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Inapparent twin malignancy in thyroglossal cyst: Case Report.

Vijay R, Rajan KK, Feroze M - World J Surg Oncol (2003)

Bottom Line: BACKGROUND: Although malignancy has been reported in thyroglossal cysts, synchronous occurrence of two malignancies is extremely rare.In view of the extreme rarity of the condition, controversies do exist regarding the optimal strategy to be adopted.The ideal procedure needs to be individually tailored and involve a combination of surgery, radio ablation, thyroid suppression and external radiotherapy.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of General Surgery, Calicut Medical College, Kozhikkode, Kerala, India. drvijayr1@yahoo.com

ABSTRACT
BACKGROUND: Although malignancy has been reported in thyroglossal cysts, synchronous occurrence of two malignancies is extremely rare. CASE REPORT: A case of concurrent papillary and squamous carcinoma arising in the thyroglossal cyst is presented here. CONCLUSIONS: Papillary and squamous carcinoma simultaneously occurring in a thyroglossal cyst is rarely diagnosed prior to surgery and pose a therapeutic dilemma. In view of the extreme rarity of the condition, controversies do exist regarding the optimal strategy to be adopted. The ideal procedure needs to be individually tailored and involve a combination of surgery, radio ablation, thyroid suppression and external radiotherapy.

No MeSH data available.


Related in: MedlinePlus

photomicrograph showing sheets of tumor cells with eosinophilic cytoplasm and hyperchromatic nucleus. Keratin pearl formation is seen. [Hematoxylin and Eosin ×200]
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Figure 2: photomicrograph showing sheets of tumor cells with eosinophilic cytoplasm and hyperchromatic nucleus. Keratin pearl formation is seen. [Hematoxylin and Eosin ×200]

Mentions: Histopathology of the resected specimen showed distinct foci of papillary carcinoma ([Figure 1) and squamous carcinoma (Figure 2) in the lateral cystic swelling and a normal thyroid gland. The midline swelling was found to have inflammatory tissue only. The patient was put on suppressive dose of thyroxin. Thyroid scintigraphy, radioiodine ablation of remnant thyroid and external beam radiotherapy to the tumor bed was planned however; the patient was lost to follow-up.


Inapparent twin malignancy in thyroglossal cyst: Case Report.

Vijay R, Rajan KK, Feroze M - World J Surg Oncol (2003)

photomicrograph showing sheets of tumor cells with eosinophilic cytoplasm and hyperchromatic nucleus. Keratin pearl formation is seen. [Hematoxylin and Eosin ×200]
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC222924&req=5

Figure 2: photomicrograph showing sheets of tumor cells with eosinophilic cytoplasm and hyperchromatic nucleus. Keratin pearl formation is seen. [Hematoxylin and Eosin ×200]
Mentions: Histopathology of the resected specimen showed distinct foci of papillary carcinoma ([Figure 1) and squamous carcinoma (Figure 2) in the lateral cystic swelling and a normal thyroid gland. The midline swelling was found to have inflammatory tissue only. The patient was put on suppressive dose of thyroxin. Thyroid scintigraphy, radioiodine ablation of remnant thyroid and external beam radiotherapy to the tumor bed was planned however; the patient was lost to follow-up.

Bottom Line: BACKGROUND: Although malignancy has been reported in thyroglossal cysts, synchronous occurrence of two malignancies is extremely rare.In view of the extreme rarity of the condition, controversies do exist regarding the optimal strategy to be adopted.The ideal procedure needs to be individually tailored and involve a combination of surgery, radio ablation, thyroid suppression and external radiotherapy.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of General Surgery, Calicut Medical College, Kozhikkode, Kerala, India. drvijayr1@yahoo.com

ABSTRACT
BACKGROUND: Although malignancy has been reported in thyroglossal cysts, synchronous occurrence of two malignancies is extremely rare. CASE REPORT: A case of concurrent papillary and squamous carcinoma arising in the thyroglossal cyst is presented here. CONCLUSIONS: Papillary and squamous carcinoma simultaneously occurring in a thyroglossal cyst is rarely diagnosed prior to surgery and pose a therapeutic dilemma. In view of the extreme rarity of the condition, controversies do exist regarding the optimal strategy to be adopted. The ideal procedure needs to be individually tailored and involve a combination of surgery, radio ablation, thyroid suppression and external radiotherapy.

No MeSH data available.


Related in: MedlinePlus