Nephrotoxicity in survivors of Wilms' tumours in the North of England.
Bottom Line: Thirty-seven patients achieved maximal urine osmolalities > or =800 mOsm kg(-1), but three failed to achieve this value even after DDAVP administration.Two patients had evidence of increased urinary albumin excretion.Compensatory renal hypertrophy was seen in all but two patients, but blood pressure was within normal limits in all patients.
Affiliation: Department of Child Health, University of Newcastle upon Tyne, Newcastle upon Tyne NE1 4LP, UK. email@example.comShow MeSH
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Mentions: Glomerular filtration rate was measured in all 40 patients with a median of 100 ml min−1 1.73 m−2 (range 61–150). Nine patients had a GFR below the reference range for healthy individuals with two kidneys (>90 ml min−1 1.73 m−2), and four had a GFR below 80 ml min−1 1.73 m−2 (Figure 1Figure 1
Affiliation: Department of Child Health, University of Newcastle upon Tyne, Newcastle upon Tyne NE1 4LP, UK. firstname.lastname@example.org