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Influence of pathological tumour variables on long-term survival in resectable gastric cancer.

Cuschieri A, Talbot IC, Weeden S, MRC Upper GI Cancer Working Par - Br. J. Cancer (2002)

Bottom Line: In the multivariate analysis, UICC clinical stage and eosinophilic infiltration were found to have a significant influence.Risk of death increased for UICC stage II and III patients (Hazard Ratio for stage II compared to stage I=2.0, 95% Confidence Interval (CI) 1.4-2.9; Hazard Ratio for stage III compared to stage I=3.5, 95% CI 2.5-4.8).This association between survival and eosinophilic infiltration merits further study.

View Article: PubMed Central - PubMed

Affiliation: Department of Surgery and Molecular Oncology, Ninewells Hospital and Medical School, University of Dundee, Dundee DD1 9SY, UK. a.cuschieri@dundee.ac.uk

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Survival by eosinophil level (stages I–III).
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fig3: Survival by eosinophil level (stages I–III).

Mentions: Hazard ratios, with 95% confidence intervals, for the significant variables are tabulated in Table 4Table 4Hazard ratios for significant variables in the multivariate model. Stage II patients have double the risk of death as stage I patients, and for stage III patients the risk is increased to 3.5 times that for stage I. A high level of eosinophils was associated with less than half the risk of death of those who have no eosinophils, however it should be noted that the group of patients with a high level of eosinophils is very small. The association between improved survival and a high eosinophil count is repeated for all stages, as can be seen in Figure 3Figure 3


Influence of pathological tumour variables on long-term survival in resectable gastric cancer.

Cuschieri A, Talbot IC, Weeden S, MRC Upper GI Cancer Working Par - Br. J. Cancer (2002)

Survival by eosinophil level (stages I–III).
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2375301&req=5

fig3: Survival by eosinophil level (stages I–III).
Mentions: Hazard ratios, with 95% confidence intervals, for the significant variables are tabulated in Table 4Table 4Hazard ratios for significant variables in the multivariate model. Stage II patients have double the risk of death as stage I patients, and for stage III patients the risk is increased to 3.5 times that for stage I. A high level of eosinophils was associated with less than half the risk of death of those who have no eosinophils, however it should be noted that the group of patients with a high level of eosinophils is very small. The association between improved survival and a high eosinophil count is repeated for all stages, as can be seen in Figure 3Figure 3

Bottom Line: In the multivariate analysis, UICC clinical stage and eosinophilic infiltration were found to have a significant influence.Risk of death increased for UICC stage II and III patients (Hazard Ratio for stage II compared to stage I=2.0, 95% Confidence Interval (CI) 1.4-2.9; Hazard Ratio for stage III compared to stage I=3.5, 95% CI 2.5-4.8).This association between survival and eosinophilic infiltration merits further study.

View Article: PubMed Central - PubMed

Affiliation: Department of Surgery and Molecular Oncology, Ninewells Hospital and Medical School, University of Dundee, Dundee DD1 9SY, UK. a.cuschieri@dundee.ac.uk

Show MeSH
Related in: MedlinePlus