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Graves' Disease

Nieves NMN - MedPix (2001)

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Affiliation: Tripler Army Medical Center

ABSTRACT

Clinical History: 45 year old female with suppressed TSH and elevated free T4. Has had approximately 25 pound weight loss within the last five months. Clinically suspect Graves' Disease. Findings: Thyroid uptakes and scan utilizing 247 microCuries of 123- Iodine Sodium administered orally. (May administer 200-300 micro Curies). Four hour uptakes were calculated at 43% (Normal range 5-15%), which is elevated. Twenty four hour uptakes were calculated at 62% (Normal range 15-30%), which is elevated. Static images of the thyroid obtained in the anterior, RAO, and LAO projections show uniform distribution of the radiopharmaceutical throughout both lobes of the thyroid. Visually, thyroid radiotracer uptake is increased, and there is little background activity. There is no evidence of cold nodule or any other abnormality. The thyroid gland was palpated and was enlarged to approximately twice the normal size. Discussion: Thyroid scintigraphy may be performed with 99mTc pertechnetate, 123 Iodine, or 131 Iodine. However, 123 Iodine and 99m Tc pertechnetate are the preferred radiopharmaceuticals for thyroid imaging. The advantage of imaging with 123 Iodine is that thyroid uptakes can be calculated. Graves' disease, or diffuse toxic goiter, is thought to be due to an autoimmune etiology. On scintigraphy, the thyroid gland will show homogenously increased radiotracer uptake, with little background activity. Ocassionally, the pyramidal lobe will be demonstrated. Patients can be offered 131 Iodine for treatment of Graves' disease. Text added by Neris Nieves

No MeSH data available.


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Graves' Disease

Nieves NMN - MedPix (2001)

© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=MPX2723&req=5

View Article: MedPix Image - MedPix Topic

Affiliation: Tripler Army Medical Center

ABSTRACT

Clinical History: 45 year old female with suppressed TSH and elevated free T4. Has had approximately 25 pound weight loss within the last five months. Clinically suspect Graves' Disease. Findings: Thyroid uptakes and scan utilizing 247 microCuries of 123- Iodine Sodium administered orally. (May administer 200-300 micro Curies). Four hour uptakes were calculated at 43% (Normal range 5-15%), which is elevated. Twenty four hour uptakes were calculated at 62% (Normal range 15-30%), which is elevated. Static images of the thyroid obtained in the anterior, RAO, and LAO projections show uniform distribution of the radiopharmaceutical throughout both lobes of the thyroid. Visually, thyroid radiotracer uptake is increased, and there is little background activity. There is no evidence of cold nodule or any other abnormality. The thyroid gland was palpated and was enlarged to approximately twice the normal size. Discussion: Thyroid scintigraphy may be performed with 99mTc pertechnetate, 123 Iodine, or 131 Iodine. However, 123 Iodine and 99m Tc pertechnetate are the preferred radiopharmaceuticals for thyroid imaging. The advantage of imaging with 123 Iodine is that thyroid uptakes can be calculated. Graves' disease, or diffuse toxic goiter, is thought to be due to an autoimmune etiology. On scintigraphy, the thyroid gland will show homogenously increased radiotracer uptake, with little background activity. Ocassionally, the pyramidal lobe will be demonstrated. Patients can be offered 131 Iodine for treatment of Graves' disease. Text added by Neris Nieves

No MeSH data available.