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Mucin-associated sialosyl-Tn antigen expression in gastric cancer correlates with an adverse outcome.

Werther JL, Rivera-MacMurray S, Bruckner H, Tatematsu M, Itzkowitz SH - Br. J. Cancer (1994)

Bottom Line: Twenty-one of 31 (68%) gastric cancers expressed STn, regardless of tumour location, stage or histological type.Eighty-one per cent of patients with STn-positive tumours died of their disease or had recurrent cancer, compared with 20% of patients with STn-negative tumours (P < 0.002).STn may be a useful prognostic marker in patients with gastric cancer.

View Article: PubMed Central - PubMed

Affiliation: Department of Medicine, Mount Sinai School of Medicine, New York, NY 10029.

ABSTRACT
The expression of sialosyl-Tn (STn) antigen was evaluated by immunohistochemistry in primary gastric cancers. Twenty-one of 31 (68%) gastric cancers expressed STn, regardless of tumour location, stage or histological type. Eighty-one per cent of patients with STn-positive tumours died of their disease or had recurrent cancer, compared with 20% of patients with STn-negative tumours (P < 0.002). STn may be a useful prognostic marker in patients with gastric cancer.

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Related in: MedlinePlus

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Mucin-associated sialosyl-Tn antigen expression in gastric cancer correlates with an adverse outcome.

Werther JL, Rivera-MacMurray S, Bruckner H, Tatematsu M, Itzkowitz SH - Br. J. Cancer (1994)

© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC1968851&req=5

Bottom Line: Twenty-one of 31 (68%) gastric cancers expressed STn, regardless of tumour location, stage or histological type.Eighty-one per cent of patients with STn-positive tumours died of their disease or had recurrent cancer, compared with 20% of patients with STn-negative tumours (P < 0.002).STn may be a useful prognostic marker in patients with gastric cancer.

View Article: PubMed Central - PubMed

Affiliation: Department of Medicine, Mount Sinai School of Medicine, New York, NY 10029.

ABSTRACT
The expression of sialosyl-Tn (STn) antigen was evaluated by immunohistochemistry in primary gastric cancers. Twenty-one of 31 (68%) gastric cancers expressed STn, regardless of tumour location, stage or histological type. Eighty-one per cent of patients with STn-positive tumours died of their disease or had recurrent cancer, compared with 20% of patients with STn-negative tumours (P < 0.002). STn may be a useful prognostic marker in patients with gastric cancer.

Show MeSH
Related in: MedlinePlus