Occult axillary lymph node metastases are of no prognostic significance in breast cancer.
Bottom Line: The median follow-up was 18.9 years with 153 breast cancer related deaths.Multivariate analysis, however, showed that survival was related to tumour size and histological grade.We believe that the current evidence does not support the routine use of serial sections or immunohistochemistry for the detection of occult metastases in the management of lymph node negative patients, but that the traditional factors of histological grade and tumour size are useful.
Affiliation: Hedley Atkins ICRF Breast Pathology Laboratory, Guy's Hospital, London SE1 9RT, UK.Show MeSH
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Affiliation: Hedley Atkins ICRF Breast Pathology Laboratory, Guy's Hospital, London SE1 9RT, UK.