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Prior exercise does not affect chylomicron particle number following a mixed meal of moderate fat content.

James AP, Slivkoff-Clark K, Mamo JC - Lipids Health Dis (2007)

Bottom Line: In a randomised crossover design eight lean and healthy male and female subjects attended two postprandial testing days.Fasting blood samples were then collected prior to ingestion of a moderate fat mixed meal (0.44 g fat, 0.94 g carbohydrate, 0.27 g protein/kg body weight), blood was then collected after 1 h, 2 h, 4 h, 6 h, and 8 h.A single session of exercise of moderate intensity and 90 minutes duration reduces fasting triacylglycerol levels, however fasting and postprandial chylomicron particle number was unaffected.

View Article: PubMed Central - HTML - PubMed

Affiliation: School of Public Health, Australian Technology Centre for Metabolic Fitness, Curtin University of Technology, Perth, WA, Australia. T.P.James@curtin.edu.au

ABSTRACT

Background: A single session of exercise has been reported to reduce fasting and postprandial triacylglycerol concentrations on the subsequent day. It is possible that exercise also reduces chylomicron particle number, which may underlie the observed reduction in postprandial triacylglycerol concentration. In the present study we aimed to determine whether a single session of exercise reduces fasting and postprandial chylomicron particle number on the subsequent day. In a randomised crossover design eight lean and healthy male and female subjects attended two postprandial testing days. On the previous day the subjects either performed 90 minutes of moderate intensity exercise or did not perform any exercise. Fasting blood samples were then collected prior to ingestion of a moderate fat mixed meal (0.44 g fat, 0.94 g carbohydrate, 0.27 g protein/kg body weight), blood was then collected after 1 h, 2 h, 4 h, 6 h, and 8 h.

Results: The fasting and postprandial apolipoprotein B48 concentration (marker of chylomicron particle number) was not affected by prior exercise. However exercise reduced fasting triacylglycerol concentration by 16% (P < 0.05) and there was a trend towards a reduction in the total area under the postprandial triacylglycerol curve (23%; P = 0.053). However when corrected for baseline concentration postprandial triacylglycerol concentration was not affected by prior exercise.

Conclusion: A single session of exercise of moderate intensity and 90 minutes duration reduces fasting triacylglycerol levels, however fasting and postprandial chylomicron particle number was unaffected. Furthermore it appears that previously observed reductions in postprandial triacylglycerol levels following exercise are only mediated following consumption of high, non-physiologically relevant doses of fat.

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Serum concentrations of triacylglycerol and apolipoprotein B48 in the fasting and postprandial states. Shown are the concentrations, mean and standard error of triacylglycerol (A) and apolipoprotein B48 (B) in the fasting state (0 h) and for 8 h after consumption of the moderate fat mixed meal in control (closed squares; blue) and prior exercise (open squares; red) trials. Summary measures are shown in Table 3.
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Figure 1: Serum concentrations of triacylglycerol and apolipoprotein B48 in the fasting and postprandial states. Shown are the concentrations, mean and standard error of triacylglycerol (A) and apolipoprotein B48 (B) in the fasting state (0 h) and for 8 h after consumption of the moderate fat mixed meal in control (closed squares; blue) and prior exercise (open squares; red) trials. Summary measures are shown in Table 3.

Mentions: The fasting serum apo B48 concentration was not affected by prior exercise (Figure 1, Table 3). Following consumption of the test meal no change in either the total or incremental areas under the postprandial apo B48 curves was observed (Figure 1, Table 3).


Prior exercise does not affect chylomicron particle number following a mixed meal of moderate fat content.

James AP, Slivkoff-Clark K, Mamo JC - Lipids Health Dis (2007)

Serum concentrations of triacylglycerol and apolipoprotein B48 in the fasting and postprandial states. Shown are the concentrations, mean and standard error of triacylglycerol (A) and apolipoprotein B48 (B) in the fasting state (0 h) and for 8 h after consumption of the moderate fat mixed meal in control (closed squares; blue) and prior exercise (open squares; red) trials. Summary measures are shown in Table 3.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC1851010&req=5

Figure 1: Serum concentrations of triacylglycerol and apolipoprotein B48 in the fasting and postprandial states. Shown are the concentrations, mean and standard error of triacylglycerol (A) and apolipoprotein B48 (B) in the fasting state (0 h) and for 8 h after consumption of the moderate fat mixed meal in control (closed squares; blue) and prior exercise (open squares; red) trials. Summary measures are shown in Table 3.
Mentions: The fasting serum apo B48 concentration was not affected by prior exercise (Figure 1, Table 3). Following consumption of the test meal no change in either the total or incremental areas under the postprandial apo B48 curves was observed (Figure 1, Table 3).

Bottom Line: In a randomised crossover design eight lean and healthy male and female subjects attended two postprandial testing days.Fasting blood samples were then collected prior to ingestion of a moderate fat mixed meal (0.44 g fat, 0.94 g carbohydrate, 0.27 g protein/kg body weight), blood was then collected after 1 h, 2 h, 4 h, 6 h, and 8 h.A single session of exercise of moderate intensity and 90 minutes duration reduces fasting triacylglycerol levels, however fasting and postprandial chylomicron particle number was unaffected.

View Article: PubMed Central - HTML - PubMed

Affiliation: School of Public Health, Australian Technology Centre for Metabolic Fitness, Curtin University of Technology, Perth, WA, Australia. T.P.James@curtin.edu.au

ABSTRACT

Background: A single session of exercise has been reported to reduce fasting and postprandial triacylglycerol concentrations on the subsequent day. It is possible that exercise also reduces chylomicron particle number, which may underlie the observed reduction in postprandial triacylglycerol concentration. In the present study we aimed to determine whether a single session of exercise reduces fasting and postprandial chylomicron particle number on the subsequent day. In a randomised crossover design eight lean and healthy male and female subjects attended two postprandial testing days. On the previous day the subjects either performed 90 minutes of moderate intensity exercise or did not perform any exercise. Fasting blood samples were then collected prior to ingestion of a moderate fat mixed meal (0.44 g fat, 0.94 g carbohydrate, 0.27 g protein/kg body weight), blood was then collected after 1 h, 2 h, 4 h, 6 h, and 8 h.

Results: The fasting and postprandial apolipoprotein B48 concentration (marker of chylomicron particle number) was not affected by prior exercise. However exercise reduced fasting triacylglycerol concentration by 16% (P < 0.05) and there was a trend towards a reduction in the total area under the postprandial triacylglycerol curve (23%; P = 0.053). However when corrected for baseline concentration postprandial triacylglycerol concentration was not affected by prior exercise.

Conclusion: A single session of exercise of moderate intensity and 90 minutes duration reduces fasting triacylglycerol levels, however fasting and postprandial chylomicron particle number was unaffected. Furthermore it appears that previously observed reductions in postprandial triacylglycerol levels following exercise are only mediated following consumption of high, non-physiologically relevant doses of fat.

Show MeSH