clinical practice.

No MeSH data available.


Related in: MedlinePlus

Endoscopic image of the polyp.
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Figure 1: Endoscopic image of the polyp.

Mentions: A 48-year old woman with arthrosis underwent colonoscopy because of a family history of colon cancer (father and cousin) and an episode of lower intestinal bleeding. The patient was an anthracene-type laxatives ("sacred rind") consumer due to usual constipation. No other symptoms were related. She and her family had no known history of multiple endrocrine neoplasia or neurofibromatosis. The laboratory tests were within the normal limits, including carcinoembryonic antigen (CEA). Physical examination revealed an anal fissure. No pigmented skin lesions were identified. The colonoscopy revealed a millimetric sessile polyp in the sigmoid colon that was removed with biopsy forceps (Figure 1).


Solitary colonic polypoid ganglioneuroma.

Mendez IM, Pereda T, Rodriguez FJ, Funez R, Sanchez A - Diagn Pathol (2008)

Endoscopic image of the polyp.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2390510&req=5

Figure 1: Endoscopic image of the polyp.
Mentions: A 48-year old woman with arthrosis underwent colonoscopy because of a family history of colon cancer (father and cousin) and an episode of lower intestinal bleeding. The patient was an anthracene-type laxatives ("sacred rind") consumer due to usual constipation. No other symptoms were related. She and her family had no known history of multiple endrocrine neoplasia or neurofibromatosis. The laboratory tests were within the normal limits, including carcinoembryonic antigen (CEA). Physical examination revealed an anal fissure. No pigmented skin lesions were identified. The colonoscopy revealed a millimetric sessile polyp in the sigmoid colon that was removed with biopsy forceps (Figure 1).

Bottom Line: This short report discusses a case of solitary colonic polypoid ganglioneuroma associated with melanosis coli in a woman with no systemic manifestations.The nature and significance of this event remains unclear, although this may be coincidental due to the laxative intake.Further investigation is necessary to clarify this point.

View Article: PubMed Central - HTML - PubMed

Affiliation: Service of Gastroenterology, Hospital Costa de Sol, Marbella, Malaga, Spain. chabeli_estepona@hotmail.com

ABSTRACT
This short report discusses a case of solitary colonic polypoid ganglioneuroma associated with melanosis coli in a woman with no systemic manifestations. To our knowledge this is the first ganglioneuroma reported in the literature in association with melanosis coli. The nature and significance of this event remains unclear, although this may be coincidental due to the laxative intake. Further investigation is necessary to clarify this point. The interest of this case lies moreover in the rarity of this entity and its endoscopic and histologic resemblance to sessile polyps frequent in the clinical practice.

No MeSH data available.


Related in: MedlinePlus