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Metastatic Tumors

Nolan MRN - MedPix (2008)

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Affiliation: Uniformed Services University

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Development of metastatic deposits within the parenchyma of the brain is the result of hematogenous spread... On occasion, the nervous system may be the sole site of distant metastasis, but cerebral involvement is generally associated with spread from the primary source into many organs... Often superficially placed nodules in the cortex become adherent to the overlying dura without generalized dissemination into the subarachnoid space... Localized extension to the dura also occurs in metastatic lesions of the cerebellar cortex... Metastases occur in the deep gray nuclei of the cerebrum, in the brain stem and cerebellum, but are less common than in the cerebral hemispheres... In these locations they may develop either as part of extensive dissemination in the brain or as a solitary deposit... Mention should be made of the relation of metastatic tumors to the development of increased intracranial pressure... It is not uncommon, however, for the pathologist to find multiple secondary foci in patients who have presented no clinical manifestations of intracranial hypertension and whose brain at necropsy shows none of the anatomical alterations related to cerebral edema.

No MeSH data available.


Calvarium with Attached Dura: The entire subdural surface is covered with a sheet of carcinoma (tumor en plaque) in which larger discrete nodules are embedded. The nodules indent the underlying cortex but do not penetrate the subarachnoid space. Primary carcinoma of the prostate with widespread dissemination.
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MPX2781_synpic42748: Calvarium with Attached Dura: The entire subdural surface is covered with a sheet of carcinoma (tumor en plaque) in which larger discrete nodules are embedded. The nodules indent the underlying cortex but do not penetrate the subarachnoid space. Primary carcinoma of the prostate with widespread dissemination.


Metastatic Tumors

Nolan MRN - MedPix (2008)

Calvarium with Attached Dura: The entire subdural surface is covered with a sheet of carcinoma (tumor en plaque) in which larger discrete nodules are embedded. The nodules indent the underlying cortex but do not penetrate the subarachnoid space. Primary carcinoma of the prostate with widespread dissemination.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=MPX2781&req=5

MPX2781_synpic42748: Calvarium with Attached Dura: The entire subdural surface is covered with a sheet of carcinoma (tumor en plaque) in which larger discrete nodules are embedded. The nodules indent the underlying cortex but do not penetrate the subarachnoid space. Primary carcinoma of the prostate with widespread dissemination.

View Article: MedPix Image - MedPix Topic

Affiliation: Uniformed Services University

AUTOMATICALLY GENERATED EXCERPT
Please rate it.

Development of metastatic deposits within the parenchyma of the brain is the result of hematogenous spread... On occasion, the nervous system may be the sole site of distant metastasis, but cerebral involvement is generally associated with spread from the primary source into many organs... Often superficially placed nodules in the cortex become adherent to the overlying dura without generalized dissemination into the subarachnoid space... Localized extension to the dura also occurs in metastatic lesions of the cerebellar cortex... Metastases occur in the deep gray nuclei of the cerebrum, in the brain stem and cerebellum, but are less common than in the cerebral hemispheres... In these locations they may develop either as part of extensive dissemination in the brain or as a solitary deposit... Mention should be made of the relation of metastatic tumors to the development of increased intracranial pressure... It is not uncommon, however, for the pathologist to find multiple secondary foci in patients who have presented no clinical manifestations of intracranial hypertension and whose brain at necropsy shows none of the anatomical alterations related to cerebral edema.

No MeSH data available.