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IDBD: infectious disease biomarker database.

Yang IS, Ryu C, Cho KJ, Kim JK, Ong SH, Mitchell WP, Kim BS, Oh HB, Kim KH - Nucleic Acids Res. (2007)

Bottom Line: Despite intensified interest and research, however, the overall rate of development of novel biomarkers has been falling.IDBD is a community annotation database, utilizing collaborative Web 2.0 features, providing a convenient user interface to input and revise data online.It supports various types of data searches and application tools to analyze sequence and structure features of potential and validated biomarkers.

View Article: PubMed Central - PubMed

Affiliation: Department of Life Sciences & Biotechnology, School of Life Sciences & Biotechnology, Korea University, Seoul, Korea.

ABSTRACT
Biomarkers enable early diagnosis, guide molecularly targeted therapy and monitor the activity and therapeutic responses across a variety of diseases. Despite intensified interest and research, however, the overall rate of development of novel biomarkers has been falling. Moreover, no solution is yet available that efficiently retrieves and processes biomarker information pertaining to infectious diseases. Infectious Disease Biomarker Database (IDBD) is one of the first efforts to build an easily accessible and comprehensive literature-derived database covering known infectious disease biomarkers. IDBD is a community annotation database, utilizing collaborative Web 2.0 features, providing a convenient user interface to input and revise data online. It allows users to link infectious diseases or pathogens to protein, gene or carbohydrate biomarkers through the use of search tools. It supports various types of data searches and application tools to analyze sequence and structure features of potential and validated biomarkers. Currently, IDBD integrates 611 biomarkers for 66 infectious diseases and 70 pathogens. It is publicly accessible at http://biomarker.cdc.go.kr and http://biomarker.korea.ac.kr.

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Related in: MedlinePlus

Search examples showing (A) three search options: Internal, External and News Search, (B) Internal Search results and (C) External Search results.
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Figure 2: Search examples showing (A) three search options: Internal, External and News Search, (B) Internal Search results and (C) External Search results.

Mentions: The complete contents of IDBD as well as other Web resources can be searched via its user-friendly interface. Three different search options are provided: Internal, External and News Search (Figure 2A). Internal Search can query via either title or content search which extracts textual content stored in the IDBD database including disease, pathogens and biomarkers (Figure 2B). In the case of External Search, users can submit a single query to the NCBI PubMed, NCBI Entrez sequence database, PDB structure database and Centers for Disease Control and Prevention (CDC) (Figure 2C). Details of published articles, sequence and structural data or disease and pathogen information can be viewed in abstract terms and sorted with regard to the information items. More detailed information can be retrieved by clicking the posting title of sorted search data. News Search provides accurate and timely information on the outbreaks and sporadic cases of any infectious diseases. Users can search current news or archives by entering keywords from scientific resources including BBC News, ScienceNow from Science magazine and Yahoo! News. More detailed information can be displayed by clicking on the title of news articles sorted by date.Figure 2.


IDBD: infectious disease biomarker database.

Yang IS, Ryu C, Cho KJ, Kim JK, Ong SH, Mitchell WP, Kim BS, Oh HB, Kim KH - Nucleic Acids Res. (2007)

Search examples showing (A) three search options: Internal, External and News Search, (B) Internal Search results and (C) External Search results.
© Copyright Policy - creative-commons
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2238845&req=5

Figure 2: Search examples showing (A) three search options: Internal, External and News Search, (B) Internal Search results and (C) External Search results.
Mentions: The complete contents of IDBD as well as other Web resources can be searched via its user-friendly interface. Three different search options are provided: Internal, External and News Search (Figure 2A). Internal Search can query via either title or content search which extracts textual content stored in the IDBD database including disease, pathogens and biomarkers (Figure 2B). In the case of External Search, users can submit a single query to the NCBI PubMed, NCBI Entrez sequence database, PDB structure database and Centers for Disease Control and Prevention (CDC) (Figure 2C). Details of published articles, sequence and structural data or disease and pathogen information can be viewed in abstract terms and sorted with regard to the information items. More detailed information can be retrieved by clicking the posting title of sorted search data. News Search provides accurate and timely information on the outbreaks and sporadic cases of any infectious diseases. Users can search current news or archives by entering keywords from scientific resources including BBC News, ScienceNow from Science magazine and Yahoo! News. More detailed information can be displayed by clicking on the title of news articles sorted by date.Figure 2.

Bottom Line: Despite intensified interest and research, however, the overall rate of development of novel biomarkers has been falling.IDBD is a community annotation database, utilizing collaborative Web 2.0 features, providing a convenient user interface to input and revise data online.It supports various types of data searches and application tools to analyze sequence and structure features of potential and validated biomarkers.

View Article: PubMed Central - PubMed

Affiliation: Department of Life Sciences & Biotechnology, School of Life Sciences & Biotechnology, Korea University, Seoul, Korea.

ABSTRACT
Biomarkers enable early diagnosis, guide molecularly targeted therapy and monitor the activity and therapeutic responses across a variety of diseases. Despite intensified interest and research, however, the overall rate of development of novel biomarkers has been falling. Moreover, no solution is yet available that efficiently retrieves and processes biomarker information pertaining to infectious diseases. Infectious Disease Biomarker Database (IDBD) is one of the first efforts to build an easily accessible and comprehensive literature-derived database covering known infectious disease biomarkers. IDBD is a community annotation database, utilizing collaborative Web 2.0 features, providing a convenient user interface to input and revise data online. It allows users to link infectious diseases or pathogens to protein, gene or carbohydrate biomarkers through the use of search tools. It supports various types of data searches and application tools to analyze sequence and structure features of potential and validated biomarkers. Currently, IDBD integrates 611 biomarkers for 66 infectious diseases and 70 pathogens. It is publicly accessible at http://biomarker.cdc.go.kr and http://biomarker.korea.ac.kr.

Show MeSH
Related in: MedlinePlus