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Clinical and economic impact of multiple gated acquisition scan monitoring during anthracycline therapy.

Shureiqi I, Cantor SB, Lippman SM, Brenner DE, Chernew ME, Fendrick AM - Br. J. Cancer (2002)

Bottom Line: The clinical and economic impacts of monitoring cardiac function in patients given doxorubicin have yet to be determined, especially in relation to patient age, cumulative doxorubicin dose, and the relative efficacies of doxorubicin-based vs alternative regimens.We developed a decision analysis model that includes these factors to estimate the incremental survival benefit and cost-effectiveness of using multiple gated acquisition scans to measure left-ventricular ejection fraction before and during doxorubicin chemotherapy.This incremental cost markedly decreased to $138 191, for patients between the ages of 40--59, and to $86 829 for patients older than 60 years.

View Article: PubMed Central - PubMed

Affiliation: The University of Texas M. D. Anderson Cancer Center, Department of Clinical Cancer Prevention, 1515 Holcombe Boulevard, Box 236, Houston, TX 77030, USA. ishureiqi@mdanderson.org

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Cost-effectiveness estimates for MUGA scan monitoring in patients given doxorubicin dose of ⩽350 mg m−2 ($/life saved).
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Related In: Results  -  Collection


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fig3: Cost-effectiveness estimates for MUGA scan monitoring in patients given doxorubicin dose of ⩽350 mg m−2 ($/life saved).

Mentions: Improvement in 5-year survival rates with MUGA screening in patients given doxorubicin for two cumulative dose thresholds (⩽350 and 500 mg m−2).


Clinical and economic impact of multiple gated acquisition scan monitoring during anthracycline therapy.

Shureiqi I, Cantor SB, Lippman SM, Brenner DE, Chernew ME, Fendrick AM - Br. J. Cancer (2002)

Cost-effectiveness estimates for MUGA scan monitoring in patients given doxorubicin dose of ⩽350 mg m−2 ($/life saved).
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2375190&req=5

fig3: Cost-effectiveness estimates for MUGA scan monitoring in patients given doxorubicin dose of ⩽350 mg m−2 ($/life saved).
Mentions: Improvement in 5-year survival rates with MUGA screening in patients given doxorubicin for two cumulative dose thresholds (⩽350 and 500 mg m−2).

Bottom Line: The clinical and economic impacts of monitoring cardiac function in patients given doxorubicin have yet to be determined, especially in relation to patient age, cumulative doxorubicin dose, and the relative efficacies of doxorubicin-based vs alternative regimens.We developed a decision analysis model that includes these factors to estimate the incremental survival benefit and cost-effectiveness of using multiple gated acquisition scans to measure left-ventricular ejection fraction before and during doxorubicin chemotherapy.This incremental cost markedly decreased to $138 191, for patients between the ages of 40--59, and to $86 829 for patients older than 60 years.

View Article: PubMed Central - PubMed

Affiliation: The University of Texas M. D. Anderson Cancer Center, Department of Clinical Cancer Prevention, 1515 Holcombe Boulevard, Box 236, Houston, TX 77030, USA. ishureiqi@mdanderson.org

Show MeSH
Related in: MedlinePlus