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Solitary neurofibroma in the male breast.

Jeyaretna DS, Oriolowo A, Smith ME, Watkins RM - World J Surg Oncol (2007)

Bottom Line: Neurofibroma of the male breast outside of neurofibromatosis is extremely rare with only one previous case having been reported.A 48 year old male patient with a neurofibroma in the breast presenting with gynaecomastia is reported.To our knowledge this is only the second case of a neurofibroma in a male breast in the English literature and the first report to include the mammographic findings.

View Article: PubMed Central - HTML - PubMed

Affiliation: Primrose Breast Care Centre, Derriford Hospital, Plymouth, UK. sanjeeva@doctors.org.uk

ABSTRACT

Background: Neurofibroma of the male breast outside of neurofibromatosis is extremely rare with only one previous case having been reported.

Case presentation: A 48 year old male patient with a neurofibroma in the breast presenting with gynaecomastia is reported. Clinical and mammogram findings with fine needle aspiration cytology and full histology are presented.

Conclusion: To our knowledge this is only the second case of a neurofibroma in a male breast in the English literature and the first report to include the mammographic findings.

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Related in: MedlinePlus

Photomicrograph of the resected neurofibroma showing spindle cells with characteristic elongated, wavy nuclei. (20× magnification, Haematoxylin and Eosin)
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Figure 2: Photomicrograph of the resected neurofibroma showing spindle cells with characteristic elongated, wavy nuclei. (20× magnification, Haematoxylin and Eosin)

Mentions: Macroscopically the tumour measured 4 × 3 × 2.5 cm, was white and well circumscribed. Microscopically it was moderately cellular and it contained spindle cells with irregular and focally pleomorphic nuclei. No mitoses or necrosis were seen (Figure 2). No Antoni A areas were present. A definitive histological diagnosis of a benign cellular neurofibroma was made. After 5-years no recurrence has been observed.


Solitary neurofibroma in the male breast.

Jeyaretna DS, Oriolowo A, Smith ME, Watkins RM - World J Surg Oncol (2007)

Photomicrograph of the resected neurofibroma showing spindle cells with characteristic elongated, wavy nuclei. (20× magnification, Haematoxylin and Eosin)
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC1808458&req=5

Figure 2: Photomicrograph of the resected neurofibroma showing spindle cells with characteristic elongated, wavy nuclei. (20× magnification, Haematoxylin and Eosin)
Mentions: Macroscopically the tumour measured 4 × 3 × 2.5 cm, was white and well circumscribed. Microscopically it was moderately cellular and it contained spindle cells with irregular and focally pleomorphic nuclei. No mitoses or necrosis were seen (Figure 2). No Antoni A areas were present. A definitive histological diagnosis of a benign cellular neurofibroma was made. After 5-years no recurrence has been observed.

Bottom Line: Neurofibroma of the male breast outside of neurofibromatosis is extremely rare with only one previous case having been reported.A 48 year old male patient with a neurofibroma in the breast presenting with gynaecomastia is reported.To our knowledge this is only the second case of a neurofibroma in a male breast in the English literature and the first report to include the mammographic findings.

View Article: PubMed Central - HTML - PubMed

Affiliation: Primrose Breast Care Centre, Derriford Hospital, Plymouth, UK. sanjeeva@doctors.org.uk

ABSTRACT

Background: Neurofibroma of the male breast outside of neurofibromatosis is extremely rare with only one previous case having been reported.

Case presentation: A 48 year old male patient with a neurofibroma in the breast presenting with gynaecomastia is reported. Clinical and mammogram findings with fine needle aspiration cytology and full histology are presented.

Conclusion: To our knowledge this is only the second case of a neurofibroma in a male breast in the English literature and the first report to include the mammographic findings.

Show MeSH
Related in: MedlinePlus