Limits...
Thuja occidentalis (Arbor vitae): A Review of its Pharmaceutical, Pharmacological and Clinical Properties.

Naser B, Bodinet C, Tegtmeier M, Lindequist U - Evid Based Complement Alternat Med (2005)

Bottom Line: Therefore, our aim was to search MEDLINE databases and survey manufacturers for further details or unpublished data.This review presents the botany, ethnobotany and phytochemistry, especially the different contents of essential oil (Thujone) in relation to different extraction procedures of this medicinal plant.Thuja's antiviral action and immunopharmacological potential, such as stimulatory and co-stimulatory effects on cytokine and antibody production and activation of macrophages and other immunocompetent cells, have been evaluated in numerous in vitro and in vivo investigations.

View Article: PubMed Central - PubMed

ABSTRACT
Arbor vitae (Thuja occidentalis L.) is a native European tree widely used in homeopathy and evidence-based phytotherapy. Many reviews and monographs have been published on the herbal substance's description, mode of action and clinical use. However, no comprehensive evidence-based review is available. Therefore, our aim was to search MEDLINE databases and survey manufacturers for further details or unpublished data. This review presents the botany, ethnobotany and phytochemistry, especially the different contents of essential oil (Thujone) in relation to different extraction procedures of this medicinal plant. Thuja's antiviral action and immunopharmacological potential, such as stimulatory and co-stimulatory effects on cytokine and antibody production and activation of macrophages and other immunocompetent cells, have been evaluated in numerous in vitro and in vivo investigations. Although no controlled trials have been conducted on Thuja occ alone, many clinical studies have been performed with a herbal medicinal product containing a special extract of Thuja occ and other immunostimulants, demonstrating its therapeutic efficacy and safety in respiratory tract infections.

No MeSH data available.


Related in: MedlinePlus

Thujone, which consists of 85% α-thujone and 15% β-thujone, is the major constituent in the essential oil from the dried herbal substance Thujae occidentalis herba.
© Copyright Policy
Related In: Results  -  Collection


getmorefigures.php?uid=PMC1062158&req=5

fig3: Thujone, which consists of 85% α-thujone and 15% β-thujone, is the major constituent in the essential oil from the dried herbal substance Thujae occidentalis herba.

Mentions: The constituents of the dried herbal substance Thujae occidentalis herba are listed in Table 2 (14,15,24–30). According to Hänsel et al. (15), the drug contains 1.4–4% essential oil, 60% of which is thujone, which corresponds to 2.4% thujone in the whole drug. Thujone occurs in nature as a mixture of α- and β-isomers (31,32). According to the European Agency for the Evaluation of Medicinal Products (EMEA), the content of thujone in dried twigs was determined as 7.6 mg/g, consisting of 85% α-thujone and 15% β-thujone (Fig. 3). The equilibrium mixture consists of 33% α-thujone and 67% β-thujone (27).


Thuja occidentalis (Arbor vitae): A Review of its Pharmaceutical, Pharmacological and Clinical Properties.

Naser B, Bodinet C, Tegtmeier M, Lindequist U - Evid Based Complement Alternat Med (2005)

Thujone, which consists of 85% α-thujone and 15% β-thujone, is the major constituent in the essential oil from the dried herbal substance Thujae occidentalis herba.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC1062158&req=5

fig3: Thujone, which consists of 85% α-thujone and 15% β-thujone, is the major constituent in the essential oil from the dried herbal substance Thujae occidentalis herba.
Mentions: The constituents of the dried herbal substance Thujae occidentalis herba are listed in Table 2 (14,15,24–30). According to Hänsel et al. (15), the drug contains 1.4–4% essential oil, 60% of which is thujone, which corresponds to 2.4% thujone in the whole drug. Thujone occurs in nature as a mixture of α- and β-isomers (31,32). According to the European Agency for the Evaluation of Medicinal Products (EMEA), the content of thujone in dried twigs was determined as 7.6 mg/g, consisting of 85% α-thujone and 15% β-thujone (Fig. 3). The equilibrium mixture consists of 33% α-thujone and 67% β-thujone (27).

Bottom Line: Therefore, our aim was to search MEDLINE databases and survey manufacturers for further details or unpublished data.This review presents the botany, ethnobotany and phytochemistry, especially the different contents of essential oil (Thujone) in relation to different extraction procedures of this medicinal plant.Thuja's antiviral action and immunopharmacological potential, such as stimulatory and co-stimulatory effects on cytokine and antibody production and activation of macrophages and other immunocompetent cells, have been evaluated in numerous in vitro and in vivo investigations.

View Article: PubMed Central - PubMed

ABSTRACT
Arbor vitae (Thuja occidentalis L.) is a native European tree widely used in homeopathy and evidence-based phytotherapy. Many reviews and monographs have been published on the herbal substance's description, mode of action and clinical use. However, no comprehensive evidence-based review is available. Therefore, our aim was to search MEDLINE databases and survey manufacturers for further details or unpublished data. This review presents the botany, ethnobotany and phytochemistry, especially the different contents of essential oil (Thujone) in relation to different extraction procedures of this medicinal plant. Thuja's antiviral action and immunopharmacological potential, such as stimulatory and co-stimulatory effects on cytokine and antibody production and activation of macrophages and other immunocompetent cells, have been evaluated in numerous in vitro and in vivo investigations. Although no controlled trials have been conducted on Thuja occ alone, many clinical studies have been performed with a herbal medicinal product containing a special extract of Thuja occ and other immunostimulants, demonstrating its therapeutic efficacy and safety in respiratory tract infections.

No MeSH data available.


Related in: MedlinePlus