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Chondrosarcoma metastatic to Brain

Smith ABS - MedPix (2008)

View Article: MedPix Image - MedPix Case

Affiliation: Uniformed Services University

ABSTRACT

Diagnosis: Chondrosarcoma metastatic to Brain

History: 55 yo woman with history of a resected left lower extremity chondrosarcoma. Known to have lung metastases, she presents now with right upper and lower extremity weakness.

Findings: Multiple lesions within the brain. The most prominent were in the left frontal and parietal region. The lesions were very hyperintense on T2, and demonstrated only peripheral enhancement

Ddx: Given the marked hyperintensity on T2 and history of chondrosarcoma, this is the most likely diagnosis. Metastases from other locations could also be in the differential.

Dxhow: Biopsy and Histology

Exam: Weakness in both upper and lower extremities, right greater than left.

No MeSH data available.


T1 and T2 weighted images demonstrate two prominent lesions that demonstrate T1 and T2 prolongation.  The larger lesion is in the left parietal and has a lobulated contour.  The smaller lesion is in the left frontal lobe.  On post contrast imaging the periphery of the lesions enhance.  Histology reveals normal brain tissue adjacent to a chondroid matrix consistent with metastatic chondrosarcoma.  The patient's primary lesion was in his leg and he also had metastases to the lungs.
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MPX2084_synpic40680: T1 and T2 weighted images demonstrate two prominent lesions that demonstrate T1 and T2 prolongation. The larger lesion is in the left parietal and has a lobulated contour. The smaller lesion is in the left frontal lobe. On post contrast imaging the periphery of the lesions enhance. Histology reveals normal brain tissue adjacent to a chondroid matrix consistent with metastatic chondrosarcoma. The patient's primary lesion was in his leg and he also had metastases to the lungs.


Chondrosarcoma metastatic to Brain

Smith ABS - MedPix (2008)

T1 and T2 weighted images demonstrate two prominent lesions that demonstrate T1 and T2 prolongation.  The larger lesion is in the left parietal and has a lobulated contour.  The smaller lesion is in the left frontal lobe.  On post contrast imaging the periphery of the lesions enhance.  Histology reveals normal brain tissue adjacent to a chondroid matrix consistent with metastatic chondrosarcoma.  The patient's primary lesion was in his leg and he also had metastases to the lungs.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=MPX2084&req=5

MPX2084_synpic40680: T1 and T2 weighted images demonstrate two prominent lesions that demonstrate T1 and T2 prolongation. The larger lesion is in the left parietal and has a lobulated contour. The smaller lesion is in the left frontal lobe. On post contrast imaging the periphery of the lesions enhance. Histology reveals normal brain tissue adjacent to a chondroid matrix consistent with metastatic chondrosarcoma. The patient's primary lesion was in his leg and he also had metastases to the lungs.

View Article: MedPix Image - MedPix Case

Affiliation: Uniformed Services University

ABSTRACT

Diagnosis: Chondrosarcoma metastatic to Brain

History: 55 yo woman with history of a resected left lower extremity chondrosarcoma. Known to have lung metastases, she presents now with right upper and lower extremity weakness.

Findings: Multiple lesions within the brain. The most prominent were in the left frontal and parietal region. The lesions were very hyperintense on T2, and demonstrated only peripheral enhancement

Ddx: Given the marked hyperintensity on T2 and history of chondrosarcoma, this is the most likely diagnosis. Metastases from other locations could also be in the differential.

Dxhow: Biopsy and Histology

Exam: Weakness in both upper and lower extremities, right greater than left.

No MeSH data available.