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Case 5, (27th Annual Uniformed Services Dermatology Seminar, 2003) DERMATOMYOSITIS
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Affiliation: Uniformed Services University
ABSTRACT
Diagnosis: Case 5, (27th Annual Uniformed Services Dermatology Seminar, 2003) DERMATOMYOSITIS History: History: A 55 year old Caucasian female with a nine year history of dermatomyositis. Findings: Labs: ANA positive 1:320 speckled; Anti-RNP, Anti-Smith, Anti-Ro/La, Anti-Jo antibodies negative; MRI of lower extremities demonstrated extensive atrophy with minimal inflammation; EMG consistant with myopathic disease; history of slightly elevated CK and aldolase when symptomatic; hepatitis panel negative. Histopathology: The biopsy shows epidermal atrophy with compact orthokeratotic hyperkeratosis, focal vacuolar interface dermatitis, dilated vessels, and an increase in dermal interstitial mucin. Ddx: • SLE •rosacea •drug eruption Dxhow: clinicopathologic correlation Exam: Examination: Scalp: diffuse nonscarring alopecia, erythema and fine scales Face: heliotrope eruption on eyelids Arms: large violacious lichenified plaques in a photo- distrubution Back: diffuse erythematous patch in a shawl-like distribution Hands: erythematous extensor tendon plaques; Gottron's papules over MCP and PIP joints Fingernails: proximal nail folds with dilated and tortuous capillaries with dropout and ragged cuticles Legs: violaceous plaques on knees and extensor thighs No MeSH data available. |
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MPX1798_synpic23704: Histopathology: The biopsy shows epidermal atrophy with compact orthokeratotic hyperkeratosis, focal vacuolar interface dermatitis, dilated vessels, and an increase in dermal interstitial mucin. |
View Article: MedPix Image - MedPix Case
Affiliation: Uniformed Services University
Diagnosis: Case 5, (27th Annual Uniformed Services Dermatology Seminar, 2003) DERMATOMYOSITIS
History: History: A 55 year old Caucasian female with a nine year history of dermatomyositis.
Findings: Labs: ANA positive 1:320 speckled; Anti-RNP, Anti-Smith, Anti-Ro/La, Anti-Jo antibodies negative; MRI of lower extremities demonstrated extensive atrophy with minimal inflammation; EMG consistant with myopathic disease; history of slightly elevated CK and aldolase when symptomatic; hepatitis panel negative. Histopathology: The biopsy shows epidermal atrophy with compact orthokeratotic hyperkeratosis, focal vacuolar interface dermatitis, dilated vessels, and an increase in dermal interstitial mucin.
Ddx: • SLE •rosacea •drug eruption
Dxhow: clinicopathologic correlation
Exam: Examination: Scalp: diffuse nonscarring alopecia, erythema and fine scales Face: heliotrope eruption on eyelids Arms: large violacious lichenified plaques in a photo- distrubution Back: diffuse erythematous patch in a shawl-like distribution Hands: erythematous extensor tendon plaques; Gottron's papules over MCP and PIP joints Fingernails: proximal nail folds with dilated and tortuous capillaries with dropout and ragged cuticles Legs: violaceous plaques on knees and extensor thighs
No MeSH data available.
