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Malignant fibrous histiocytoma of the face: report of a case.

Seper L, Schwab R, Kiattavorncharoen S, Büchter A, Bánkfalvi A, Joos U, Piffkó J, Kruse-Loesler B - Head Face Med (2007)

Bottom Line: Radical tumour resection was completed by extended parotidectomy and neck dissection; the skin defect was covered by a regional bi-lobed flap.Full functional and cosmetic recovery was achieved; follow-up has been uneventful more than two years postoperatively.Malignant transformation of BFH is extremely rare and if so, extended radical surgery may give a fair chance for a favourable outcome even in patients with advanced age.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Cranio-Maxillofacial Surgery, University of Muenster, Waldeyerstr, 30, 48149 Muenster, Germany. seper@uni-muenster.de

ABSTRACT

Background: Soft tissue sarcomas in the head and neck region are rare and often present a difficult differential diagnosis. The aim of our presentation is to point out the complexity of the diagnosis, treatment and follow up.

Case presentation: An eighty-seven year old female patient was referred to our unit with a fast growing brownish lump on the face. Four months beforehand, a benign fibrous histiocytoma (BFH) had been removed from the same location by excision biopsy with wide tumour-free resection margins. Excision biopsy of the recurrent lesion revealed a malignant fibrous histiocytoma (MFH). Radical tumour resection was completed by extended parotidectomy and neck dissection; the skin defect was covered by a regional bi-lobed flap. No adjuvant radio- or chemotherapy was administered. Full functional and cosmetic recovery was achieved; follow-up has been uneventful more than two years postoperatively.

Discussion: Malignant transformation of BFH is extremely rare and if so, extended radical surgery may give a fair chance for a favourable outcome even in patients with advanced age.

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Preoperative view of the lesion on the right cheek: a smooth, firm nodule with wide erythematous border.
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Figure 1: Preoperative view of the lesion on the right cheek: a smooth, firm nodule with wide erythematous border.

Mentions: An eighty-seven year old woman was referred to our department because of a fast-growing, dark-brownish, indurated skin nodule sized 3 cm in diameter, which infiltrated the skin and the deeper soft tissue layers of the face (Fig 1.) Four months beforehand, a benign cutaneous histiocytoma (BFH) had been removed from the same location by excision biopsy (Fig. 2a–d), which had been a painless, slow-growing, brownish lump not exceeding 1 cm in diameter clinically. Surgical margins had been disease-free.


Malignant fibrous histiocytoma of the face: report of a case.

Seper L, Schwab R, Kiattavorncharoen S, Büchter A, Bánkfalvi A, Joos U, Piffkó J, Kruse-Loesler B - Head Face Med (2007)

Preoperative view of the lesion on the right cheek: a smooth, firm nodule with wide erythematous border.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2211745&req=5

Figure 1: Preoperative view of the lesion on the right cheek: a smooth, firm nodule with wide erythematous border.
Mentions: An eighty-seven year old woman was referred to our department because of a fast-growing, dark-brownish, indurated skin nodule sized 3 cm in diameter, which infiltrated the skin and the deeper soft tissue layers of the face (Fig 1.) Four months beforehand, a benign cutaneous histiocytoma (BFH) had been removed from the same location by excision biopsy (Fig. 2a–d), which had been a painless, slow-growing, brownish lump not exceeding 1 cm in diameter clinically. Surgical margins had been disease-free.

Bottom Line: Radical tumour resection was completed by extended parotidectomy and neck dissection; the skin defect was covered by a regional bi-lobed flap.Full functional and cosmetic recovery was achieved; follow-up has been uneventful more than two years postoperatively.Malignant transformation of BFH is extremely rare and if so, extended radical surgery may give a fair chance for a favourable outcome even in patients with advanced age.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Cranio-Maxillofacial Surgery, University of Muenster, Waldeyerstr, 30, 48149 Muenster, Germany. seper@uni-muenster.de

ABSTRACT

Background: Soft tissue sarcomas in the head and neck region are rare and often present a difficult differential diagnosis. The aim of our presentation is to point out the complexity of the diagnosis, treatment and follow up.

Case presentation: An eighty-seven year old female patient was referred to our unit with a fast growing brownish lump on the face. Four months beforehand, a benign fibrous histiocytoma (BFH) had been removed from the same location by excision biopsy with wide tumour-free resection margins. Excision biopsy of the recurrent lesion revealed a malignant fibrous histiocytoma (MFH). Radical tumour resection was completed by extended parotidectomy and neck dissection; the skin defect was covered by a regional bi-lobed flap. No adjuvant radio- or chemotherapy was administered. Full functional and cosmetic recovery was achieved; follow-up has been uneventful more than two years postoperatively.

Discussion: Malignant transformation of BFH is extremely rare and if so, extended radical surgery may give a fair chance for a favourable outcome even in patients with advanced age.

Show MeSH
Related in: MedlinePlus