Open-i Logo
Submit this form Query By Image

Internet Explorer requires you to use Upload Image button. Other browsers support the ability to drag and drop the image to anywhere in the browser window to perform an Image Search or use the Upload Image button.

Supported File Types are: .jpeg, .jpg, .gif and .png.
Results 1 - 20 of 545382 1 2 3 4 5 Next View as List View Image Grid View

- Selected Limits -

Query By Image

Similar Collection Image

Rank By

Image Type

Subsets

Specialties

Search In
Probability of survival for CS 4, CS 4+ and CS 5.Probability of survival for the 3 different endpoints (CS 4, black line; CS 4+, blue line; CS 5, red line). For all logrank tests, CS 4 was used as the reference when comparing CS 4 vs. CS 4+ and CS 4 vs. CS 5, whereas CS 4+ was used as the reference when comparing CS 4+ vs. CS 5. The rate of reaching endpoint is significantly different (P = 0.021) between CS 4 (clinical score of 4 = functional paralysis of both hindlimbs), CS 4+ [CS 4 plus the earliest of a) weight loss ≥20% vs. body weight immediately prior to a clinical score of 2, b) weight loss ≥20% vs. peak body weight, c) body condition score <2, or d) a righting reflex >20 s (CS 5)], and CS 5 (clinical score of 5 = CS 4 and righting reflex >20 s). Mice reached CS 4 at a rate of 34% faster vs. CS 5 (HR = 1.34; 95% CI 1.10, 1.74; P = 0.006) and 24% faster vs. CS 4+ (HR = 1.24; 95% CI 1.00, 1.59; P = 0.046). Mice reached CS 4+ at a non-significant rate of 9% faster vs. CS 5 (HR = 1.09; 95% CI 0.88, 1.38; P = 0.410). Comparative analysis between different treatment regimens.Comparison of biological response of Avonex treated patients and Betaferon or Rebif treated patients. A. Average biological response using the set of 15 IFN-induced genes in the test group of 16 RRMS patients; B. Biological response using PCR based gene expression levels for RSAD2 in the second independent validation group of 30 RRMS patients. Inhibition by anti– Nr-CAM antibodies of neurite extension induced by βCFS. Primary chick tectal cells were plated on dishes coated with βCFS fusion protein (80 μg/ml) and cultured for 48 h in the presence of Fab′ fragments (500 μg/ml) of nonimmune (A) or anti– Nr-CAM polyclonal antibody (B). The plates were fixed and photographed. Quantification of lengths of tectal cell neurites on βCFS fusion protein (C) and on Ng-CAM (D) in the presence of Fab′ fragments. The average neurite lengths on βCFS (C) treated with Fab′ were 59 ± 4 μm (n = 193) for normal rabbit, 55 ± 2 μm (n = 302) for anti–Ng-CAM, and 16 ± 3 μm (n = 93) for anti–NrCAM. The average neurite lengths on Ng-CAM (D) treated with Fab′ were 83 ± 5 μm (n = 198) for normal rabbit, 34 ± 2 μm (n = 118) for anti–Ng-CAM, and 80 ± 5 μm (n = 187) for anti–Nr-CAM. The percentage of neurons with neurites longer than a given length in micrometers was determined as described in Materials and Methods. The results of one representative experiment are shown, and similar results were obtained in five different experiments. Anti–Nr-CAM polyclonal antibody, inhibited neurite outgrowth on Nr-CAM substrate completely at the concentration of 500 μg/ml (data not shown). Bar, 100 μm. Scatter plot showing the median and interquartile C3a levels in children with severe malaria anaemia (cases) and those with uncomplicated malaria (controls). The median values were significantly higher in the controls (3,500 ng/ml, 3,100–4,200) compared to the cases (3,200 ng/mL, 2,800–3,700) P = 0.02). Wilcoxon matched-pairs signed-ranks test was performed with the 43 paired samples. Inhibition of disintegration as a function of increasing MK-2048 concentration. Subtype B and C disintegration activity (presented as relative percentage) in reaction to increasing MK-2048 concentration. This graph was prepared with GraphPad Prism 4.0, the combined result of quantification and analyses of 3 independent experiments.
Inhibition of 17-AAG-induced beta-lactamase reporter activity in the HSE-bla HeLa cells. Cells were pretreated with the indicated concentrations of quercetin and then stimulated with 65 nM 17-AAG for 5 hours before the beta-lactamase assay was performed as described in Methods. Response Ratios were plotted for the indicated concentrations of quercetin (n=4 for each data point). The calculated IC50 for quercetin was 5.8 µM. Fractional renal clearance of L-FABP in patients undergoing liver resection (n = 10). From the fractional renal extraction of FABPs (approximately 30%) and renal blood flow (22% of total blood volume per minute) [12], a plasma half-life of FABPs of 11 min can be calculated. [A] = arterial concentration, [RV] = renal venous concentration Scatter plots of PSA and MIF in random serum samples obtained following routine PSA testing. Median values for each group are represented by horizontal lines. Diagnosis of prostate cancer was determined by chart review. *** = p < 0.001 A) Serum MIF – All data points were mean values of duplicate ELISA analyses. B) Serum PSA – All data were obtained from computerized records of clinical laboratory analysis. OVA257–264-coated B cells induce OVA-specific CTL tolerance in B6 mice. B6 mice were injected intravenously with 107 OVA257–264-coated B6 B cells, unpulsed B6 B cells, or medium alone, and rechallenged 7 d later with (a and c) 25 × 106 OVA-loaded spleen cells injected intravenously or (b) 10 μg OVA257–264 in CFA injected subcutaneously. After an additional 7 d, their spleens were removed and stimulated in vitro for 6 d before a 4-h chromium release assay was performed. (a and b) Percent specific lysis of 51Cr-labeled OVA257–264-coated EL4 (filled symbols) and EL4 (open symbols) in mice injected with B cells coated with OVA257–264 at 10 μg/ml (squares) or with medium alone (circles). (c) The number of OVA-specific LU/spleen for individual mice (filled triangles) treated as in a, and calculated as described in Materials and Methods. OVAp, OVA257–264 coated. Open circles, average LU/spleen for each group. TECK blocks the binding of mAb 3C3 to GPR-9-6 on transfectants and lymphocytes. (A) L1.2/GPR-9-6 transfectants were preincubated with various concentrations of TECK or MDC on ice in PBS with 5% FCS, 10% human serum, and 0.2% azide for 10 min before the addition of mAb 3C3. (B) Mononuclear cells were treated in a similar manner but with either 500 nM MDC or 500 nM TECK. Cells were then stained as described in Materials and Methods (n = 2).
The modulation depth of the micro-heater ranging from frequency of 0∼100 Hz. Part of the polymeric structure of the title compound, showing 30% probability displacement ellipsoids and the atom-numbering scheme. The H atoms are omitted for clarity. The suffix A corresponds to symmetry code (2 - x, 1 - y, 1 - z). Distribution of large intestinal disease mediated by Th1 and Th2 cells. The large intestines of pnir15.OVA-E. coli-colonized RAG-2−/− mice reconstituted with naive, Th1, or Th2 DO11.RAG-2−/− cells were subdivided into the indicated anatomical regions and evaluated histologically for disease involvement as in Table I. Illustrative deformation of the sensing structure subject to a downward acceleration. Correlation Analysis between the Maximum Number of Cell Types and the Density of the Transmembrane Gene Duplicates throughout the History of LifeThe estimates of the number of cell types in eukaryotes at different times in the past was derived from the work of Hedges et al. [23], and the corresponding density of duplicates was calculated by using linear interpolation in the time series inferred from the overall density trace (for details, see Protocol S1).
Displacement of 3H-naloxone by both (-) and (+)-naloxone in BV2 microglia. BV2 microglia (2 × 106) were used for binding experiments. Cells were incubated with hot and indicated fold concentrations of cold naloxone in binding buffer (HBSS + 10% serum) for 2 hours at 4°C. Afterward, the medium was removed and cells or membrane were washed seven times with ice-cold HBSS. Cells were lysed with 400 μl of 1 N NaOH. Cell lysate or membrane was mixed with 10 ml of Ultima Gold scintillation fluid and counted for radioactivity. Results are expressed as percentage of total binding observed with hot naloxone alone and are mean ± SEM of three independent experiments performed in duplicate. **P < 0.01 compared with the corresponding control group, ##P < 0.01 compared with SOD group. HBSS, hank Mutation timing and numbers with respect to invasiveness. If invasion or metastasis depends on mutations acquired after transformation, clinically higher stage cancers would be expected to require more time and mutations. However, if an invasive phenotype depends on mutations acquired before transformation, cancers of different clinical stages could require similar numbers of oncogenic mutations and times for progression. The molecular structure of [Mg(AlH4)2(C4H8O)4], showing 50% probability displacement ellipsoids and the atomic numbering scheme. Atoms labelled with the suffix A are generated by the symmetry operation (-x, 1/2-y, z). Cumulative probability plots of individual 1-year radiographic progression scores in 135 rheumatoid arthritis patients who were participating in the Combinatietherapie Bij Reumatoide Artritis (COBRA) trial (67 patients in the monotherapy group (circles) and 68 patients in the combination therapy group (triangles)). Reprinted from [14] with permission of John Wiley & Sons, Inc. (A and B) Effect of V12Rac-1 upon NFATC1-GFP nuclear accumulation in RBL2H3 mast cells. RBL2H3 cells were transfected with 8 μg NFATC1-GFP reporter alone or in combination with 20 μg pEF-V12Rac-1. Cells were recovered for 6 h on glass coverslips before IgE priming and stimulation for 30 min with the indicated concentrations of KLH-DNP (A) or stimulation with 500 ng/ml KLH-DNP for the indicated times (B). Cells were fixed, mounted, and scored for predominant localization of GFP as described. (C) Effect of V12Rac-1 on NFATC1-GFP nuclear export in RBL2H3 mast cells. RBL2H3 cells were transfected with 8 μg NFATC1-GFP reporter alone or in combination with 20 μg pEF-V12Rac-1. Cells were recovered for 6 h on glass coverslips before stimulation for 30 min with 500 ng/ml Ionomycin to induce nuclear uptake of NFATC1-GFP. The medium was then exchanged twice with warm DMEM/10% FCS before addition of 50 nM CsA to prevent further import. At the indicated time points after CsA addition, cells were fixed, mounted, and scored for predominant localization of GFP as described.
Lister Hill National Center for Biomedical Communications
U.S. National Library of Medicine, 8600 Rockville Pike, Bethesda, MD 20894
National Institutes of Health, Department of Health & Human Services
Privacy, Accessibility, Frequently Asked Questions, Contact Us, Collection
Freedom of Information Act, USA.gov