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Percentile benchmarks in patients with rheumatoid arthritis: Health Assessment Questionnaire as a quality indicator (QI).

Krishnan E, Tugwell P, Fries JF - Arthritis Res. Ther. (2004)

Bottom Line: Few patients were treated with biologics.Percentile benchmarks allow disability outcomes to be compared and contrasted between different patient populations.Reference values for the HAQ-DI, presented here numerically and graphically, can be used in clinical practice as a QI measure to track functional disability outcomes and to measure response to therapy, and by arthritis patients in self-management programs.

View Article: PubMed Central - HTML - PubMed

Affiliation: Clinical Research Center of Reading, West Reading, PA, USA. Eswar_krishnan@hotmail.com

ABSTRACT
Physicians are in need of a simple objective, standardized tool to compare their patients with rheumatoid arthritis, as a group and individually, with national standards. The Disability Index of the Health Assessment Questionnaire (HAQ-DI) is a simple, robust tool that can fulfill these needs. However, use of this tool as a quality indicator (QI) is hampered by the unavailability of national reference values or benchmarks based on large, multicentric, heterogenous longitudinal patient cohorts. We utilized the 20-year longitudinal prospective data from 11 data banks of Arthritis Rheumatism and Aging Medical Information to calculate reference values for HAQ-DI. Overall, 6436 patients with rheumatoid arthritis were longitudinally followed for 32,324 person-years over the 20 years from 1981 to 2000. There were 64,647 HAQ-DI measurements, with an average of 19 measurements per person. Overall, 75% of patients were women and 89% were Caucasian; the median baseline age was 58.4 years and the median baseline HAQ-DI was 1.13. Few patients were treated with biologics. The HAQ-DI values had a Gaussian distribution except for the approximately 10% of observations showing no disability. Percentile benchmarks allow disability outcomes to be compared and contrasted between different patient populations. Reference values for the HAQ-DI, presented here numerically and graphically, can be used in clinical practice as a QI measure to track functional disability outcomes and to measure response to therapy, and by arthritis patients in self-management programs.

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Percentile Health Assessment Questionnaire (HAQ) Disability Index curves plotted for 4768 women with rheumatoid arthritis with 50,047 observations.
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Figure 4: Percentile Health Assessment Questionnaire (HAQ) Disability Index curves plotted for 4768 women with rheumatoid arthritis with 50,047 observations.

Mentions: The curves showing overall duration versus HAQ-DI, with 95% confidence bands (fitted using fractional polynomial modification of ordinary least squares regression), are shown in Fig. 2. Figures 3 and 4 show the percentile curves of HAQ-DI as a function of disease duration in strata of age and sex.


Percentile benchmarks in patients with rheumatoid arthritis: Health Assessment Questionnaire as a quality indicator (QI).

Krishnan E, Tugwell P, Fries JF - Arthritis Res. Ther. (2004)

Percentile Health Assessment Questionnaire (HAQ) Disability Index curves plotted for 4768 women with rheumatoid arthritis with 50,047 observations.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC1064863&req=5

Figure 4: Percentile Health Assessment Questionnaire (HAQ) Disability Index curves plotted for 4768 women with rheumatoid arthritis with 50,047 observations.
Mentions: The curves showing overall duration versus HAQ-DI, with 95% confidence bands (fitted using fractional polynomial modification of ordinary least squares regression), are shown in Fig. 2. Figures 3 and 4 show the percentile curves of HAQ-DI as a function of disease duration in strata of age and sex.

Bottom Line: Few patients were treated with biologics.Percentile benchmarks allow disability outcomes to be compared and contrasted between different patient populations.Reference values for the HAQ-DI, presented here numerically and graphically, can be used in clinical practice as a QI measure to track functional disability outcomes and to measure response to therapy, and by arthritis patients in self-management programs.

View Article: PubMed Central - HTML - PubMed

Affiliation: Clinical Research Center of Reading, West Reading, PA, USA. Eswar_krishnan@hotmail.com

ABSTRACT
Physicians are in need of a simple objective, standardized tool to compare their patients with rheumatoid arthritis, as a group and individually, with national standards. The Disability Index of the Health Assessment Questionnaire (HAQ-DI) is a simple, robust tool that can fulfill these needs. However, use of this tool as a quality indicator (QI) is hampered by the unavailability of national reference values or benchmarks based on large, multicentric, heterogenous longitudinal patient cohorts. We utilized the 20-year longitudinal prospective data from 11 data banks of Arthritis Rheumatism and Aging Medical Information to calculate reference values for HAQ-DI. Overall, 6436 patients with rheumatoid arthritis were longitudinally followed for 32,324 person-years over the 20 years from 1981 to 2000. There were 64,647 HAQ-DI measurements, with an average of 19 measurements per person. Overall, 75% of patients were women and 89% were Caucasian; the median baseline age was 58.4 years and the median baseline HAQ-DI was 1.13. Few patients were treated with biologics. The HAQ-DI values had a Gaussian distribution except for the approximately 10% of observations showing no disability. Percentile benchmarks allow disability outcomes to be compared and contrasted between different patient populations. Reference values for the HAQ-DI, presented here numerically and graphically, can be used in clinical practice as a QI measure to track functional disability outcomes and to measure response to therapy, and by arthritis patients in self-management programs.

Show MeSH
Related in: MedlinePlus