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Metastatic Tumors

Nolan MRN - MedPix (2008)

View Article: MedPix Image - MedPix Topic

Affiliation: Uniformed Services University

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Development of metastatic deposits within the parenchyma of the brain is the result of hematogenous spread... On occasion, the nervous system may be the sole site of distant metastasis, but cerebral involvement is generally associated with spread from the primary source into many organs... Often superficially placed nodules in the cortex become adherent to the overlying dura without generalized dissemination into the subarachnoid space... Localized extension to the dura also occurs in metastatic lesions of the cerebellar cortex... Metastases occur in the deep gray nuclei of the cerebrum, in the brain stem and cerebellum, but are less common than in the cerebral hemispheres... In these locations they may develop either as part of extensive dissemination in the brain or as a solitary deposit... Mention should be made of the relation of metastatic tumors to the development of increased intracranial pressure... It is not uncommon, however, for the pathologist to find multiple secondary foci in patients who have presented no clinical manifestations of intracranial hypertension and whose brain at necropsy shows none of the anatomical alterations related to cerebral edema.

No MeSH data available.


Frontal Section through Hypothalamus: Section taken caudal to metastatic tumor from breast. There is intense edema of the white matter of the entire hemisphere. The cortical gray matter is poorly defined. The lateral ventricle is compressed by edema and the third ventricle is narrowed and displaced to the opposite side. This is included to show the appearance of the edematous region in the fresh state, for comparison with previous image.
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MPX2781_synpic42758: Frontal Section through Hypothalamus: Section taken caudal to metastatic tumor from breast. There is intense edema of the white matter of the entire hemisphere. The cortical gray matter is poorly defined. The lateral ventricle is compressed by edema and the third ventricle is narrowed and displaced to the opposite side. This is included to show the appearance of the edematous region in the fresh state, for comparison with previous image.


Metastatic Tumors

Nolan MRN - MedPix (2008)

Frontal Section through Hypothalamus: Section taken caudal to metastatic tumor from breast. There is intense edema of the white matter of the entire hemisphere. The cortical gray matter is poorly defined. The lateral ventricle is compressed by edema and the third ventricle is narrowed and displaced to the opposite side. This is included to show the appearance of the edematous region in the fresh state, for comparison with previous image.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=MPX2781&req=5

MPX2781_synpic42758: Frontal Section through Hypothalamus: Section taken caudal to metastatic tumor from breast. There is intense edema of the white matter of the entire hemisphere. The cortical gray matter is poorly defined. The lateral ventricle is compressed by edema and the third ventricle is narrowed and displaced to the opposite side. This is included to show the appearance of the edematous region in the fresh state, for comparison with previous image.

View Article: MedPix Image - MedPix Topic

Affiliation: Uniformed Services University

AUTOMATICALLY GENERATED EXCERPT
Please rate it.

Development of metastatic deposits within the parenchyma of the brain is the result of hematogenous spread... On occasion, the nervous system may be the sole site of distant metastasis, but cerebral involvement is generally associated with spread from the primary source into many organs... Often superficially placed nodules in the cortex become adherent to the overlying dura without generalized dissemination into the subarachnoid space... Localized extension to the dura also occurs in metastatic lesions of the cerebellar cortex... Metastases occur in the deep gray nuclei of the cerebrum, in the brain stem and cerebellum, but are less common than in the cerebral hemispheres... In these locations they may develop either as part of extensive dissemination in the brain or as a solitary deposit... Mention should be made of the relation of metastatic tumors to the development of increased intracranial pressure... It is not uncommon, however, for the pathologist to find multiple secondary foci in patients who have presented no clinical manifestations of intracranial hypertension and whose brain at necropsy shows none of the anatomical alterations related to cerebral edema.

No MeSH data available.