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Salvia columbariae contains tanshinones.

Adams JD, Wall M, Garcia C - Evid Based Complement Alternat Med (2005)

Bottom Line: Salvia columbariae (chia) was examined and found to contain miltionone II, cryptotanshinone and tanshinone IIA.These compounds may be of interest in the treatment of stroke and heart attack.

View Article: PubMed Central - PubMed

ABSTRACT
Salvia columbariae (chia) was examined and found to contain miltionone II, cryptotanshinone and tanshinone IIA. These compounds may be of interest in the treatment of stroke and heart attack.

No MeSH data available.


Related in: MedlinePlus

HPLC–MS total ion current, base peak current and 283 m/z ion current of a chia root extract. Peaks are: miltionone II (2.7 min), cryptotanshinone (6.3 min) and tanshinone IIA (12 min).
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fig3: HPLC–MS total ion current, base peak current and 283 m/z ion current of a chia root extract. Peaks are: miltionone II (2.7 min), cryptotanshinone (6.3 min) and tanshinone IIA (12 min).

Mentions: The root extracts were found to contain three major peaks on the HPLC system as visualized at 254 nm. The retention times were 4.2, 6.9 and 10.2 min. The UV spectra of each peak were similar with maxima at about 250 and 300 nm. The HPLC conditions were chosen based on the chromatography of tanshinones (5). The retention times were similar to published retention times for tanshinones (5). The UV spectra were similar to published spectra for miltionones, cryptotanshinone and related compounds (4). The extinction coefficients of tanshinone IIA are lambamaxMeoH nm (log epsilon): 220 (4.46), 250 (4.40) and 269 (4.44), (9). Based on the similar UV spectra and similar chromophores of the three compounds, the extinction coefficients are probably similar for each. The HPLC peaks for the three compounds integrated as follows: miltionone II (see below), 4.2 min 25.2%, cryptotanshinone, 6.9 min 69% and tanshinone IIA, 10.2 min 5.8%. The amounts of each compound in the 50 ml extract were: miltionone II, 0.7 μmol, cryptotanshinone, 2 μmol, and tanshinone IIA, 0.2 μmol. An HPLC–MS chromatogram is shown in Figure 3.


Salvia columbariae contains tanshinones.

Adams JD, Wall M, Garcia C - Evid Based Complement Alternat Med (2005)

HPLC–MS total ion current, base peak current and 283 m/z ion current of a chia root extract. Peaks are: miltionone II (2.7 min), cryptotanshinone (6.3 min) and tanshinone IIA (12 min).
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC1062160&req=5

fig3: HPLC–MS total ion current, base peak current and 283 m/z ion current of a chia root extract. Peaks are: miltionone II (2.7 min), cryptotanshinone (6.3 min) and tanshinone IIA (12 min).
Mentions: The root extracts were found to contain three major peaks on the HPLC system as visualized at 254 nm. The retention times were 4.2, 6.9 and 10.2 min. The UV spectra of each peak were similar with maxima at about 250 and 300 nm. The HPLC conditions were chosen based on the chromatography of tanshinones (5). The retention times were similar to published retention times for tanshinones (5). The UV spectra were similar to published spectra for miltionones, cryptotanshinone and related compounds (4). The extinction coefficients of tanshinone IIA are lambamaxMeoH nm (log epsilon): 220 (4.46), 250 (4.40) and 269 (4.44), (9). Based on the similar UV spectra and similar chromophores of the three compounds, the extinction coefficients are probably similar for each. The HPLC peaks for the three compounds integrated as follows: miltionone II (see below), 4.2 min 25.2%, cryptotanshinone, 6.9 min 69% and tanshinone IIA, 10.2 min 5.8%. The amounts of each compound in the 50 ml extract were: miltionone II, 0.7 μmol, cryptotanshinone, 2 μmol, and tanshinone IIA, 0.2 μmol. An HPLC–MS chromatogram is shown in Figure 3.

Bottom Line: Salvia columbariae (chia) was examined and found to contain miltionone II, cryptotanshinone and tanshinone IIA.These compounds may be of interest in the treatment of stroke and heart attack.

View Article: PubMed Central - PubMed

ABSTRACT
Salvia columbariae (chia) was examined and found to contain miltionone II, cryptotanshinone and tanshinone IIA. These compounds may be of interest in the treatment of stroke and heart attack.

No MeSH data available.


Related in: MedlinePlus