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Synthesis, characterization, and biological activity of N-methyl-2-(1H-1,2,3-benzotriazol-1-y1)-3-oxobutan- ethioamide complexes with some divalent metal (II) ions.

Al-Awadi NA, Shuaib NM, Abbas A, El-Sherif AA, El-Dissouky A, Al-Saleh E - Bioinorg Chem Appl (2008)

Bottom Line: Thermal decomposition study of the complexes was monitored by TG and DTG analyses under N(2) atmosphere.The decomposition course and steps were analyzed and the activation parameters of the nonisothermal decomposition are determined.The isolated metal chelates have been screened for their antimicrobial activities and the findings have been reported and discussed in relation to their structures.

View Article: PubMed Central - PubMed

Affiliation: Chemistry Department, Faculty of Science, Kuwait University, P.O. Box 5969, Safat 13060, Kuwait.

ABSTRACT
A new series of Zn(2+), Cu(2+), Ni(2+), and Co(2+) complexes of N(1)-methyl-2-(1H-1,2,3-benzotriazol-1-yl)-3-oxobutanethioamide (MBOBT), HL, has been synthesized and characterized by different spectral and magnetic measurements and elemental analysis. IR spectral data indicates that (MBOBT) exists only in the thione form in the solid state while 13C NMR spectrum indicates its existence in thione and thiole tautomeric forms. The IR spectra of all complexes indicate that (MBOBT) acts as a monobasic bidentate ligand coordinating to the metal(II) ions via the keto-oxygen and thiolato-sulphur atoms. The electronic spectral studies showed that (MBOBT) bonded to all metal ions through sulphur and nitrogen atoms based on the positions and intensity of their charge transfer bands. Furthermore, the spectra reflect four coordinate tetrahedral zinc(II), tetragonally distorted copper(II), square planar nickel(II), and cobalt(II) complexes. Thermal decomposition study of the complexes was monitored by TG and DTG analyses under N(2) atmosphere. The decomposition course and steps were analyzed and the activation parameters of the nonisothermal decomposition are determined. The isolated metal chelates have been screened for their antimicrobial activities and the findings have been reported and discussed in relation to their structures.

No MeSH data available.


TG and DTG plots of[L2Cu].
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fig2: TG and DTG plots of[L2Cu].

Mentions: The thermogram given in Figure 2 of [L2Cu] exhibits two significantthermal events within the temperature range (158–549°C). The first step of decomposition within thetemperature range (158–316) corresponds to the loss of two BTA and two acetylene molecules with a mass loss 51.2% (calcd. 51.6%). The second step (449–549°C) corresponds to the loss of SO2 and L1 molecules (mass loss 30.9%; calcd. 31.2%). The energies ofactivation were 73.83 and 26.36 kJ mol−1 for the first and secondsteps, respectively. The total mass loss up to 549°C is in agreementwith the formation of CuS as the final residue (TG 17.2%, calcd. 17.9%).


Synthesis, characterization, and biological activity of N-methyl-2-(1H-1,2,3-benzotriazol-1-y1)-3-oxobutan- ethioamide complexes with some divalent metal (II) ions.

Al-Awadi NA, Shuaib NM, Abbas A, El-Sherif AA, El-Dissouky A, Al-Saleh E - Bioinorg Chem Appl (2008)

TG and DTG plots of[L2Cu].
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2268950&req=5

fig2: TG and DTG plots of[L2Cu].
Mentions: The thermogram given in Figure 2 of [L2Cu] exhibits two significantthermal events within the temperature range (158–549°C). The first step of decomposition within thetemperature range (158–316) corresponds to the loss of two BTA and two acetylene molecules with a mass loss 51.2% (calcd. 51.6%). The second step (449–549°C) corresponds to the loss of SO2 and L1 molecules (mass loss 30.9%; calcd. 31.2%). The energies ofactivation were 73.83 and 26.36 kJ mol−1 for the first and secondsteps, respectively. The total mass loss up to 549°C is in agreementwith the formation of CuS as the final residue (TG 17.2%, calcd. 17.9%).

Bottom Line: Thermal decomposition study of the complexes was monitored by TG and DTG analyses under N(2) atmosphere.The decomposition course and steps were analyzed and the activation parameters of the nonisothermal decomposition are determined.The isolated metal chelates have been screened for their antimicrobial activities and the findings have been reported and discussed in relation to their structures.

View Article: PubMed Central - PubMed

Affiliation: Chemistry Department, Faculty of Science, Kuwait University, P.O. Box 5969, Safat 13060, Kuwait.

ABSTRACT
A new series of Zn(2+), Cu(2+), Ni(2+), and Co(2+) complexes of N(1)-methyl-2-(1H-1,2,3-benzotriazol-1-yl)-3-oxobutanethioamide (MBOBT), HL, has been synthesized and characterized by different spectral and magnetic measurements and elemental analysis. IR spectral data indicates that (MBOBT) exists only in the thione form in the solid state while 13C NMR spectrum indicates its existence in thione and thiole tautomeric forms. The IR spectra of all complexes indicate that (MBOBT) acts as a monobasic bidentate ligand coordinating to the metal(II) ions via the keto-oxygen and thiolato-sulphur atoms. The electronic spectral studies showed that (MBOBT) bonded to all metal ions through sulphur and nitrogen atoms based on the positions and intensity of their charge transfer bands. Furthermore, the spectra reflect four coordinate tetrahedral zinc(II), tetragonally distorted copper(II), square planar nickel(II), and cobalt(II) complexes. Thermal decomposition study of the complexes was monitored by TG and DTG analyses under N(2) atmosphere. The decomposition course and steps were analyzed and the activation parameters of the nonisothermal decomposition are determined. The isolated metal chelates have been screened for their antimicrobial activities and the findings have been reported and discussed in relation to their structures.

No MeSH data available.