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A randomised controlled trial of breast cancer genetics services in South East Scotland: psychological impact.

Fry A, Cull A, Appleton S, Rush R, Holloway S, Gorman D, Cetnarskyj R, Thomas R, Campbell J, Anderson E, Steel M, Porteous M, Campbell H - Br. J. Cancer (2003)

Bottom Line: One hundred and seventy general practices were randomised to refer patients to the existing standard regional service or the novel community-based service.Participants completed postal questionnaires at baseline (n=373), 4 weeks (n=276) and 6 months (n=263) to assess perceived risk of breast cancer, subjective and objective understanding of genetics and screening issues, general psychological distress, cancer worry and health behaviours.Therefore, decisions regarding the implementation of the novel community-based service should be based on the resources required and client satisfaction with the service.

View Article: PubMed Central - PubMed

Affiliation: Cancer Research UK, Edinburgh Oncology Unit, Western General Hospital, Crewe Road South, Edinburgh EH4 2XR, UK.

ABSTRACT
This study compared the psychological impact of two models of breast cancer genetics services in South East Scotland. One hundred and seventy general practices were randomised to refer patients to the existing standard regional service or the novel community-based service. Participants completed postal questionnaires at baseline (n=373), 4 weeks (n=276) and 6 months (n=263) to assess perceived risk of breast cancer, subjective and objective understanding of genetics and screening issues, general psychological distress, cancer worry and health behaviours. For participants in both arms of the trial, there were improvements in subjective and objective understanding up to 4 weeks which were generally sustained up to 6 months. However, improvements in subjective understanding for the women at low risk of breast cancer (i.e. not at significantly increased risk) in the standard service arm did not reach statistical significance. Cancer worry was significantly reduced at 6 months for participants in both arms of the trial. The two models of cancer genetics services tested were generally comparable in terms of the participants' psychological outcomes. Therefore, decisions regarding the implementation of the novel community-based service should be based on the resources required and client satisfaction with the service.

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Related in: MedlinePlus

Progress of participants through the trial. a For example, the women had received genetic counselling elsewhere or had been treated for cancer. b For example investigation of breast symptoms. c Includes nine women who were excluded at the 4 week assessment due to administrative reasons (n=5) or nonreturn of the questionnaire (n=4). d Includes 10 women who were excluded at the 4 week assessment due to administrative reasons (n=4) or nonreturn of the questionnaire (n=6).
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Related In: Results  -  Collection


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fig1: Progress of participants through the trial. a For example, the women had received genetic counselling elsewhere or had been treated for cancer. b For example investigation of breast symptoms. c Includes nine women who were excluded at the 4 week assessment due to administrative reasons (n=5) or nonreturn of the questionnaire (n=4). d Includes 10 women who were excluded at the 4 week assessment due to administrative reasons (n=4) or nonreturn of the questionnaire (n=6).

Mentions: Figure 1Figure 1


A randomised controlled trial of breast cancer genetics services in South East Scotland: psychological impact.

Fry A, Cull A, Appleton S, Rush R, Holloway S, Gorman D, Cetnarskyj R, Thomas R, Campbell J, Anderson E, Steel M, Porteous M, Campbell H - Br. J. Cancer (2003)

Progress of participants through the trial. a For example, the women had received genetic counselling elsewhere or had been treated for cancer. b For example investigation of breast symptoms. c Includes nine women who were excluded at the 4 week assessment due to administrative reasons (n=5) or nonreturn of the questionnaire (n=4). d Includes 10 women who were excluded at the 4 week assessment due to administrative reasons (n=4) or nonreturn of the questionnaire (n=6).
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2376929&req=5

fig1: Progress of participants through the trial. a For example, the women had received genetic counselling elsewhere or had been treated for cancer. b For example investigation of breast symptoms. c Includes nine women who were excluded at the 4 week assessment due to administrative reasons (n=5) or nonreturn of the questionnaire (n=4). d Includes 10 women who were excluded at the 4 week assessment due to administrative reasons (n=4) or nonreturn of the questionnaire (n=6).
Mentions: Figure 1Figure 1

Bottom Line: One hundred and seventy general practices were randomised to refer patients to the existing standard regional service or the novel community-based service.Participants completed postal questionnaires at baseline (n=373), 4 weeks (n=276) and 6 months (n=263) to assess perceived risk of breast cancer, subjective and objective understanding of genetics and screening issues, general psychological distress, cancer worry and health behaviours.Therefore, decisions regarding the implementation of the novel community-based service should be based on the resources required and client satisfaction with the service.

View Article: PubMed Central - PubMed

Affiliation: Cancer Research UK, Edinburgh Oncology Unit, Western General Hospital, Crewe Road South, Edinburgh EH4 2XR, UK.

ABSTRACT
This study compared the psychological impact of two models of breast cancer genetics services in South East Scotland. One hundred and seventy general practices were randomised to refer patients to the existing standard regional service or the novel community-based service. Participants completed postal questionnaires at baseline (n=373), 4 weeks (n=276) and 6 months (n=263) to assess perceived risk of breast cancer, subjective and objective understanding of genetics and screening issues, general psychological distress, cancer worry and health behaviours. For participants in both arms of the trial, there were improvements in subjective and objective understanding up to 4 weeks which were generally sustained up to 6 months. However, improvements in subjective understanding for the women at low risk of breast cancer (i.e. not at significantly increased risk) in the standard service arm did not reach statistical significance. Cancer worry was significantly reduced at 6 months for participants in both arms of the trial. The two models of cancer genetics services tested were generally comparable in terms of the participants' psychological outcomes. Therefore, decisions regarding the implementation of the novel community-based service should be based on the resources required and client satisfaction with the service.

Show MeSH
Related in: MedlinePlus