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Occult axillary lymph node metastases are of no prognostic significance in breast cancer.

Millis RR, Springall R, Lee AH, Ryder K, Rytina ER, Fentiman IS - Br. J. Cancer (2002)

Bottom Line: The median follow-up was 18.9 years with 153 breast cancer related deaths.Multivariate analysis, however, showed that survival was related to tumour size and histological grade.We believe that the current evidence does not support the routine use of serial sections or immunohistochemistry for the detection of occult metastases in the management of lymph node negative patients, but that the traditional factors of histological grade and tumour size are useful.

View Article: PubMed Central - PubMed

Affiliation: Hedley Atkins ICRF Breast Pathology Laboratory, Guy's Hospital, London SE1 9RT, UK.

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Overall survival is not related to the size of the largest axillary nodal metastasis in patients with occult metastasis or single node positive, χ2=0.52, P=0.91. Metastasis size was divided using cut-offs of 0.2, 2 and 10 mm.
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fig2: Overall survival is not related to the size of the largest axillary nodal metastasis in patients with occult metastasis or single node positive, χ2=0.52, P=0.91. Metastasis size was divided using cut-offs of 0.2, 2 and 10 mm.

Mentions: Survival was not related to either the area or the largest diameter of the metastasis in the one-node positive and occult metastasis patients (Figure 2Figure 2


Occult axillary lymph node metastases are of no prognostic significance in breast cancer.

Millis RR, Springall R, Lee AH, Ryder K, Rytina ER, Fentiman IS - Br. J. Cancer (2002)

Overall survival is not related to the size of the largest axillary nodal metastasis in patients with occult metastasis or single node positive, χ2=0.52, P=0.91. Metastasis size was divided using cut-offs of 0.2, 2 and 10 mm.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2375207&req=5

fig2: Overall survival is not related to the size of the largest axillary nodal metastasis in patients with occult metastasis or single node positive, χ2=0.52, P=0.91. Metastasis size was divided using cut-offs of 0.2, 2 and 10 mm.
Mentions: Survival was not related to either the area or the largest diameter of the metastasis in the one-node positive and occult metastasis patients (Figure 2Figure 2

Bottom Line: The median follow-up was 18.9 years with 153 breast cancer related deaths.Multivariate analysis, however, showed that survival was related to tumour size and histological grade.We believe that the current evidence does not support the routine use of serial sections or immunohistochemistry for the detection of occult metastases in the management of lymph node negative patients, but that the traditional factors of histological grade and tumour size are useful.

View Article: PubMed Central - PubMed

Affiliation: Hedley Atkins ICRF Breast Pathology Laboratory, Guy's Hospital, London SE1 9RT, UK.

Show MeSH
Related in: MedlinePlus