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ProSplicer: a database of putative alternative splicing information derived from protein, mRNA and expressed sequence tag sequence data.

Huang HD, Horng JT, Lee CC, Liu BJ - Genome Biol. (2003)

Bottom Line: ProSplicer is a database of putative alternative splicing information derived from the alignment of proteins, mRNA sequences and expressed sequence tags (ESTs) against human genomic DNA sequences.Proteins, mRNA and ESTs provide valuable evidence that can reveal splice variants of genes.The alternative splicing information in the database can help users investigate the alternative splicing and tissue-specific expression of genes.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Computer Science and Information Engineering, National Central University, Jung-Li City 320, Taiwan.

ABSTRACT
ProSplicer is a database of putative alternative splicing information derived from the alignment of proteins, mRNA sequences and expressed sequence tags (ESTs) against human genomic DNA sequences. Proteins, mRNA and ESTs provide valuable evidence that can reveal splice variants of genes. The alternative splicing information in the database can help users investigate the alternative splicing and tissue-specific expression of genes.

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Related in: MedlinePlus

An example ProSplicer analysis showing how the three types of alternative splicing event will be displayed.
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Related In: Results  -  Collection


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Figure 2: An example ProSplicer analysis showing how the three types of alternative splicing event will be displayed.

Mentions: By considering the alternative splicing forms of a gene provided in ProSplicer, an exon might be left out or selected after comparison to other protein, mRNA or EST sequences. The three major types of alternative splicing events, including exon skipping, alternative 5' splicing donor sites, and alternative 3' splicing acceptor sites [6] are included in the database. Figure 1 shows an example of three types of alternative splicing events. The three types of alternative splicing forms can be shown directly in the graphical user interface in ProSplicer, as shown in Figure 2.


ProSplicer: a database of putative alternative splicing information derived from protein, mRNA and expressed sequence tag sequence data.

Huang HD, Horng JT, Lee CC, Liu BJ - Genome Biol. (2003)

An example ProSplicer analysis showing how the three types of alternative splicing event will be displayed.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC154580&req=5

Figure 2: An example ProSplicer analysis showing how the three types of alternative splicing event will be displayed.
Mentions: By considering the alternative splicing forms of a gene provided in ProSplicer, an exon might be left out or selected after comparison to other protein, mRNA or EST sequences. The three major types of alternative splicing events, including exon skipping, alternative 5' splicing donor sites, and alternative 3' splicing acceptor sites [6] are included in the database. Figure 1 shows an example of three types of alternative splicing events. The three types of alternative splicing forms can be shown directly in the graphical user interface in ProSplicer, as shown in Figure 2.

Bottom Line: ProSplicer is a database of putative alternative splicing information derived from the alignment of proteins, mRNA sequences and expressed sequence tags (ESTs) against human genomic DNA sequences.Proteins, mRNA and ESTs provide valuable evidence that can reveal splice variants of genes.The alternative splicing information in the database can help users investigate the alternative splicing and tissue-specific expression of genes.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Computer Science and Information Engineering, National Central University, Jung-Li City 320, Taiwan.

ABSTRACT
ProSplicer is a database of putative alternative splicing information derived from the alignment of proteins, mRNA sequences and expressed sequence tags (ESTs) against human genomic DNA sequences. Proteins, mRNA and ESTs provide valuable evidence that can reveal splice variants of genes. The alternative splicing information in the database can help users investigate the alternative splicing and tissue-specific expression of genes.

Show MeSH
Related in: MedlinePlus