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Intense inflammation in bladder carcinoma is associated with angiogenesis and indicates good prognosis.

Offersen BV, Knap MM, Marcussen N, Horsman MR, Hamilton-Dutoit S, Overgaard J - Br. J. Cancer (2002)

Bottom Line: Areas of minimal, moderate and intense inflammation were found in 48, 92 and 32 tumours.High microvessel density, irrespective of the degree of inflammation, was associated with a significantly better disease-specific survival (P=0.01).In conclusion, inflammation was significantly correlated to microvessel density, and areas of intense inflammation were an independent marker of good prognosis.

View Article: PubMed Central - PubMed

Affiliation: Department of Experimental Clinical Oncology, Danish Cancer Society, Aarhus University Hospital, Noerrebrogade 44, bldg 5, DK-8000 Aarhus C, Denmark. bvo@oncology.dk

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Distribution of MVD evaluated in areas of different degrees of inflammation. Inflammation group 1 was ‘minimal inflammation’, group 2 was ‘moderate inflammation’, and group 3 was ‘intense inflammation’.
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fig5: Distribution of MVD evaluated in areas of different degrees of inflammation. Inflammation group 1 was ‘minimal inflammation’, group 2 was ‘moderate inflammation’, and group 3 was ‘intense inflammation’.

Mentions: The median value of MVD1 was 32 (range, 7–100), median MVD2 was 63 (range, 21–217), and median MVD3 was 105 (range, 32–249) (Figure 5Figure 5


Intense inflammation in bladder carcinoma is associated with angiogenesis and indicates good prognosis.

Offersen BV, Knap MM, Marcussen N, Horsman MR, Hamilton-Dutoit S, Overgaard J - Br. J. Cancer (2002)

Distribution of MVD evaluated in areas of different degrees of inflammation. Inflammation group 1 was ‘minimal inflammation’, group 2 was ‘moderate inflammation’, and group 3 was ‘intense inflammation’.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2376289&req=5

fig5: Distribution of MVD evaluated in areas of different degrees of inflammation. Inflammation group 1 was ‘minimal inflammation’, group 2 was ‘moderate inflammation’, and group 3 was ‘intense inflammation’.
Mentions: The median value of MVD1 was 32 (range, 7–100), median MVD2 was 63 (range, 21–217), and median MVD3 was 105 (range, 32–249) (Figure 5Figure 5

Bottom Line: Areas of minimal, moderate and intense inflammation were found in 48, 92 and 32 tumours.High microvessel density, irrespective of the degree of inflammation, was associated with a significantly better disease-specific survival (P=0.01).In conclusion, inflammation was significantly correlated to microvessel density, and areas of intense inflammation were an independent marker of good prognosis.

View Article: PubMed Central - PubMed

Affiliation: Department of Experimental Clinical Oncology, Danish Cancer Society, Aarhus University Hospital, Noerrebrogade 44, bldg 5, DK-8000 Aarhus C, Denmark. bvo@oncology.dk

Show MeSH
Related in: MedlinePlus