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Imaging findings in noncraniofacial childhood rhabdomyosarcoma.

Van Rijn RR, Wilde JC, Bras J, Oldenburger F, McHugh KM, Merks JH - Pediatr Radiol (2008)

Bottom Line: Rhabdomyosarcoma (RMS) is the most common soft-tissue sarcoma of childhood.This paper is focuses on imaging for diagnosis, staging, and follow-up of noncraniofacial RMS.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology, Academic Medical Centre Amsterdam, Suite G1-224, Meibergdreef 9, 1105 AZ, Amsterdam Zuid-Oost, The Netherlands. r.r.vanrijn@amc.uva.nl

ABSTRACT
Rhabdomyosarcoma (RMS) is the most common soft-tissue sarcoma of childhood. This paper is focuses on imaging for diagnosis, staging, and follow-up of noncraniofacial RMS.

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Related in: MedlinePlus

A 2-month-old boy with a mass in the third ray of the left foot. T1-W MR image shows a discrete lesion (open arrow) of intermediate signal intensity. Histopathology: embryonal RMS
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Fig13: A 2-month-old boy with a mass in the third ray of the left foot. T1-W MR image shows a discrete lesion (open arrow) of intermediate signal intensity. Histopathology: embryonal RMS

Mentions: RMS of the extremities (Figs. 12 and 13) is almost always of alveolar histology, tends to occur in older children and young adults, is often present with positive regional lymph nodes, and has a propensity to metastasize to unusual sites; these negative prognostic factors contribute to the relatively poor prognosis of RMS in this location [51, 52]. In approximately 12% of patients, nodal involvement is seen on imaging; however, when nodal dissection is performed the rate of nodal involvement increases to almost 50% [53]. This discrepancy between imaging findings and nodal dissection might be reduced by using high-quality state-of-the-art US. In current treatment protocols systematic biopsy of regional nodes is advocated, even if the nodes are not palpable or enlarged on imaging; sentinel node procedures are recommended whenever feasible, although the value of upgrading a patient to a higher risk group based merely on a positive sentinel node has not been studied yet. As in all tumours of the extremities, preoperative imaging plays a vital role in the depiction of the relationship between neurovascular bundles and the tumour.Fig. 12


Imaging findings in noncraniofacial childhood rhabdomyosarcoma.

Van Rijn RR, Wilde JC, Bras J, Oldenburger F, McHugh KM, Merks JH - Pediatr Radiol (2008)

A 2-month-old boy with a mass in the third ray of the left foot. T1-W MR image shows a discrete lesion (open arrow) of intermediate signal intensity. Histopathology: embryonal RMS
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2367394&req=5

Fig13: A 2-month-old boy with a mass in the third ray of the left foot. T1-W MR image shows a discrete lesion (open arrow) of intermediate signal intensity. Histopathology: embryonal RMS
Mentions: RMS of the extremities (Figs. 12 and 13) is almost always of alveolar histology, tends to occur in older children and young adults, is often present with positive regional lymph nodes, and has a propensity to metastasize to unusual sites; these negative prognostic factors contribute to the relatively poor prognosis of RMS in this location [51, 52]. In approximately 12% of patients, nodal involvement is seen on imaging; however, when nodal dissection is performed the rate of nodal involvement increases to almost 50% [53]. This discrepancy between imaging findings and nodal dissection might be reduced by using high-quality state-of-the-art US. In current treatment protocols systematic biopsy of regional nodes is advocated, even if the nodes are not palpable or enlarged on imaging; sentinel node procedures are recommended whenever feasible, although the value of upgrading a patient to a higher risk group based merely on a positive sentinel node has not been studied yet. As in all tumours of the extremities, preoperative imaging plays a vital role in the depiction of the relationship between neurovascular bundles and the tumour.Fig. 12

Bottom Line: Rhabdomyosarcoma (RMS) is the most common soft-tissue sarcoma of childhood.This paper is focuses on imaging for diagnosis, staging, and follow-up of noncraniofacial RMS.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology, Academic Medical Centre Amsterdam, Suite G1-224, Meibergdreef 9, 1105 AZ, Amsterdam Zuid-Oost, The Netherlands. r.r.vanrijn@amc.uva.nl

ABSTRACT
Rhabdomyosarcoma (RMS) is the most common soft-tissue sarcoma of childhood. This paper is focuses on imaging for diagnosis, staging, and follow-up of noncraniofacial RMS.

Show MeSH
Related in: MedlinePlus