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Chondrosarcoma metastatic to Brain

Smith ABS - MedPix (2008)

View Article: MedPix Image - MedPix Case

Affiliation: Uniformed Services University

ABSTRACT

Diagnosis: Chondrosarcoma metastatic to Brain

History: 55 yo woman with history of a resected left lower extremity chondrosarcoma. Known to have lung metastases, she presents now with right upper and lower extremity weakness.

Findings: Multiple lesions within the brain. The most prominent were in the left frontal and parietal region. The lesions were very hyperintense on T2, and demonstrated only peripheral enhancement

Ddx: Given the marked hyperintensity on T2 and history of chondrosarcoma, this is the most likely diagnosis. Metastases from other locations could also be in the differential.

Dxhow: Biopsy and Histology

Exam: Weakness in both upper and lower extremities, right greater than left.

No MeSH data available.


Histology reveals normal brain tissue adjacent to a chondroid matrix consistent with metastatic chondrosarcoma.  Notice the sharp demarcation between the tumor and the brain.  Metastases usually have a "pushing margin" like this - very different from the indistinct and infiltrating border of a glioma or lymphoma.
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MPX2084_synpic40683: Histology reveals normal brain tissue adjacent to a chondroid matrix consistent with metastatic chondrosarcoma. Notice the sharp demarcation between the tumor and the brain. Metastases usually have a "pushing margin" like this - very different from the indistinct and infiltrating border of a glioma or lymphoma.


Chondrosarcoma metastatic to Brain

Smith ABS - MedPix (2008)

Histology reveals normal brain tissue adjacent to a chondroid matrix consistent with metastatic chondrosarcoma.  Notice the sharp demarcation between the tumor and the brain.  Metastases usually have a "pushing margin" like this - very different from the indistinct and infiltrating border of a glioma or lymphoma.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=MPX2084&req=5

MPX2084_synpic40683: Histology reveals normal brain tissue adjacent to a chondroid matrix consistent with metastatic chondrosarcoma. Notice the sharp demarcation between the tumor and the brain. Metastases usually have a "pushing margin" like this - very different from the indistinct and infiltrating border of a glioma or lymphoma.

View Article: MedPix Image - MedPix Case

Affiliation: Uniformed Services University

ABSTRACT

Diagnosis: Chondrosarcoma metastatic to Brain

History: 55 yo woman with history of a resected left lower extremity chondrosarcoma. Known to have lung metastases, she presents now with right upper and lower extremity weakness.

Findings: Multiple lesions within the brain. The most prominent were in the left frontal and parietal region. The lesions were very hyperintense on T2, and demonstrated only peripheral enhancement

Ddx: Given the marked hyperintensity on T2 and history of chondrosarcoma, this is the most likely diagnosis. Metastases from other locations could also be in the differential.

Dxhow: Biopsy and Histology

Exam: Weakness in both upper and lower extremities, right greater than left.

No MeSH data available.