Low grade B-cell lymphoma MALT type with plasmacytic differentiation
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Affiliation: Uniformed Services University
ABSTRACT
Diagnosis: Low grade B-cell lymphoma MALT type with plasmacytic differentiation History: Persistence of subretinal deposits Body and Head MRI unremarkable LP normal Vitrectomy: scant cells consistent with chronic inflammation. No cytologic atypia or monoclonal B cell population No definite response to systemic steroids Variable visual acuity 20/20-20/40 94 weeks Increasing subretinal fluid Findings: Pathology: - CD20 positive small lymphoid cells and plasmacytic cells - CD3 less frequent, positive in 1/3 of lymphoid cells - CD5, CD10 negative - In Situ Hybridization – monoclonal lambda positive Ddx: Low grade B-cell lymphoma MALT type with plasmacytic differentiation Radiation to eye and orbit No MeSH data available. |
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MPX1780_synpic37245: Histology of a patient with low grade B-cell lymphoma MALT type with plasmacytic differentiation. |
View Article: MedPix Image - MedPix Case
Affiliation: Uniformed Services University
Diagnosis: Low grade B-cell lymphoma MALT type with plasmacytic differentiation
History: Persistence of subretinal deposits Body and Head MRI unremarkable LP normal Vitrectomy: scant cells consistent with chronic inflammation. No cytologic atypia or monoclonal B cell population No definite response to systemic steroids Variable visual acuity 20/20-20/40 94 weeks Increasing subretinal fluid
Findings: Pathology: - CD20 positive small lymphoid cells and plasmacytic cells - CD3 less frequent, positive in 1/3 of lymphoid cells - CD5, CD10 negative - In Situ Hybridization – monoclonal lambda positive
Ddx: Low grade B-cell lymphoma MALT type with plasmacytic differentiation Radiation to eye and orbit
No MeSH data available.