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Mucinous Cystic Neoplasm of the Pancreas

Simays, MD AESM - MedPix (2001)

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Affiliation: Naval Medical Center San Diego

ABSTRACT

Mucinous Csytic Neoplasm of the Pancreas; AKA-macrocystic adenoma, mucinous cystadenoma, cystadenocarcinoma. Frequency- 10% of pancreatic cysts, 1% of pancreatic neoplasms Mean Age- 50 years ( 20-95 ), 50% between 40-60 years old M:F 1:19 Pathology: Large smooth round/lobulated multiloculated cystic mass encapsulated by a layer of fibrous connective tissue Histology: similar to biliary and ovarian mucinous tumors; cysts lined by tall columnar, mucin-producing cells subtended by a densely cellular mesenchymal stroma (reminiscent of ovarian stroma), often in papillary arrangement Location: often in the tail (90%), body, infrequently in head -well-demarcated thick-walled mass, mean 10-12 cm -multi/unilocular large cyss >2 cm with thin septa <2 mm * a tumor with <6 cysts of >2 cm in diameter is in 93-95% a mucinous cystic neoplasm -amorphous discontinuous peripheral mural calcifications (10-15%) -solid papillary excresences protrude into the interior of the tumor -hypovascular mass with sparse neovascularity -great propensity for invasion of adjacent organs U/S: -cysts may contain low level echoes; echogenic mural calcifications if present CT: -internal septations may not be seen without contrast enhancement; cysts with HU of water, different cysts with different HU's; enhance of cyst walls MRI: -high T2 from mucinous component Angio: -predominantly avascular mass, small area of blush in cyst wall and solid components, mass effect on adjacent arteries and veins by cysts Mets: -round thick walled cystic lesions in the liver Prognosis: -invariable transformation into cystadenocarcinoma Rx: -complete surgical excision, 5 yr survival is 74-90% DDx: pseudocyst, lymphangioma/hemangioma, variants of ductal adenocarcinoma, solid and cystic papillary epithelioid neoplasm, cystic islet cell tumor, cystic met, atypical serous cystadenoma, sarcoma, infection (amebiasis, echinococcus0

No MeSH data available.


peripheral enhancement
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MPX2722_synpic2905: peripheral enhancement


Mucinous Cystic Neoplasm of the Pancreas

Simays, MD AESM - MedPix (2001)

peripheral enhancement
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=MPX2722&req=5

MPX2722_synpic2905: peripheral enhancement

View Article: MedPix Image - MedPix Topic

Affiliation: Naval Medical Center San Diego

ABSTRACT

Mucinous Csytic Neoplasm of the Pancreas; AKA-macrocystic adenoma, mucinous cystadenoma, cystadenocarcinoma. Frequency- 10% of pancreatic cysts, 1% of pancreatic neoplasms Mean Age- 50 years ( 20-95 ), 50% between 40-60 years old M:F 1:19 Pathology: Large smooth round/lobulated multiloculated cystic mass encapsulated by a layer of fibrous connective tissue Histology: similar to biliary and ovarian mucinous tumors; cysts lined by tall columnar, mucin-producing cells subtended by a densely cellular mesenchymal stroma (reminiscent of ovarian stroma), often in papillary arrangement Location: often in the tail (90%), body, infrequently in head -well-demarcated thick-walled mass, mean 10-12 cm -multi/unilocular large cyss >2 cm with thin septa <2 mm * a tumor with <6 cysts of >2 cm in diameter is in 93-95% a mucinous cystic neoplasm -amorphous discontinuous peripheral mural calcifications (10-15%) -solid papillary excresences protrude into the interior of the tumor -hypovascular mass with sparse neovascularity -great propensity for invasion of adjacent organs U/S: -cysts may contain low level echoes; echogenic mural calcifications if present CT: -internal septations may not be seen without contrast enhancement; cysts with HU of water, different cysts with different HU's; enhance of cyst walls MRI: -high T2 from mucinous component Angio: -predominantly avascular mass, small area of blush in cyst wall and solid components, mass effect on adjacent arteries and veins by cysts Mets: -round thick walled cystic lesions in the liver Prognosis: -invariable transformation into cystadenocarcinoma Rx: -complete surgical excision, 5 yr survival is 74-90% DDx: pseudocyst, lymphangioma/hemangioma, variants of ductal adenocarcinoma, solid and cystic papillary epithelioid neoplasm, cystic islet cell tumor, cystic met, atypical serous cystadenoma, sarcoma, infection (amebiasis, echinococcus0

No MeSH data available.