Influence of pathological tumour variables on long-term survival in resectable gastric cancer.
Bottom Line: In the multivariate analysis, UICC clinical stage and eosinophilic infiltration were found to have a significant influence.Risk of death increased for UICC stage II and III patients (Hazard Ratio for stage II compared to stage I=2.0, 95% Confidence Interval (CI) 1.4-2.9; Hazard Ratio for stage III compared to stage I=3.5, 95% CI 2.5-4.8).This association between survival and eosinophilic infiltration merits further study.
Affiliation: Department of Surgery and Molecular Oncology, Ninewells Hospital and Medical School, University of Dundee, Dundee DD1 9SY, UK. email@example.comShow MeSH
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Mentions: Hazard ratios, with 95% confidence intervals, for the significant variables are tabulated in Table 4Table 4Hazard ratios for significant variables in the multivariate model. Stage II patients have double the risk of death as stage I patients, and for stage III patients the risk is increased to 3.5 times that for stage I. A high level of eosinophils was associated with less than half the risk of death of those who have no eosinophils, however it should be noted that the group of patients with a high level of eosinophils is very small. The association between improved survival and a high eosinophil count is repeated for all stages, as can be seen in Figure 3Figure 3
Affiliation: Department of Surgery and Molecular Oncology, Ninewells Hospital and Medical School, University of Dundee, Dundee DD1 9SY, UK. firstname.lastname@example.org