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Metastatic Tumors

Nolan MRN - MedPix (2008)

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Affiliation: Uniformed Services University

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Development of metastatic deposits within the parenchyma of the brain is the result of hematogenous spread... On occasion, the nervous system may be the sole site of distant metastasis, but cerebral involvement is generally associated with spread from the primary source into many organs... Often superficially placed nodules in the cortex become adherent to the overlying dura without generalized dissemination into the subarachnoid space... Localized extension to the dura also occurs in metastatic lesions of the cerebellar cortex... Metastases occur in the deep gray nuclei of the cerebrum, in the brain stem and cerebellum, but are less common than in the cerebral hemispheres... In these locations they may develop either as part of extensive dissemination in the brain or as a solitary deposit... Mention should be made of the relation of metastatic tumors to the development of increased intracranial pressure... It is not uncommon, however, for the pathologist to find multiple secondary foci in patients who have presented no clinical manifestations of intracranial hypertension and whose brain at necropsy shows none of the anatomical alterations related to cerebral edema.

No MeSH data available.


Frontal Section Brain through Anterior Limb of Internal Capsule: Hematogenous dissemination of metastatic melanoma. Note that all deposits lie within the cortex and subcortical white matter. Primary in skin.
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MPX2781_synpic42753: Frontal Section Brain through Anterior Limb of Internal Capsule: Hematogenous dissemination of metastatic melanoma. Note that all deposits lie within the cortex and subcortical white matter. Primary in skin.


Metastatic Tumors

Nolan MRN - MedPix (2008)

Frontal Section Brain through Anterior Limb of Internal Capsule: Hematogenous dissemination of metastatic melanoma. Note that all deposits lie within the cortex and subcortical white matter. Primary in skin.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=MPX2781&req=5

MPX2781_synpic42753: Frontal Section Brain through Anterior Limb of Internal Capsule: Hematogenous dissemination of metastatic melanoma. Note that all deposits lie within the cortex and subcortical white matter. Primary in skin.

View Article: MedPix Image - MedPix Topic

Affiliation: Uniformed Services University

AUTOMATICALLY GENERATED EXCERPT
Please rate it.

Development of metastatic deposits within the parenchyma of the brain is the result of hematogenous spread... On occasion, the nervous system may be the sole site of distant metastasis, but cerebral involvement is generally associated with spread from the primary source into many organs... Often superficially placed nodules in the cortex become adherent to the overlying dura without generalized dissemination into the subarachnoid space... Localized extension to the dura also occurs in metastatic lesions of the cerebellar cortex... Metastases occur in the deep gray nuclei of the cerebrum, in the brain stem and cerebellum, but are less common than in the cerebral hemispheres... In these locations they may develop either as part of extensive dissemination in the brain or as a solitary deposit... Mention should be made of the relation of metastatic tumors to the development of increased intracranial pressure... It is not uncommon, however, for the pathologist to find multiple secondary foci in patients who have presented no clinical manifestations of intracranial hypertension and whose brain at necropsy shows none of the anatomical alterations related to cerebral edema.

No MeSH data available.