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Choroid plexus tumours.

Wolff JE, Sajedi M, Brant R, Coppes MJ, Egeler RM - Br. J. Cancer (2002)

Bottom Line: Histology was the most important prognostic factor, as one, five, and 10-year projected survival rates were 90, 81, and 77% in choroid plexus-papilloma (n=353) compared to only 71, 41, and 35% in choroid plexus-carcinoma respectively (P<0.0005).Radiotherapy was associated with significantly better survival in choroid plexus-carcinomas.This should be followed by adjuvant treatment in case of choroid plexus-carcinoma, and a "wait and see" approach in choroid plexus-papilloma.

View Article: PubMed Central - PubMed

Affiliation: Department of Pediatric Oncology, Alberta Children's Hospital, 1820 Richmond Road SW, Calgary, Alberta, Canada T2T 5C7. johannes.wolff@barmherzige-regensburg.de

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Age distribution of choroid plexus tumours: Supratentorial tumours occur most frequently in infants (A) n=188, while the age distribution of infratentorial tumours is spread over all ages (B), n=71; P<0.005, Mann–Whitney U-test). This analysis included only patients with documented primary intracerebral locations.
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fig1: Age distribution of choroid plexus tumours: Supratentorial tumours occur most frequently in infants (A) n=188, while the age distribution of infratentorial tumours is spread over all ages (B), n=71; P<0.005, Mann–Whitney U-test). This analysis included only patients with documented primary intracerebral locations.

Mentions: Gender, age at diagnosis, location, histology and metastases could be correlated to each other regardless if treatment or observation time data were sufficient. Surprisingly, none of these parameters was distributed homogeneously among groups defined by the others. In the total group, the male : female ratio was 1.2 : 1. Relating gender to location showed relatively more female patients with tumours located in the cerebellopontine angle (CPA, 29 observed, 20 expected). Age at diagnosis covered a large range from 0 years (foetus) to 72 years, but most of the patients were children, resulting in a median age at diagnosis of 3.5 years in the whole database. The most striking inhomogeneity was found when relating age to location (Figure 1Figure 1


Choroid plexus tumours.

Wolff JE, Sajedi M, Brant R, Coppes MJ, Egeler RM - Br. J. Cancer (2002)

Age distribution of choroid plexus tumours: Supratentorial tumours occur most frequently in infants (A) n=188, while the age distribution of infratentorial tumours is spread over all ages (B), n=71; P<0.005, Mann–Whitney U-test). This analysis included only patients with documented primary intracerebral locations.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2376189&req=5

fig1: Age distribution of choroid plexus tumours: Supratentorial tumours occur most frequently in infants (A) n=188, while the age distribution of infratentorial tumours is spread over all ages (B), n=71; P<0.005, Mann–Whitney U-test). This analysis included only patients with documented primary intracerebral locations.
Mentions: Gender, age at diagnosis, location, histology and metastases could be correlated to each other regardless if treatment or observation time data were sufficient. Surprisingly, none of these parameters was distributed homogeneously among groups defined by the others. In the total group, the male : female ratio was 1.2 : 1. Relating gender to location showed relatively more female patients with tumours located in the cerebellopontine angle (CPA, 29 observed, 20 expected). Age at diagnosis covered a large range from 0 years (foetus) to 72 years, but most of the patients were children, resulting in a median age at diagnosis of 3.5 years in the whole database. The most striking inhomogeneity was found when relating age to location (Figure 1Figure 1

Bottom Line: Histology was the most important prognostic factor, as one, five, and 10-year projected survival rates were 90, 81, and 77% in choroid plexus-papilloma (n=353) compared to only 71, 41, and 35% in choroid plexus-carcinoma respectively (P<0.0005).Radiotherapy was associated with significantly better survival in choroid plexus-carcinomas.This should be followed by adjuvant treatment in case of choroid plexus-carcinoma, and a "wait and see" approach in choroid plexus-papilloma.

View Article: PubMed Central - PubMed

Affiliation: Department of Pediatric Oncology, Alberta Children's Hospital, 1820 Richmond Road SW, Calgary, Alberta, Canada T2T 5C7. johannes.wolff@barmherzige-regensburg.de

Show MeSH
Related in: MedlinePlus