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Direct visualization of a significant stenosis of the right coronary artery by transthoracic echocardiography. A case report.

Holte E, Vegsundvåg J, Wiseth R - Cardiovasc Ultrasound (2007)

Bottom Line: Coronary artery stenoses can be identified as localized colour aliasing and accelerated flow velocities.The CVFR of RCA measured in the RDP showed normal vasodilatory response, confirming an open RCA without any flow limitation.A repeated coronary angiogram demonstrated only a mild in stent intimal hyperplasia.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Internal Medicine, Alesund Hospital, Alesund, Norway. es-holte@online.no

ABSTRACT
Non-invasive imaging of coronary arteries by transthoracic echocardiography is an emerging diagnostic tool to study the left main (LM), left descending artery (LAD), circumflex (Cx) and right coronary artery (RCA). Impaired coronary circulation can be assessed by measuring coronary velocity flow reserve (CVFR) by transthoracic Doppler echocardiography. Coronary artery stenoses can be identified as localized colour aliasing and accelerated flow velocities. We report a case with an acute coronary syndrome (ACS) of a 46-year-old man. With non-invasive imaging of coronary arteries by transthoracic echocardiography (TTE), we identified a segment of the mid right coronary artery (RCA) suggestive of stenosis with localized colour aliasing and accelerated flow velocity. We found a high ratio between the stenotic peak velocity and the prestenotic peak velocity, and a pathologic coronary flow velocity reserve (CFVR) distal to the stenosis in the posterior interventricular descending branch (RDP). Subsequent coronary angiography demonstrated one vessel disease with a stenosis in segment 3 of RCA, which was successfully treated with percutaneos coronary intervention PCI. Two weeks following the PCI procedure he was readmitted to hospital with chest pain. A subacute stent thrombosis was questioned, and repeated echocardiography was preformed. The mid portion of RCA showed normal and laminar flow. The CVFR of RCA measured in the RDP showed normal vasodilatory response, confirming an open RCA without any flow limitation. A repeated coronary angiogram demonstrated only a mild in stent intimal hyperplasia. This case illustrates the value of transthoracic echocardiography as a tool both in the diagnosis and the follow-up of chest pain disorders and coronary flow problems. Transthoracic echocardiography allows both direct visualization of the various coronary segments and assessment of the CVFR.

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CVFR of RDP. Peak diastolic velocity of RDP baseline 0.41 m/s. Peak diastolic velocity of RDP adenosine (enveloped) 0.48 m/s.
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Figure 2: CVFR of RDP. Peak diastolic velocity of RDP baseline 0.41 m/s. Peak diastolic velocity of RDP adenosine (enveloped) 0.48 m/s.

Mentions: From a modified apical 2-chamber view the CVFR was measured both in the RDP and the distal segment of LAD, and hyperaemic flow was obtained by venous infusion of adenosine (140 μcg/kg/min). The CVFR of the LAD was normal (Table 1), indicating that the LAD was open with good microvascular function and without any significant stenosis. The CVFR value of 1.17 measured in the RDP was clearly pathologic (Table 1, Figure 2), indicating an obstructive lesion proximal to the RDP, most likely in the mid segment of the RCA.


Direct visualization of a significant stenosis of the right coronary artery by transthoracic echocardiography. A case report.

Holte E, Vegsundvåg J, Wiseth R - Cardiovasc Ultrasound (2007)

CVFR of RDP. Peak diastolic velocity of RDP baseline 0.41 m/s. Peak diastolic velocity of RDP adenosine (enveloped) 0.48 m/s.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2100043&req=5

Figure 2: CVFR of RDP. Peak diastolic velocity of RDP baseline 0.41 m/s. Peak diastolic velocity of RDP adenosine (enveloped) 0.48 m/s.
Mentions: From a modified apical 2-chamber view the CVFR was measured both in the RDP and the distal segment of LAD, and hyperaemic flow was obtained by venous infusion of adenosine (140 μcg/kg/min). The CVFR of the LAD was normal (Table 1), indicating that the LAD was open with good microvascular function and without any significant stenosis. The CVFR value of 1.17 measured in the RDP was clearly pathologic (Table 1, Figure 2), indicating an obstructive lesion proximal to the RDP, most likely in the mid segment of the RCA.

Bottom Line: Coronary artery stenoses can be identified as localized colour aliasing and accelerated flow velocities.The CVFR of RCA measured in the RDP showed normal vasodilatory response, confirming an open RCA without any flow limitation.A repeated coronary angiogram demonstrated only a mild in stent intimal hyperplasia.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Internal Medicine, Alesund Hospital, Alesund, Norway. es-holte@online.no

ABSTRACT
Non-invasive imaging of coronary arteries by transthoracic echocardiography is an emerging diagnostic tool to study the left main (LM), left descending artery (LAD), circumflex (Cx) and right coronary artery (RCA). Impaired coronary circulation can be assessed by measuring coronary velocity flow reserve (CVFR) by transthoracic Doppler echocardiography. Coronary artery stenoses can be identified as localized colour aliasing and accelerated flow velocities. We report a case with an acute coronary syndrome (ACS) of a 46-year-old man. With non-invasive imaging of coronary arteries by transthoracic echocardiography (TTE), we identified a segment of the mid right coronary artery (RCA) suggestive of stenosis with localized colour aliasing and accelerated flow velocity. We found a high ratio between the stenotic peak velocity and the prestenotic peak velocity, and a pathologic coronary flow velocity reserve (CFVR) distal to the stenosis in the posterior interventricular descending branch (RDP). Subsequent coronary angiography demonstrated one vessel disease with a stenosis in segment 3 of RCA, which was successfully treated with percutaneos coronary intervention PCI. Two weeks following the PCI procedure he was readmitted to hospital with chest pain. A subacute stent thrombosis was questioned, and repeated echocardiography was preformed. The mid portion of RCA showed normal and laminar flow. The CVFR of RCA measured in the RDP showed normal vasodilatory response, confirming an open RCA without any flow limitation. A repeated coronary angiogram demonstrated only a mild in stent intimal hyperplasia. This case illustrates the value of transthoracic echocardiography as a tool both in the diagnosis and the follow-up of chest pain disorders and coronary flow problems. Transthoracic echocardiography allows both direct visualization of the various coronary segments and assessment of the CVFR.

Show MeSH
Related in: MedlinePlus