Limits...
Glioma: Glioblastoma Multiforme

Nolan MRN - MedPix (2008)

View Article: MedPix Image - MedPix Topic

Affiliation: Uniformed Services University

ABSTRACT

The term glioblastoma multiforme is here used for those tumors of astrocytic origin which are rapidly growing; that is, Kernohan’s grades III and IV. The gloiblastoma multiforme is very frequent form of glioma and is most characteristically seen in the cerebrum of adults. It is distinctly uncommon in children and, when it does occur below the age of 20, it is usually found in the cerebellum or brain stem, sites where this tumor is rare in adults. As glioblastomas evolve, an apparently circumscribed mass usually develops, with deformation of adjacent structures. Microscopic examination, however, shows that tumor cells have extended beyond the zone of gross involvement. Some examples infiltrate the brain parenchyma without complete destruction of tissue or the formation of a compact mass. Extension across the midline occurs in many instances. Dural attachment and local meningeal spread have already been commented upon. Implantations take place on the ependymal surfaces rather frequently and occasionally in the subarachnoid space, through these seldom attain large size. The multiform appearance of the cut surface results from degenerative changes-hemorrhage, necrosis and cyst formation-to which this glioma is especially prone.

No MeSH data available.


Frontal Section of Brain through Genu of Callosum:  A large hemispheric glioblastoma has extended to involve the corpus callousum. At this level, there appear to be two tumors but a connection was demonstrated in sections more anteriorly.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=MPX2759&req=5

MPX2759_synpic42621: Frontal Section of Brain through Genu of Callosum: A large hemispheric glioblastoma has extended to involve the corpus callousum. At this level, there appear to be two tumors but a connection was demonstrated in sections more anteriorly.


Glioma: Glioblastoma Multiforme

Nolan MRN - MedPix (2008)

Frontal Section of Brain through Genu of Callosum:  A large hemispheric glioblastoma has extended to involve the corpus callousum. At this level, there appear to be two tumors but a connection was demonstrated in sections more anteriorly.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=MPX2759&req=5

MPX2759_synpic42621: Frontal Section of Brain through Genu of Callosum: A large hemispheric glioblastoma has extended to involve the corpus callousum. At this level, there appear to be two tumors but a connection was demonstrated in sections more anteriorly.

View Article: MedPix Image - MedPix Topic

Affiliation: Uniformed Services University

ABSTRACT

The term glioblastoma multiforme is here used for those tumors of astrocytic origin which are rapidly growing; that is, Kernohan’s grades III and IV. The gloiblastoma multiforme is very frequent form of glioma and is most characteristically seen in the cerebrum of adults. It is distinctly uncommon in children and, when it does occur below the age of 20, it is usually found in the cerebellum or brain stem, sites where this tumor is rare in adults. As glioblastomas evolve, an apparently circumscribed mass usually develops, with deformation of adjacent structures. Microscopic examination, however, shows that tumor cells have extended beyond the zone of gross involvement. Some examples infiltrate the brain parenchyma without complete destruction of tissue or the formation of a compact mass. Extension across the midline occurs in many instances. Dural attachment and local meningeal spread have already been commented upon. Implantations take place on the ependymal surfaces rather frequently and occasionally in the subarachnoid space, through these seldom attain large size. The multiform appearance of the cut surface results from degenerative changes-hemorrhage, necrosis and cyst formation-to which this glioma is especially prone.

No MeSH data available.