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Case 5, (27th Annual Uniformed Services Dermatology Seminar, 2003) DERMATOMYOSITIS

Twede JVT - MedPix (2006)

View Article: MedPix Image - MedPix Case

Affiliation: Uniformed Services University

ABSTRACT

Diagnosis: Case 5, (27th Annual Uniformed Services Dermatology Seminar, 2003) DERMATOMYOSITIS

History: History: A 55 year old Caucasian female with a nine year history of dermatomyositis.

Findings: Labs: ANA positive 1:320 speckled; Anti-RNP, Anti-Smith, Anti-Ro/La, Anti-Jo antibodies negative; MRI of lower extremities demonstrated extensive atrophy with minimal inflammation; EMG consistant with myopathic disease; history of slightly elevated CK and aldolase when symptomatic; hepatitis panel negative. Histopathology: The biopsy shows epidermal atrophy with compact orthokeratotic hyperkeratosis, focal vacuolar interface dermatitis, dilated vessels, and an increase in dermal interstitial mucin.

Ddx: • SLE •rosacea •drug eruption

Dxhow: clinicopathologic correlation

Exam: Examination: Scalp: diffuse nonscarring alopecia, erythema and fine scales Face: heliotrope eruption on eyelids Arms: large violacious lichenified plaques in a photo- distrubution Back: diffuse erythematous patch in a shawl-like distribution Hands: erythematous extensor tendon plaques; Gottron's papules over MCP and PIP joints Fingernails: proximal nail folds with dilated and tortuous capillaries with dropout and ragged cuticles Legs: violaceous plaques on knees and extensor thighs

No MeSH data available.


Histopathology: The biopsy shows epidermal atrophy with compact orthokeratotic hyperkeratosis, focal vacuolar interface dermatitis, dilated vessels, and an increase in dermal interstitial mucin.
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MPX1798_synpic23708: Histopathology: The biopsy shows epidermal atrophy with compact orthokeratotic hyperkeratosis, focal vacuolar interface dermatitis, dilated vessels, and an increase in dermal interstitial mucin.


Case 5, (27th Annual Uniformed Services Dermatology Seminar, 2003) DERMATOMYOSITIS

Twede JVT - MedPix (2006)

Histopathology: The biopsy shows epidermal atrophy with compact orthokeratotic hyperkeratosis, focal vacuolar interface dermatitis, dilated vessels, and an increase in dermal interstitial mucin.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=MPX1798&req=5

MPX1798_synpic23708: Histopathology: The biopsy shows epidermal atrophy with compact orthokeratotic hyperkeratosis, focal vacuolar interface dermatitis, dilated vessels, and an increase in dermal interstitial mucin.

View Article: MedPix Image - MedPix Case

Affiliation: Uniformed Services University

ABSTRACT

Diagnosis: Case 5, (27th Annual Uniformed Services Dermatology Seminar, 2003) DERMATOMYOSITIS

History: History: A 55 year old Caucasian female with a nine year history of dermatomyositis.

Findings: Labs: ANA positive 1:320 speckled; Anti-RNP, Anti-Smith, Anti-Ro/La, Anti-Jo antibodies negative; MRI of lower extremities demonstrated extensive atrophy with minimal inflammation; EMG consistant with myopathic disease; history of slightly elevated CK and aldolase when symptomatic; hepatitis panel negative. Histopathology: The biopsy shows epidermal atrophy with compact orthokeratotic hyperkeratosis, focal vacuolar interface dermatitis, dilated vessels, and an increase in dermal interstitial mucin.

Ddx: • SLE •rosacea •drug eruption

Dxhow: clinicopathologic correlation

Exam: Examination: Scalp: diffuse nonscarring alopecia, erythema and fine scales Face: heliotrope eruption on eyelids Arms: large violacious lichenified plaques in a photo- distrubution Back: diffuse erythematous patch in a shawl-like distribution Hands: erythematous extensor tendon plaques; Gottron's papules over MCP and PIP joints Fingernails: proximal nail folds with dilated and tortuous capillaries with dropout and ragged cuticles Legs: violaceous plaques on knees and extensor thighs

No MeSH data available.