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 | A new species of Andean toad (Bufonidae, Osornophryne) discovered using molecular and morphological data,... | Figure 8: Osteology of hand and foot of Osornophryne simpsoni sp. n. in ventral view; adult male, QCAZ 45899.Bottom Line: Combining a molecular phylogeny and morphological data, we discovered a new species of Osornophryne from the Amazonian slope of the Ecuadorian Andes.Morphologically, the new taxon is distinguished from all others species in Osornophryne by having the Toes IV... | Páez-Moscoso DJ, Guayasamin JM, Yánez-Muñoz M - Zookeys (2011) |
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![The molecular structure of the title compound. Displacement ellipsoids are drawn at the 30% probability level. [Symmetry code: (A) -x+1, y, -z+1/2.]](/imgs/rescaled137/3011804_e-66-m1570-fig1.png) | Diaqua-bis-{2-hy-droxy-5-[(pyridin-2-yl)methyl-idene-amino]-benzoato-κN,N'}nickel(II) dihydrate. | Fap1: The molecular structure of the title compound. Displacement ellipsoids are drawn at the 30% probability level. [Symmetry code: (A) -x+1, y, -z+1/2.]Bottom Line: In the title complex, [Ni(C(13)H(9)N(2)O(3))(2)(H(2)O)(2)]·2H(2)O, the Ni(II) atom, located on a twofold rotation axis, is in a distorted octa-hedral geometry, defined by four N atoms from two 2-hy-droxy-5-[(pyridin-2-yl)methyl-idene-amino]-benzoate ligands... | Zha M, Li X, Bing Y, Luo Z - Acta Crystallogr Sect E Struct Rep Online (2010) |
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 | (Pyridino-15-crown-5-κN,O,O',O'',O''')bis-(thio-cyanato-κN)manganese(II). | Fap1: The molecular structure of (I), with atom labels and 30% probability displacement ellipsoids for non-H atoms.Bottom Line: The title complex, [Mn(NCS)(2)(C(13)H(19)NO(4))] {systematic name: [3,6,9,12-tetra-oxa-18-aza-bicyclo-[12.3.1]octa-cosa-14(18),15,17-triene-κ(5)N,O,O',O'',O''']bis-(thio-cyanato-κN)manganese(I-I)}, was obtained by the reaction of MnCl(2)·4H(2)O and NaSCN... | Li C, Feng Z, Li D, Wang D - Acta Crystallogr Sect E Struct Rep Online (2008) |
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 | r-2,c-6-Bis(4-chloro-phen-yl)-t-3-isopropyl-1-nitro-sopiperidin-4-one. | Fap2: The packing of (I), viewed along the c axis. Dashed lines indicate hydrogen bonds. H atoms not involved in hydrogen bonding have been omitted.Bottom Line: The two benzene rings and the isopropyl group attached to the piperidine ring in positions 2, 6 and 3, respectively, have axial orientations.The dihedral angle between the two benzene rings is 21.56 (13)°.One of the Cl atoms is disordered over two positions... | Gayathri P, Thiruvalluvar A, Manimekalai A, et al. - Acta Crystallogr Sect E Struct Rep Online (2008) |
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 | 2-(4-Methyl-2-phenyl-piperazin-4-ium-1-yl)pyridine-3-carboxyl-ate dihydrate. | Fap1: The molecular structure of the title compound, drawn with 30% probability ellipsoids.Bottom Line: The title compound, C(17)H(19)N(3)O(2)·2H(2)O, is particularly useful in the preparation of mirtaza-pine, which is the active agent in a new class of anti-depressants.It crystallized as a zwitterion with two mol-ecules of water in the asymmetric unit.The crystal... | Li AJ, Zhang XH, Sun WQ, Zhou XQ, Liu DZ - Acta Crystallogr Sect E Struct Rep Online (2008) |
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 | Coaggregation of FcepsilonRI with FcgammaRIIB Inhibits Degranulation but Not Induction of Bcl-2 Family... | Figure 6: Schematic diagram showing the effect of coengagement of FcεRI with FcγRIIB. Coaggregation of FcεRI with FcγRIIB inhibits degranulation but not the induction of Bim and A1.Bottom Line: Coaggregation led to an attenuation of Akt phosphorylation but did not inhibit phosphorylation of transcription factor Foxo3a or its proapoptotic target, Bim.Similarly, FcepsilonRI-dependent expression of the prosurvival gene A1 was not affected by coaggregation.Our... | Ekoff M, Möller C, Xiang Z, Nilsson G - Allergy Asthma Clin Immunol (2006) |
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![A section of the structure of the title compound, showing the atomic numbering scheme with 30% probability displacement ellipsoids. [Symmetry codes: (i) 1-x, 1-y, 1-z. (ii)y, x-1, z. (iii) 2-x, 1-y,2-z.]](/imgs/rescaled137/2979272_e-66-0m511-fig1.png) | Poly[μ(2)-aqua-aqua-(μ(3)-1H-benzimidazole-5,6-dicarboxyl-ato-κN:O:O)manganese(II)]. | Fap1: A section of the structure of the title compound, showing the atomic numbering scheme with 30% probability displacement ellipsoids. [Symmetry codes: (i) 1-x, 1-y, 1-z. (ii)y, x-1, z. (iii) 2-x, 1-y,2-z.]Bottom Line: In the title complex, [Mn(C(9)H(4)N(2)O(4))(H(2)O)(2)](n), the Mn(II) atom is in a distorted octa-hedral coordination completed by one N atom from one 1H-benzimidazole-5,6-dicarboxyl-ate ligand, two O atoms from two different 1H-benzimidazole-5,6-dicarboxyl-ate... | Zheng-De T, Qian-Qian H, Bing Y - Acta Crystallogr Sect E Struct Rep Online (2010) |
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 | catena-Poly[[diaqua-nickel(II)]-μ-7-oxabicyclo-[2.2.1]heptane-2,3-di-carboxyl-ato]. | Fap1: A view of the molecule of (I) showing the atom-labelling scheme with displacement ellipsoids drawn at the 30% probability.Bottom Line: In the crystal structure of the title compound, [Ni(C(8)H(8)O(5))(H(2)O)(2)](n), the Ni(II) cation is in a Jahn-Teller-distorted octahedral coordination environment binding to two O atoms from water molecules, the bridging O atom of the bicycloheptane unit,... | Wang YY, Hu RD, Zhu WZ, Lin QY - Acta Crystallogr Sect E Struct Rep Online (2009) |
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 | {2,2'-[(5-Bromo-pyridine-2,3-di-yl)bis-(nitrilo-methyl-idyne)]diphenolato}chlorido(N,N-dimethyl-formamide)iron(III). | Fap1: The molecular structure of (I) showing the atom-labelling scheme. Displacement ellipsoids are drawn at the 30% probability level. Hydrogen atoms have been omitted for clarity.Bottom Line: In the title complex, [Fe(C(19)H(12)BrClN(3)O(2))(C(3)H(7)NO)], the Fe(III) atom is coordinated by an N,N,O,O-tetra-dentate Schiff base ligand and trans coordinated by a chloride anion and the O atom of an N,N-dimethyl-formamide mol-ecule.The resulting geometry... | Sheng N, Ni Z - Acta Crystallogr Sect E Struct Rep Online (2009) |
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 | 9-(4-Fluoro-phen-yl)-3,3,6,6-tetra-methyl-10-p-tolyl-1,2,3,4,5,6,7,8,9,10-deca-hydroacridine-1,8-dione. | Fap1: The molecular structure of the title molecule, with the atom-numbering scheme. Displacement ellipsoids are drawn at the 30% probability level.Bottom Line: The title compound, C(30)H(32)FNO(2), was synthesized by the reaction of dimedone with 4-fluoro-benzaldehyde and p-toluidine in water.The dihydro-pyridine and both of the cyclo-hexenone rings are not planar and have flattened boat conformations.The dihedral... | Tang Z, Liu C, Wu S, Hao W - Acta Crystallogr Sect E Struct Rep Online (2008) |
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 | 2-Amino-4-tert-butyl-5-(4-chloro-benz-yl)thia-zol-3-ium chloride. | Fap1: The structure of the title compound showing 50% probability displacement ellipsoids.Bottom Line: The title compound, C(14)H(18)ClN(2)S(+)·Cl(-), crystallizes with two formula units in the asymmetric unit.The dihedral angles between the mean planes of the chloro-phenyl and thia-zole rings are 87.8 (2) and 88.0 (2)° in the two independent mol-ecules.In... | Peng JM, Yang LT, Qin Z, Hu AX - Acta Crystallogr Sect E Struct Rep Online (2010) |
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![Schematic depiction of the procyclin loci in AnTat 1.1 and lineage of the knockouts [15].GPEET2 is a variant that has 5 rather than 6 copies of the pentapeptide repeat. Deletion constructs containing antibiotic-resistance genes were designed to delete tandemly linked procyclin genes by homologous recombination (see Materials and Methods). In the addback Δproc/EP2+, the neomycin-resistance gene was replaced by EP2 procyclin and the blasticidin resistance gene. The truncated 3′ UTR (ΔLII) downstream of EP2 ensures high levels of expression in procyclic forms [36], [40]. B: bloodstream form; P: procyclic form. Arrowhead: transmitted through tsetse and mice.](/imgs/rescaled137/2637416_pone.0004493.g001.png) | Major surface glycoproteins of insect forms of Trypanosoma brucei are not essential for cyclical transmission... | pone-0004493-g001: Schematic depiction of the procyclin loci in AnTat 1.1 and lineage of the knockouts [15].GPEET2 is a variant that has 5 rather than 6 copies of the pentapeptide repeat. Deletion constructs containing antibiotic-resistance genes were designed to delete tandemly...Bottom Line: To determine if procyclins are essential for survival and transmission of T. brucei, all four genes were deleted and parasite fitness was compared in vitro and in vivo.In contrast, when flies were infected with the same mixture, the mutant was rapidly overgrown... | Vassella E, Oberle M, Urwyler S, Renggli CK, et al. - PLoS ONE (2009) |
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 | 1-Benzoyl-3,5-diphenyl-4,5-dihydro-1H-pyrazole. | Fap1: The molecular structure of the title compound, showing displacement ellipsoids drawn at the 30% probability level. H atoms have been omitted for clarity.Bottom Line: In the title compound, C(22)H(18)N(2)O, the pyrazole ring is almost planar (r.m.s. deviation = 0.0098 Å) and its mean plane makes dihedral angles of 62.2 (2), 87.2 (2) and 8.0 (2)° with the phenyl and benzoyl rings, respectively.The crystal packing... | Zheng CZ, Wang L, Liu J - Acta Crystallogr Sect E Struct Rep Online (2011) |
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 | Characteristics of metal enhanced evanescent-wave microcavities. | f2-sensors-10-08751: Schematic of the experimental setup for the excitations of enhanced evanescent fields in the microcavity and for successively changing the air-gap distance between two metals.Bottom Line: Numerical simulations show that the reflected light depends remarkably upon distributions of the enhanced electric fields in the air-gap at the optical mode excitations.The metallic microcavities have a Q value on the order of 10(2), as determined from calculations.Experimentally,... | Wakamatsu T - Sensors (Basel) (2010) |
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 | Gene expression profiling reveals effects of Cimicifuga racemosa (L.) NUTT. (black cohosh) on the estrogen... | Figure 7: Overlap of expression profiles. Numbers within the 3 circles represent the genes that were differentially expressed according to our filters after 24 h treatment of MCF-7 cells with Cimicifuga racemosa (black cohosh) extract (CR), 17β-estradiol (E2) or tamoxifen...Bottom Line: Also several transcripts coding for oxidoreductases were induced, as for example the cytochrome P450 family members 1A1 and 1B1.In addition, some transcripts associated with antitumor but also tumor-promoting activity were regulated.The effects may be results... | Gaube F, Wolfl S, Pusch L, Kroll TC, Hamburger M - BMC Pharmacol. (2007) |
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 | {Bis[2-(dicyclo-hexyl-phosphino)phen-yl]methyl-silyl-κP,Si,P'}chloridoplatinum(II). | Fap1: Molecular structure of the title compound. Displacement ellipsoids are drawn at the 30% probability level. H atoms have been omitted for clarity.Bottom Line: In the title compound, [Pt(C(37)H(55)P(2)Si)Cl], prepared from MeSiH[(cy)(2)PC(6)H(4)](2) and [Pt(cod)Cl(2)] (cy = cyclo-hexyl; cod = cyclo-octa-1,5-diene), the Pt(II) atom is coordinated by two P atoms, one Si atom and one Cl atom in a distorted square-planar... | Li YH, Zhang Y, Zhao MM, Li X - Acta Crystallogr Sect E Struct Rep Online (2008) |
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 | Chlorido{N,N'-o-phenyl-ene-[6,6'-ethyl-enebis(pyridine-2-carboxamide)]}iron(III). | Fap1: The molecular structure of the title compound. Displacement ellipsoids are drawn at the 30% probability level.Bottom Line: In the title compound, [Fe(C(20)H(14)N(4)O(2))Cl], the Fe(III) ion is in a distorted square-pyramidal environment, with two pyridine and two deprotonated amide N atoms in the basal plane and the Cl ion in the apical position.The Fe(III) ion is displaced from... | Yang L, Tang B - Acta Crystallogr Sect E Struct Rep Online (2008) |
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 | Chlorido(2-imino-methyl-3-fluoro-phenyl-κC,N)tris-(trimethyl-phos-phane-κP)iron. | Fap1: A view of the structure of (I), showing the atomic numbering scheme and 30% probability displacement ellipsoids.Bottom Line: The title compound, [Fe(C(7)H(5)FN)Cl(C(3)H(9)P)(3)], was obtained as a product of the reaction of [Fe(Me(3)P)(4)] with a molar equivalent of (2-chloro-6-fluoro-phen-yl)methanimine in diethyl ether.The Fe atom has an octa-hedral coordination geometry in which... | Xu X, Li X - Acta Crystallogr Sect E Struct Rep Online (2011) |
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 | 5-(4-Bromo-phen-yl)-1,2,3,4-tetra-hydro-benzo[a]phenanthridine. | Fap1: The molecular structure drawing for (I) showing 50% probability of displacement ellipsoids.Bottom Line: The title compound, C(23)H(18)BrN, was synthesized by the reaction of 4-bromo-benzaldehyde, naphthalen-2-amine and cyclo-hexa-none in tetra-hydro-furan, catalyzed by iodine.The saturated six-membered ring adopts a half-chair conformation, and the four vicinal... | Xie HS, Zhang AL, Su L - Acta Crystallogr Sect E Struct Rep Online (2009) |
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