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Multiple Sclerosis

Patterson RAP - MedPix

View Article: MedPix Image - MedPix Case

Affiliation: Uniformed Services University

ABSTRACT

Diagnosis: Multiple Sclerosis

History: 25 y/o woman has left UE weakness and chorea; with sensory loss to her left arm. Rapidly worsening of spasm in the wrist and hand.

Findings: There are multifocal areas of predominately white matter abnormal signal intensity Several lesions are in the corpus callosum, the largest seen in the body of the corpus callosum; with periventricular and periatrial predominance. Several lesions are oriented perpendicular to the corpus callosum (Dawson’s fingers). Similar hyperintense lesions are also seen in the brain stem and spinal cord, best seen on the sagittal images.

Ddx: 1. Cerebral autosomal dominant arteriopathy with subcortical infarct (CADASIL) 2. Lyme disease 3. Central nervous system vasculitis 4. Multiple Sclerosis 5. ADEM (Acute Disseminated Encephalomyelitis

Exam: Physical exam: not available Laboratory:-- 3 oligoclonal bands seen in CSF; no oligoclonal bands present in serum-- serum cardiolipin IgG, IgM, IgA negative-- ds DNA AB positive (28 IU/mL)-- ENA negative-- Lyme AB Total borderline; B. burgdorferi IgG, IgM negative

No MeSH data available.


Multiple areas of abnormal signal intensity - most are in the deep and periventricular white matter
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MPX1952_synpic21353: Multiple areas of abnormal signal intensity - most are in the deep and periventricular white matter


Multiple Sclerosis

Patterson RAP - MedPix

Multiple areas of abnormal signal intensity - most are in the deep and periventricular white matter
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=MPX1952&req=5

MPX1952_synpic21353: Multiple areas of abnormal signal intensity - most are in the deep and periventricular white matter

View Article: MedPix Image - MedPix Case

Affiliation: Uniformed Services University

ABSTRACT

Diagnosis: Multiple Sclerosis

History: 25 y/o woman has left UE weakness and chorea; with sensory loss to her left arm. Rapidly worsening of spasm in the wrist and hand.

Findings: There are multifocal areas of predominately white matter abnormal signal intensity Several lesions are in the corpus callosum, the largest seen in the body of the corpus callosum; with periventricular and periatrial predominance. Several lesions are oriented perpendicular to the corpus callosum (Dawson’s fingers). Similar hyperintense lesions are also seen in the brain stem and spinal cord, best seen on the sagittal images.

Ddx: 1. Cerebral autosomal dominant arteriopathy with subcortical infarct (CADASIL) 2. Lyme disease 3. Central nervous system vasculitis 4. Multiple Sclerosis 5. ADEM (Acute Disseminated Encephalomyelitis

Exam: Physical exam: not available Laboratory:-- 3 oligoclonal bands seen in CSF; no oligoclonal bands present in serum-- serum cardiolipin IgG, IgM, IgA negative-- ds DNA AB positive (28 IU/mL)-- ENA negative-- Lyme AB Total borderline; B. burgdorferi IgG, IgM negative

No MeSH data available.