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Exploring of Antimicrobial Activity of Triphala Mashi-an Ayurvedic Formulation.

Biradar YS, Jagatap S, Khandelwal KR, Singhania SS - Evid Based Complement Alternat Med (2008)

Bottom Line: Triphala Mashi containing phenolic compounds, tannins exhibited comparable antimicrobial activity in relation to Triphala against all the microorganisms tested.It inhibits the dose-dependent growth of Gram-positive and Gram-negative bacteria.In conclusion, it appears that Triphala Mashi has non-specific antimicrobial activity.

View Article: PubMed Central - PubMed

Affiliation: Department of Pharmacognosy, Poona College of Pharmacy, Bharati Vidyapeeth Deemed University, Erandwane, Pune 411 038, Department of Microbiology, University of Pune and Department of Management Sciences, University of Pune, Pune, Maharashtra, India.

ABSTRACT
Triphala Mashi is an ayurvedic formulation that was prepared in our lab. Aqueous and alcoholic extracts of both Triphala and Triphala Mashi were used, to evaluate antimicrobial activity. Comparative phytochemical profile of Triphala and Triphala Mashi was done by preliminary phytochemical screening, total phenolic content and thin layer chromatography (TLC). Antimicrobial activity includes isolation of pathogens from clinical samples, its characterization, testing its multiple drug resistance against standard antibiotics and antimicrobial activity of aqueous and alcoholic extracts of both Triphala and Triphala Mashi against these organisms by using agar gel diffusion method. Triphala Mashi containing phenolic compounds, tannins exhibited comparable antimicrobial activity in relation to Triphala against all the microorganisms tested. It inhibits the dose-dependent growth of Gram-positive and Gram-negative bacteria. In conclusion, it appears that Triphala Mashi has non-specific antimicrobial activity.

No MeSH data available.


Antibacterial activity of Triphala and Triphala Mashi.
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Figure 1: Antibacterial activity of Triphala and Triphala Mashi.

Mentions: In general, the aqueous and ethanolic extracts of Triphala and Triphala Mashi exhibited a broad-spectrum antimicrobial activity against all the microorganisms from human secretions and from pathology lab with prior diagnosis. It inhibited the growth of all Gram-positive and Gram-negative bacteria. In agar diffusion method, with the broad range of concentrations of 50–1500 mg/ml of the extract, the growth of all microorganisms was inhibited. Aqueous extracts shows better activity than ethanolic extract for all strains. More inhibitory zone is observed for the strains E. coli, S. aureus. All extracts show dose-dependant activity (Fig. 1). All the microorganisms that presented resistance to certain tested antibiotics, showed good susceptibility to the extracts of Triphala and Triphala Mashi. Variations of susceptibilities and resistance existed among same microorganisms to the same antibiotics.Figure 1.


Exploring of Antimicrobial Activity of Triphala Mashi-an Ayurvedic Formulation.

Biradar YS, Jagatap S, Khandelwal KR, Singhania SS - Evid Based Complement Alternat Med (2008)

Antibacterial activity of Triphala and Triphala Mashi.
© Copyright Policy - creative-commons
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC2249739&req=5

Figure 1: Antibacterial activity of Triphala and Triphala Mashi.
Mentions: In general, the aqueous and ethanolic extracts of Triphala and Triphala Mashi exhibited a broad-spectrum antimicrobial activity against all the microorganisms from human secretions and from pathology lab with prior diagnosis. It inhibited the growth of all Gram-positive and Gram-negative bacteria. In agar diffusion method, with the broad range of concentrations of 50–1500 mg/ml of the extract, the growth of all microorganisms was inhibited. Aqueous extracts shows better activity than ethanolic extract for all strains. More inhibitory zone is observed for the strains E. coli, S. aureus. All extracts show dose-dependant activity (Fig. 1). All the microorganisms that presented resistance to certain tested antibiotics, showed good susceptibility to the extracts of Triphala and Triphala Mashi. Variations of susceptibilities and resistance existed among same microorganisms to the same antibiotics.Figure 1.

Bottom Line: Triphala Mashi containing phenolic compounds, tannins exhibited comparable antimicrobial activity in relation to Triphala against all the microorganisms tested.It inhibits the dose-dependent growth of Gram-positive and Gram-negative bacteria.In conclusion, it appears that Triphala Mashi has non-specific antimicrobial activity.

View Article: PubMed Central - PubMed

Affiliation: Department of Pharmacognosy, Poona College of Pharmacy, Bharati Vidyapeeth Deemed University, Erandwane, Pune 411 038, Department of Microbiology, University of Pune and Department of Management Sciences, University of Pune, Pune, Maharashtra, India.

ABSTRACT
Triphala Mashi is an ayurvedic formulation that was prepared in our lab. Aqueous and alcoholic extracts of both Triphala and Triphala Mashi were used, to evaluate antimicrobial activity. Comparative phytochemical profile of Triphala and Triphala Mashi was done by preliminary phytochemical screening, total phenolic content and thin layer chromatography (TLC). Antimicrobial activity includes isolation of pathogens from clinical samples, its characterization, testing its multiple drug resistance against standard antibiotics and antimicrobial activity of aqueous and alcoholic extracts of both Triphala and Triphala Mashi against these organisms by using agar gel diffusion method. Triphala Mashi containing phenolic compounds, tannins exhibited comparable antimicrobial activity in relation to Triphala against all the microorganisms tested. It inhibits the dose-dependent growth of Gram-positive and Gram-negative bacteria. In conclusion, it appears that Triphala Mashi has non-specific antimicrobial activity.

No MeSH data available.