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Anaplastic astrocytoma - WHO Grade 3

USU Teaching File MUTF - MedPix

View Article: MedPix Image - MedPix Case

Affiliation: Uniformed Services University

ABSTRACT

Diagnosis: Anaplastic astrocytoma - WHO Grade 3

History: 28 yo c/o right leg weakness. He denies headaches, nausea, vomiting, or vision changes. Currently complains of right leg weakness, slight sensory decrease and, and possible difficulty talking.

Findings: MRI w/ contrast: Within the L cerebral hemisphere, in the frontoparietal region, there is marked increased white matter signal throughout, with a mild amount of midline shift of the falx. Posteriorly in this region there is a cystic lesion that does not enhance. The largest single cyst measures approximately 6mm, with the overall largest size of the cluster of cysts measuring 10mm. There is also an extensive amount of edema, and at the area of midline shift of the falx, there is some increased white matter signal in the right hemisphere which may represent tumoral extension across the corpus colosum. There is some edema and effacement of the cerebral sulci on the left at the level of the lesion. The remaining soft tissues are unremarkable.

Ddx: High-grade astrocytoma, oligodendroglial tumor, mixed glioma, ependymal tumor, infarction, or metastasis

Exam: vitals: HR 67, BP 139/82, RR 16, Temp 97.6 140/ 104/ 13 <118 15.1>15.9/47<240gen: wn, wd, alert and oriented x3 3.8/ 25 / 0.9 heent: normocephalic, supple w/o masses, perlapulm: equal breath sounds, no rales, rhonchi, wheezes Mg 1.9, PT 14.7, PTT 28heart: RRR, no murmurs, rubs, or gallopsabd: soft, nt, nd, normal BS, no organomegalyneuro: AAOx3, CN 2-12 intact, motor: R 4/5 in delt, biceps, triceps, quad; 2/5 in extensor hallucis longus, Achilles, and gluteus L 5/5 throughout sensory: slight decrease in light touch in right lower extremity throughout reflex: 3+ R Achilles, R patella, 5 beat clonus, up toe 2+ L Achilles, L patella, no clonus, down toe cerebellar: intact with finger-to-noseext: right shin with multiple abrasions, no clubbing, cyanosis, or edema; good pulses throughout

No MeSH data available.


MRI w/ contrast: Within the L cerebral hemisphere, in the frontoparietal region, there is marked increased white matter signal throughout, with a mild amount of midline shift of the falx.  Posteriorly in this region there is a cystic lesion that does not enhance.  The largest single cyst measures approximately 6mm, with the overall largest size of the cluster of cysts measuring 10mm.  There is also an extensive amount of edema, and at the area of midline shift of the falx, there is some increased white matter signal in the right hemisphere which may represent tumoral extension across the corpus colosum.  There is some edema and effacement of the cerebral sulci on the left at the level of the lesion.  The remaining soft tissues are unremarkable.
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MPX2185_synpic16674: MRI w/ contrast: Within the L cerebral hemisphere, in the frontoparietal region, there is marked increased white matter signal throughout, with a mild amount of midline shift of the falx. Posteriorly in this region there is a cystic lesion that does not enhance. The largest single cyst measures approximately 6mm, with the overall largest size of the cluster of cysts measuring 10mm. There is also an extensive amount of edema, and at the area of midline shift of the falx, there is some increased white matter signal in the right hemisphere which may represent tumoral extension across the corpus colosum. There is some edema and effacement of the cerebral sulci on the left at the level of the lesion. The remaining soft tissues are unremarkable.


Anaplastic astrocytoma - WHO Grade 3

USU Teaching File MUTF - MedPix

MRI w/ contrast: Within the L cerebral hemisphere, in the frontoparietal region, there is marked increased white matter signal throughout, with a mild amount of midline shift of the falx.  Posteriorly in this region there is a cystic lesion that does not enhance.  The largest single cyst measures approximately 6mm, with the overall largest size of the cluster of cysts measuring 10mm.  There is also an extensive amount of edema, and at the area of midline shift of the falx, there is some increased white matter signal in the right hemisphere which may represent tumoral extension across the corpus colosum.  There is some edema and effacement of the cerebral sulci on the left at the level of the lesion.  The remaining soft tissues are unremarkable.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=MPX2185&req=5

MPX2185_synpic16674: MRI w/ contrast: Within the L cerebral hemisphere, in the frontoparietal region, there is marked increased white matter signal throughout, with a mild amount of midline shift of the falx. Posteriorly in this region there is a cystic lesion that does not enhance. The largest single cyst measures approximately 6mm, with the overall largest size of the cluster of cysts measuring 10mm. There is also an extensive amount of edema, and at the area of midline shift of the falx, there is some increased white matter signal in the right hemisphere which may represent tumoral extension across the corpus colosum. There is some edema and effacement of the cerebral sulci on the left at the level of the lesion. The remaining soft tissues are unremarkable.

View Article: MedPix Image - MedPix Case

Affiliation: Uniformed Services University

ABSTRACT

Diagnosis: Anaplastic astrocytoma - WHO Grade 3

History: 28 yo c/o right leg weakness. He denies headaches, nausea, vomiting, or vision changes. Currently complains of right leg weakness, slight sensory decrease and, and possible difficulty talking.

Findings: MRI w/ contrast: Within the L cerebral hemisphere, in the frontoparietal region, there is marked increased white matter signal throughout, with a mild amount of midline shift of the falx. Posteriorly in this region there is a cystic lesion that does not enhance. The largest single cyst measures approximately 6mm, with the overall largest size of the cluster of cysts measuring 10mm. There is also an extensive amount of edema, and at the area of midline shift of the falx, there is some increased white matter signal in the right hemisphere which may represent tumoral extension across the corpus colosum. There is some edema and effacement of the cerebral sulci on the left at the level of the lesion. The remaining soft tissues are unremarkable.

Ddx: High-grade astrocytoma, oligodendroglial tumor, mixed glioma, ependymal tumor, infarction, or metastasis

Exam: vitals: HR 67, BP 139/82, RR 16, Temp 97.6 140/ 104/ 13 <118 15.1>15.9/47<240gen: wn, wd, alert and oriented x3 3.8/ 25 / 0.9 heent: normocephalic, supple w/o masses, perlapulm: equal breath sounds, no rales, rhonchi, wheezes Mg 1.9, PT 14.7, PTT 28heart: RRR, no murmurs, rubs, or gallopsabd: soft, nt, nd, normal BS, no organomegalyneuro: AAOx3, CN 2-12 intact, motor: R 4/5 in delt, biceps, triceps, quad; 2/5 in extensor hallucis longus, Achilles, and gluteus L 5/5 throughout sensory: slight decrease in light touch in right lower extremity throughout reflex: 3+ R Achilles, R patella, 5 beat clonus, up toe 2+ L Achilles, L patella, no clonus, down toe cerebellar: intact with finger-to-noseext: right shin with multiple abrasions, no clubbing, cyanosis, or edema; good pulses throughout

No MeSH data available.