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A case-control study of osteopathic palpatory findings in type 2 diabetes mellitus.

Licciardone JC, Fulda KG, Stoll ST, Gamber RG, Cage AC - Osteopath Med Prim Care (2007)

Bottom Line: OR, 32.00; 95% CI, 2.29-448; P = .01 for long duration on the left side; and OR, 17.33; 95% CI, 1.39-217; P = .03 for short duration vs.OR, 32.00; 95% CI, 2.29-448; P = .01 for long duration on the right side).Potential explanations for this finding include reflex viscerosomatic changes directly related to the progression of type 2 diabetes mellitus, a spurious association attributable to confounding visceral diseases, or a chance observation unrelated to type 2 diabetes mellitus.

View Article: PubMed Central - HTML - PubMed

Affiliation: Osteopathic Research Center, University of North Texas Health Science Center-Texas College of Osteopathic Medicine, Fort Worth, TX 76107, USA. licciar@hsc.unt.edu

ABSTRACT

Background: Although type 2 diabetes mellitus is often managed by osteopathic physicians, osteopathic palpatory findings in this disease have not been adequately studied.

Methods: A case-control study was used to measure the association between type 2 diabetes mellitus and a series of 30 osteopathic palpatory findings. The latter included skin changes, trophic changes, tissue changes, tenderness, and immobility at spinal segmental levels T5-T7, T8-T10, and T11-L2 bilaterally. Logistic regression models that adjusted for age, sex, and comorbid conditions were used to compute odds ratios (ORs) and 95% confidence intervals (CIs) for the associations between type 2 diabetes mellitus and each of these findings.

Results and discussion: A total of 92 subjects were included in the study. After controlling for age, sex, hypertension, and clinical depression, the only significant finding was an association between type 2 diabetes mellitus and tissue changes at T11-L2 on the right side (OR, 5.54; 95% CI, 1.76-17.47; P = .003). Subgroup analyses of subjects with type 2 diabetes mellitus and hypertension demonstrated significant associations with tissue changes at T11-L2 bilaterally (OR, 27.38; 95% CI, 1.75-428; P = .02 for the left side and OR, 24.00; 95% CI, 1.51-382; P = .02 for the right side). Among subjects with type 2 diabetes mellitus and hypertension, there was also a strong diabetes mellitus duration effect for tissue changes at T11-L2 bilaterally (OR, 12.00; 95% CI, 1.02-141; P = .05 for short duration vs. OR, 32.00; 95% CI, 2.29-448; P = .01 for long duration on the left side; and OR, 17.33; 95% CI, 1.39-217; P = .03 for short duration vs. OR, 32.00; 95% CI, 2.29-448; P = .01 for long duration on the right side).

Conclusion: The only consistent finding in this study was an association between type 2 diabetes mellitus and tissue changes at T11-L2 on the right side. Potential explanations for this finding include reflex viscerosomatic changes directly related to the progression of type 2 diabetes mellitus, a spurious association attributable to confounding visceral diseases, or a chance observation unrelated to type 2 diabetes mellitus. Larger prospective studies are needed to better study osteopathic palpatory findings in type 2 diabetes mellitus.

No MeSH data available.


Related in: MedlinePlus

Columnar graphs of osteopathic palpatory findings according to element of somatic dysfunction, spinal segmental level, and laterality. The columns represent the proportion of subjects with a positive osteopathic palpatory finding.
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Figure 2: Columnar graphs of osteopathic palpatory findings according to element of somatic dysfunction, spinal segmental level, and laterality. The columns represent the proportion of subjects with a positive osteopathic palpatory finding.

Mentions: The number of subjects with and without positive osteopathic palpatory findings according to element of somatic dysfunction, spinal segmental level, and laterality is presented in Table 3. The prevalence of these osteopathic palpatory findings (i.e., the proportion of subjects with positive osteopathic palpatory findings) is depicted in Figure 2. Immobility and tissue changes were the most common osteopathic palpatory findings.


A case-control study of osteopathic palpatory findings in type 2 diabetes mellitus.

Licciardone JC, Fulda KG, Stoll ST, Gamber RG, Cage AC - Osteopath Med Prim Care (2007)

Columnar graphs of osteopathic palpatory findings according to element of somatic dysfunction, spinal segmental level, and laterality. The columns represent the proportion of subjects with a positive osteopathic palpatory finding.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC1808472&req=5

Figure 2: Columnar graphs of osteopathic palpatory findings according to element of somatic dysfunction, spinal segmental level, and laterality. The columns represent the proportion of subjects with a positive osteopathic palpatory finding.
Mentions: The number of subjects with and without positive osteopathic palpatory findings according to element of somatic dysfunction, spinal segmental level, and laterality is presented in Table 3. The prevalence of these osteopathic palpatory findings (i.e., the proportion of subjects with positive osteopathic palpatory findings) is depicted in Figure 2. Immobility and tissue changes were the most common osteopathic palpatory findings.

Bottom Line: OR, 32.00; 95% CI, 2.29-448; P = .01 for long duration on the left side; and OR, 17.33; 95% CI, 1.39-217; P = .03 for short duration vs.OR, 32.00; 95% CI, 2.29-448; P = .01 for long duration on the right side).Potential explanations for this finding include reflex viscerosomatic changes directly related to the progression of type 2 diabetes mellitus, a spurious association attributable to confounding visceral diseases, or a chance observation unrelated to type 2 diabetes mellitus.

View Article: PubMed Central - HTML - PubMed

Affiliation: Osteopathic Research Center, University of North Texas Health Science Center-Texas College of Osteopathic Medicine, Fort Worth, TX 76107, USA. licciar@hsc.unt.edu

ABSTRACT

Background: Although type 2 diabetes mellitus is often managed by osteopathic physicians, osteopathic palpatory findings in this disease have not been adequately studied.

Methods: A case-control study was used to measure the association between type 2 diabetes mellitus and a series of 30 osteopathic palpatory findings. The latter included skin changes, trophic changes, tissue changes, tenderness, and immobility at spinal segmental levels T5-T7, T8-T10, and T11-L2 bilaterally. Logistic regression models that adjusted for age, sex, and comorbid conditions were used to compute odds ratios (ORs) and 95% confidence intervals (CIs) for the associations between type 2 diabetes mellitus and each of these findings.

Results and discussion: A total of 92 subjects were included in the study. After controlling for age, sex, hypertension, and clinical depression, the only significant finding was an association between type 2 diabetes mellitus and tissue changes at T11-L2 on the right side (OR, 5.54; 95% CI, 1.76-17.47; P = .003). Subgroup analyses of subjects with type 2 diabetes mellitus and hypertension demonstrated significant associations with tissue changes at T11-L2 bilaterally (OR, 27.38; 95% CI, 1.75-428; P = .02 for the left side and OR, 24.00; 95% CI, 1.51-382; P = .02 for the right side). Among subjects with type 2 diabetes mellitus and hypertension, there was also a strong diabetes mellitus duration effect for tissue changes at T11-L2 bilaterally (OR, 12.00; 95% CI, 1.02-141; P = .05 for short duration vs. OR, 32.00; 95% CI, 2.29-448; P = .01 for long duration on the left side; and OR, 17.33; 95% CI, 1.39-217; P = .03 for short duration vs. OR, 32.00; 95% CI, 2.29-448; P = .01 for long duration on the right side).

Conclusion: The only consistent finding in this study was an association between type 2 diabetes mellitus and tissue changes at T11-L2 on the right side. Potential explanations for this finding include reflex viscerosomatic changes directly related to the progression of type 2 diabetes mellitus, a spurious association attributable to confounding visceral diseases, or a chance observation unrelated to type 2 diabetes mellitus. Larger prospective studies are needed to better study osteopathic palpatory findings in type 2 diabetes mellitus.

No MeSH data available.


Related in: MedlinePlus