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Muscle UCP-3 mRNA levels are elevated in weight loss associated with gastrointestinal adenocarcinoma in humans.

Collins P, Bing C, McCulloch P, Williams G - Br. J. Cancer (2002)

Bottom Line: The mitochondrial uncoupling proteins-2 and -3 are putative mediators of thermogenesis and energy expenditure.Uncoupling proteins-2 mRNA levels did not differ significantly between groups.Elevations in muscle uncoupling proteins-3 activity may enhance energy expenditure and this in turn could contribute to tissue catabolism.

View Article: PubMed Central - PubMed

Affiliation: Gastroenterology Unit, University Hospital Aintree, Longmoor Lane, Liverpool L9 7AL, UK. petecolins@aol.com

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Related in: MedlinePlus

Mean UCP-2 and UCP-3 levels for the studied groups. Data is expressed as a ratio: optical density (OD) UCP-2 or -3 to OD of HPRT ±s.e.m.
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fig1: Mean UCP-2 and UCP-3 levels for the studied groups. Data is expressed as a ratio: optical density (OD) UCP-2 or -3 to OD of HPRT ±s.e.m.

Mentions: Table 2Table 2UCP-2 and -3 mRNA expression for each of the studied groups. Data is expressed as a ratio: optical density (OD) UCP-2 or -3 to OD of HPRT shows the levels of UCP-2 and -3 mRNA, expressed as ratios to HPRT mRNA; these data are expressed graphically in Figure 1Figure 1


Muscle UCP-3 mRNA levels are elevated in weight loss associated with gastrointestinal adenocarcinoma in humans.

Collins P, Bing C, McCulloch P, Williams G - Br. J. Cancer (2002)

Mean UCP-2 and UCP-3 levels for the studied groups. Data is expressed as a ratio: optical density (OD) UCP-2 or -3 to OD of HPRT ±s.e.m.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2375209&req=5

fig1: Mean UCP-2 and UCP-3 levels for the studied groups. Data is expressed as a ratio: optical density (OD) UCP-2 or -3 to OD of HPRT ±s.e.m.
Mentions: Table 2Table 2UCP-2 and -3 mRNA expression for each of the studied groups. Data is expressed as a ratio: optical density (OD) UCP-2 or -3 to OD of HPRT shows the levels of UCP-2 and -3 mRNA, expressed as ratios to HPRT mRNA; these data are expressed graphically in Figure 1Figure 1

Bottom Line: The mitochondrial uncoupling proteins-2 and -3 are putative mediators of thermogenesis and energy expenditure.Uncoupling proteins-2 mRNA levels did not differ significantly between groups.Elevations in muscle uncoupling proteins-3 activity may enhance energy expenditure and this in turn could contribute to tissue catabolism.

View Article: PubMed Central - PubMed

Affiliation: Gastroenterology Unit, University Hospital Aintree, Longmoor Lane, Liverpool L9 7AL, UK. petecolins@aol.com

Show MeSH
Related in: MedlinePlus