Limits...
Calcification of intervertebral discs in the dachshund: a radiographic and histopathologic study of 20 dogs.

Stigen Ø, Kolbjørnsen Ø - Acta Vet. Scand. (2007)

Bottom Line: A total of 148 (28.5%) calcified discs were identified at the radiographic and 230 (45.7%) at the histopathologic examination.All the intervertebral discs (n = 138) that were found to be calcified by radiography were also found to be calcified by histopathology.A sensitivity of 0.6 and specificity of 1.0 for radiography was calculated when using histopathology as the gold standard.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Companion Animal Clinical Sciences, Norwegian School of Veterinary Science, PO Box 8146, 0033 Oslo, Norway. oyvind.stigen@veths.no

ABSTRACT

Background: The purpose of the study was to compare radiographic and histopathologic findings with regard to number and extent of calcified discs in the dachshund.

Methods: The intervertebral discs of 20 dachshunds were subjected to a radiographic and histopathologic examination. The dogs were selected randomly from clinical cases euthanased for reasons unrelated to research at the Norwegian School of Veterinary Science. Lateral radiographs were taken of the vertebral columns after removing them from the carcasses. The histopathologic examination included 5 microm thick sections in the transverse plane, stained with hematoxylin-eosin and von Kossa. Radiographs and histological sections were evaluated independently.

Results: A total of 148 (28.5%) calcified discs were identified at the radiographic and 230 (45.7%) at the histopathologic examination. Of 92 discs found to be calcified by histopathology, but not by radiography, the degree of calcification was evaluated as 'slight' in 84 (91.3%). All the intervertebral discs (n = 138) that were found to be calcified by radiography were also found to be calcified by histopathology.

Conclusion: A sensitivity of 0.6 and specificity of 1.0 for radiography was calculated when using histopathology as the gold standard.

Show MeSH

Related in: MedlinePlus

Lateral radiograph from the seventh cervical (C7) to the fifth thoracic (T5) vertebra in a six-year-old, male, smoothcoated dachshund of standard size (Dog no. 10). Three intervertebral discs; T1–2, T3–4 and T4–5, shows a 'severe', 'moderate' or 'slight' degree of calcification (arrows).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC2262089&req=5

Figure 1: Lateral radiograph from the seventh cervical (C7) to the fifth thoracic (T5) vertebra in a six-year-old, male, smoothcoated dachshund of standard size (Dog no. 10). Three intervertebral discs; T1–2, T3–4 and T4–5, shows a 'severe', 'moderate' or 'slight' degree of calcification (arrows).

Mentions: At least four exposures were taken of each dog covering the vertebral column from the first cervical (C1) to the first sacral (S1) vertebra. The total number of calcified discs and their location in the vertebral column were recorded according to earlier described methods [13,14]. Three degrees of calcification of the individual discs were noted and defined as follows (Figure 1):


Calcification of intervertebral discs in the dachshund: a radiographic and histopathologic study of 20 dogs.

Stigen Ø, Kolbjørnsen Ø - Acta Vet. Scand. (2007)

Lateral radiograph from the seventh cervical (C7) to the fifth thoracic (T5) vertebra in a six-year-old, male, smoothcoated dachshund of standard size (Dog no. 10). Three intervertebral discs; T1–2, T3–4 and T4–5, shows a 'severe', 'moderate' or 'slight' degree of calcification (arrows).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2262089&req=5

Figure 1: Lateral radiograph from the seventh cervical (C7) to the fifth thoracic (T5) vertebra in a six-year-old, male, smoothcoated dachshund of standard size (Dog no. 10). Three intervertebral discs; T1–2, T3–4 and T4–5, shows a 'severe', 'moderate' or 'slight' degree of calcification (arrows).
Mentions: At least four exposures were taken of each dog covering the vertebral column from the first cervical (C1) to the first sacral (S1) vertebra. The total number of calcified discs and their location in the vertebral column were recorded according to earlier described methods [13,14]. Three degrees of calcification of the individual discs were noted and defined as follows (Figure 1):

Bottom Line: A total of 148 (28.5%) calcified discs were identified at the radiographic and 230 (45.7%) at the histopathologic examination.All the intervertebral discs (n = 138) that were found to be calcified by radiography were also found to be calcified by histopathology.A sensitivity of 0.6 and specificity of 1.0 for radiography was calculated when using histopathology as the gold standard.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Companion Animal Clinical Sciences, Norwegian School of Veterinary Science, PO Box 8146, 0033 Oslo, Norway. oyvind.stigen@veths.no

ABSTRACT

Background: The purpose of the study was to compare radiographic and histopathologic findings with regard to number and extent of calcified discs in the dachshund.

Methods: The intervertebral discs of 20 dachshunds were subjected to a radiographic and histopathologic examination. The dogs were selected randomly from clinical cases euthanased for reasons unrelated to research at the Norwegian School of Veterinary Science. Lateral radiographs were taken of the vertebral columns after removing them from the carcasses. The histopathologic examination included 5 microm thick sections in the transverse plane, stained with hematoxylin-eosin and von Kossa. Radiographs and histological sections were evaluated independently.

Results: A total of 148 (28.5%) calcified discs were identified at the radiographic and 230 (45.7%) at the histopathologic examination. Of 92 discs found to be calcified by histopathology, but not by radiography, the degree of calcification was evaluated as 'slight' in 84 (91.3%). All the intervertebral discs (n = 138) that were found to be calcified by radiography were also found to be calcified by histopathology.

Conclusion: A sensitivity of 0.6 and specificity of 1.0 for radiography was calculated when using histopathology as the gold standard.

Show MeSH
Related in: MedlinePlus