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Detection of inflammatory bowel disease: diagnostic performance of cross-sectional imaging modalities.

Horsthuis K, Stokkers PC, Stoker J - Abdom Imaging (2008 Jul-Aug)

Bottom Line: Different cross-sectional imaging techniques can be used as a diagnostic tool for the evaluation of inflammatory bowel disease (IBD).In this report the diagnostic performances of ultrasonography, magnetic resonance imaging and computed tomography in the detection of IBD and the evaluation of known IBD are described, together with a short update on patient preparation and imaging technique of the respective modalities discussed.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology, Academic Medical Center, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands. k.horsthuis@amc.uva.nl

ABSTRACT
Different cross-sectional imaging techniques can be used as a diagnostic tool for the evaluation of inflammatory bowel disease (IBD). In this report the diagnostic performances of ultrasonography, magnetic resonance imaging and computed tomography in the detection of IBD and the evaluation of known IBD are described, together with a short update on patient preparation and imaging technique of the respective modalities discussed.

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A 12-year-old male patient with known CD who underwent MR-enterography for the evaluation of the small bowel (same patient depicted in Fig. 6b). Axial T1-weighted image shows pathological enhancement of thickened small-bowel loops after administration of intravenous contrast medium (arrowheads). Approximately, 1 m of small bowel (terminal jejunum, proximal ileum) was shown to be affected.
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Fig8: A 12-year-old male patient with known CD who underwent MR-enterography for the evaluation of the small bowel (same patient depicted in Fig. 6b). Axial T1-weighted image shows pathological enhancement of thickened small-bowel loops after administration of intravenous contrast medium (arrowheads). Approximately, 1 m of small bowel (terminal jejunum, proximal ileum) was shown to be affected.

Mentions: A bowel wall thickness exceeding 3 mm should be considered as an indicative of disease. Besides bowel wall thickening the most important criterion indicative of active IBD is pathological bowel wall enhancement after the administration of intravenous gadolinium. Bowel wall enhancement can always be seen as the bowel is a highly vascularized structure. However, in active IBD increased enhancement can be observed, due to the increased vascularization and the increased capillary leakage of the affected tissue (Fig. 8). In CD it has been hypothesized that the degree of enhancement correlates with the degree of disease severity, but this statement has not been extensively corroborated [50–53].Fig. 8.


Detection of inflammatory bowel disease: diagnostic performance of cross-sectional imaging modalities.

Horsthuis K, Stokkers PC, Stoker J - Abdom Imaging (2008 Jul-Aug)

A 12-year-old male patient with known CD who underwent MR-enterography for the evaluation of the small bowel (same patient depicted in Fig. 6b). Axial T1-weighted image shows pathological enhancement of thickened small-bowel loops after administration of intravenous contrast medium (arrowheads). Approximately, 1 m of small bowel (terminal jejunum, proximal ileum) was shown to be affected.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2386533&req=5

Fig8: A 12-year-old male patient with known CD who underwent MR-enterography for the evaluation of the small bowel (same patient depicted in Fig. 6b). Axial T1-weighted image shows pathological enhancement of thickened small-bowel loops after administration of intravenous contrast medium (arrowheads). Approximately, 1 m of small bowel (terminal jejunum, proximal ileum) was shown to be affected.
Mentions: A bowel wall thickness exceeding 3 mm should be considered as an indicative of disease. Besides bowel wall thickening the most important criterion indicative of active IBD is pathological bowel wall enhancement after the administration of intravenous gadolinium. Bowel wall enhancement can always be seen as the bowel is a highly vascularized structure. However, in active IBD increased enhancement can be observed, due to the increased vascularization and the increased capillary leakage of the affected tissue (Fig. 8). In CD it has been hypothesized that the degree of enhancement correlates with the degree of disease severity, but this statement has not been extensively corroborated [50–53].Fig. 8.

Bottom Line: Different cross-sectional imaging techniques can be used as a diagnostic tool for the evaluation of inflammatory bowel disease (IBD).In this report the diagnostic performances of ultrasonography, magnetic resonance imaging and computed tomography in the detection of IBD and the evaluation of known IBD are described, together with a short update on patient preparation and imaging technique of the respective modalities discussed.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology, Academic Medical Center, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands. k.horsthuis@amc.uva.nl

ABSTRACT
Different cross-sectional imaging techniques can be used as a diagnostic tool for the evaluation of inflammatory bowel disease (IBD). In this report the diagnostic performances of ultrasonography, magnetic resonance imaging and computed tomography in the detection of IBD and the evaluation of known IBD are described, together with a short update on patient preparation and imaging technique of the respective modalities discussed.

Show MeSH
Related in: MedlinePlus