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Cowden's Syndrome

Perry AVP - MedPix (2010)

View Article: MedPix Image - MedPix Case

Affiliation: Uniformed Services University

ABSTRACT

Diagnosis: Cowden's Syndrome

History: 48y/o female with history of bilateral breast cancer s/p bilateral mastectomy who is currently hospitalized after obtaining bronchoscopy to evaluate multiple pulmonary nodules.

Findings: CXR: hypoinflation of lungs, increased pulmonary vascular markings throughout bilateral lung fields, multiple pulmonary nodules with the most prominent in the right lower lobe, mild cardiomegaly, lack of breast shadows bilaterally, fluid withing the right major and minor fissure. CT of Chest/ABD/Pelvis: Diffuse thyroid enlargement with nodule present in the left lobe, multiple large (>5mm) pulmonary nodules throughout both lungs, bilateral myelolipomas with L larger than R.

Ddx: Cowden's Syndrome Li-Fraumeni Syndrome Peutz-Jeghers Syndrome BRCA1/2 Ataxia-Telangiectasia Syndrome

Dxhow: Genetic Testing

Exam: Physical exam shows thyroid enlargement with prominent left sided nodules as well as bilateral mastectomy.

No MeSH data available.


PA view shows hypoinflated lungs with increased pulmonary markings throughout all lung fields.  Multiple pulmonary nodules are appreciated with the largest present in the right lower lobe.  Breast shadows are absent bilaterally.  Fluid is present in the right major and minor fissures but no blunting of costophrenic angles.
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MPX2355_synpic52989: PA view shows hypoinflated lungs with increased pulmonary markings throughout all lung fields. Multiple pulmonary nodules are appreciated with the largest present in the right lower lobe. Breast shadows are absent bilaterally. Fluid is present in the right major and minor fissures but no blunting of costophrenic angles.


Cowden's Syndrome

Perry AVP - MedPix (2010)

PA view shows hypoinflated lungs with increased pulmonary markings throughout all lung fields.  Multiple pulmonary nodules are appreciated with the largest present in the right lower lobe.  Breast shadows are absent bilaterally.  Fluid is present in the right major and minor fissures but no blunting of costophrenic angles.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=MPX2355&req=5

MPX2355_synpic52989: PA view shows hypoinflated lungs with increased pulmonary markings throughout all lung fields. Multiple pulmonary nodules are appreciated with the largest present in the right lower lobe. Breast shadows are absent bilaterally. Fluid is present in the right major and minor fissures but no blunting of costophrenic angles.

View Article: MedPix Image - MedPix Case

Affiliation: Uniformed Services University

ABSTRACT

Diagnosis: Cowden's Syndrome

History: 48y/o female with history of bilateral breast cancer s/p bilateral mastectomy who is currently hospitalized after obtaining bronchoscopy to evaluate multiple pulmonary nodules.

Findings: CXR: hypoinflation of lungs, increased pulmonary vascular markings throughout bilateral lung fields, multiple pulmonary nodules with the most prominent in the right lower lobe, mild cardiomegaly, lack of breast shadows bilaterally, fluid withing the right major and minor fissure. CT of Chest/ABD/Pelvis: Diffuse thyroid enlargement with nodule present in the left lobe, multiple large (>5mm) pulmonary nodules throughout both lungs, bilateral myelolipomas with L larger than R.

Ddx: Cowden's Syndrome Li-Fraumeni Syndrome Peutz-Jeghers Syndrome BRCA1/2 Ataxia-Telangiectasia Syndrome

Dxhow: Genetic Testing

Exam: Physical exam shows thyroid enlargement with prominent left sided nodules as well as bilateral mastectomy.

No MeSH data available.