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Synthesis, characterization, and biological activity of N-methyl-2-(1H-1,2,3-benzotriazol-1-y1)-3-oxobutan- ethioamide complexes with some divalent metal (II) ions.

Al-Awadi NA, Shuaib NM, Abbas A, El-Sherif AA, El-Dissouky A, Al-Saleh E - Bioinorg Chem Appl (2008)

Bottom Line: Thermal decomposition study of the complexes was monitored by TG and DTG analyses under N(2) atmosphere.The decomposition course and steps were analyzed and the activation parameters of the nonisothermal decomposition are determined.The isolated metal chelates have been screened for their antimicrobial activities and the findings have been reported and discussed in relation to their structures.

View Article: PubMed Central - PubMed

Affiliation: Chemistry Department, Faculty of Science, Kuwait University, P.O. Box 5969, Safat 13060, Kuwait.

ABSTRACT
A new series of Zn(2+), Cu(2+), Ni(2+), and Co(2+) complexes of N(1)-methyl-2-(1H-1,2,3-benzotriazol-1-yl)-3-oxobutanethioamide (MBOBT), HL, has been synthesized and characterized by different spectral and magnetic measurements and elemental analysis. IR spectral data indicates that (MBOBT) exists only in the thione form in the solid state while 13C NMR spectrum indicates its existence in thione and thiole tautomeric forms. The IR spectra of all complexes indicate that (MBOBT) acts as a monobasic bidentate ligand coordinating to the metal(II) ions via the keto-oxygen and thiolato-sulphur atoms. The electronic spectral studies showed that (MBOBT) bonded to all metal ions through sulphur and nitrogen atoms based on the positions and intensity of their charge transfer bands. Furthermore, the spectra reflect four coordinate tetrahedral zinc(II), tetragonally distorted copper(II), square planar nickel(II), and cobalt(II) complexes. Thermal decomposition study of the complexes was monitored by TG and DTG analyses under N(2) atmosphere. The decomposition course and steps were analyzed and the activation parameters of the nonisothermal decomposition are determined. The isolated metal chelates have been screened for their antimicrobial activities and the findings have been reported and discussed in relation to their structures.

No MeSH data available.


Related in: MedlinePlus

Effectof [L2Cu] on the respiration of Staphylococcus aurous.
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fig10: Effectof [L2Cu] on the respiration of Staphylococcus aurous.


Synthesis, characterization, and biological activity of N-methyl-2-(1H-1,2,3-benzotriazol-1-y1)-3-oxobutan- ethioamide complexes with some divalent metal (II) ions.

Al-Awadi NA, Shuaib NM, Abbas A, El-Sherif AA, El-Dissouky A, Al-Saleh E - Bioinorg Chem Appl (2008)

Effectof [L2Cu] on the respiration of Staphylococcus aurous.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2268950&req=5

fig10: Effectof [L2Cu] on the respiration of Staphylococcus aurous.
Bottom Line: Thermal decomposition study of the complexes was monitored by TG and DTG analyses under N(2) atmosphere.The decomposition course and steps were analyzed and the activation parameters of the nonisothermal decomposition are determined.The isolated metal chelates have been screened for their antimicrobial activities and the findings have been reported and discussed in relation to their structures.

View Article: PubMed Central - PubMed

Affiliation: Chemistry Department, Faculty of Science, Kuwait University, P.O. Box 5969, Safat 13060, Kuwait.

ABSTRACT
A new series of Zn(2+), Cu(2+), Ni(2+), and Co(2+) complexes of N(1)-methyl-2-(1H-1,2,3-benzotriazol-1-yl)-3-oxobutanethioamide (MBOBT), HL, has been synthesized and characterized by different spectral and magnetic measurements and elemental analysis. IR spectral data indicates that (MBOBT) exists only in the thione form in the solid state while 13C NMR spectrum indicates its existence in thione and thiole tautomeric forms. The IR spectra of all complexes indicate that (MBOBT) acts as a monobasic bidentate ligand coordinating to the metal(II) ions via the keto-oxygen and thiolato-sulphur atoms. The electronic spectral studies showed that (MBOBT) bonded to all metal ions through sulphur and nitrogen atoms based on the positions and intensity of their charge transfer bands. Furthermore, the spectra reflect four coordinate tetrahedral zinc(II), tetragonally distorted copper(II), square planar nickel(II), and cobalt(II) complexes. Thermal decomposition study of the complexes was monitored by TG and DTG analyses under N(2) atmosphere. The decomposition course and steps were analyzed and the activation parameters of the nonisothermal decomposition are determined. The isolated metal chelates have been screened for their antimicrobial activities and the findings have been reported and discussed in relation to their structures.

No MeSH data available.


Related in: MedlinePlus