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survivin messenger RNA expression is a good prognostic biomarker for oesophageal carcinoma.

Ikeguchi M, Kaibara N - Br. J. Cancer (2002)

Bottom Line: Expression levels of survivin and glyceraldehyde-3-phosphate dehydrogenase mRNA were analysed quantitatively by real-time reverse transcriptase polymerase chain reaction (RT-PCR).Tumour-survivin/glyceraldehyde-3-phosphate dehydrogenase ratio did not correlate with histologic type, lymph node metastasis, and stage of tumours.In these patients, tumour-survivin mRNA expression was recognised as a good marker of cancer recurrence independently from tumour stage.

View Article: PubMed Central - PubMed

Affiliation: First Department of Surgery, Faculty of Medicine, Tottori University, 36-1 Nishi-cho, Yonago 683-8504, Japan. masaike@grape.med.tottori-u.ac.jp

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Related in: MedlinePlus

Strong survivin protein expression was detected in nuclei of all cancer cells and weak survivin expression was observed in the cytoplasm by immunostaining with a polyclonal antibody (×100).
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fig3: Strong survivin protein expression was detected in nuclei of all cancer cells and weak survivin expression was observed in the cytoplasm by immunostaining with a polyclonal antibody (×100).

Mentions: Survivin protein was detected not only in the cytoplasm, but also in nuclei of all cancer cells (Figure 3Figure 3


survivin messenger RNA expression is a good prognostic biomarker for oesophageal carcinoma.

Ikeguchi M, Kaibara N - Br. J. Cancer (2002)

Strong survivin protein expression was detected in nuclei of all cancer cells and weak survivin expression was observed in the cytoplasm by immunostaining with a polyclonal antibody (×100).
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2376173&req=5

fig3: Strong survivin protein expression was detected in nuclei of all cancer cells and weak survivin expression was observed in the cytoplasm by immunostaining with a polyclonal antibody (×100).
Mentions: Survivin protein was detected not only in the cytoplasm, but also in nuclei of all cancer cells (Figure 3Figure 3

Bottom Line: Expression levels of survivin and glyceraldehyde-3-phosphate dehydrogenase mRNA were analysed quantitatively by real-time reverse transcriptase polymerase chain reaction (RT-PCR).Tumour-survivin/glyceraldehyde-3-phosphate dehydrogenase ratio did not correlate with histologic type, lymph node metastasis, and stage of tumours.In these patients, tumour-survivin mRNA expression was recognised as a good marker of cancer recurrence independently from tumour stage.

View Article: PubMed Central - PubMed

Affiliation: First Department of Surgery, Faculty of Medicine, Tottori University, 36-1 Nishi-cho, Yonago 683-8504, Japan. masaike@grape.med.tottori-u.ac.jp

Show MeSH
Related in: MedlinePlus