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Cumulative number of coding mutations, cis-regulatory mutations and other types of mutations (gene amplification, gene loss, etc.) that have been identified over time as responsible for phenotypic evolution. Results are from data in Appendix 1. Note that the slope for cis-regulatory mutations has increased in recent years. The current discovery rate of cis-regulatory mutations approximately equals the discovery rate of coding mutations. If this reflects the long-term trend, then we expect ultimately to observe approximately equal numbers of cis-regulatory and coding mutations. The molecular structure of the title compound with displacement ellipsoids at the 30% probability level. Proliferation of CD4-deficient T cells after in vivo depletion of CD4-expressing cells. (A) dLck-hcre3778 Cd4lox/− mice were injected four times with 500 μg each of cytotoxic anti-CD4 antibody on days 0, 1, 2, and 6, while being fed BrdUrd continuously in their drinking water. The FACS® plots show the extent of in vivo CD4 depletion after 7 d. (B) Accumulation of BrdUrd-labeled CD4+ and CD4-deficient cells in anti-CD4–treated and untreated Cd4lox/− dLck-hcre3778 transgenic mice and nontransgenic controls. Rate of cell-cell movement of TEV-GUS in inoculated leaves of B149 and C24.Leaves from plants inoculated with TEV-GUS were harvested at time points indicated and infiltrated with the colorimetric substrate X-gluc. Foci diameter were measured microscopically at time points indicated and represented as mean (±SD). Data at 24 h represent mean of 17 foci, other points represent mean of 39 foci. Carriers of APOC3 variant alleles (-482T, -455C or both) were compared with homozygous for the wild-type alleles at both SNPs (-482C and -455T alleles) for glucose and insulin measurements during oral glucose tolerance test (OGTT). The study cohort underwent OGTT (75 g) test and glucose and insulin were measured baseline (0) and at 30, 60, 90 and 120 min after the administration of glucose. (A) Median glucose and (B) insulin in individuals stratified by the genotypes. No statistical differences were found in either insulin or glucose at different time points in the two groups. P-values were calculated by linear regression (all P-values = NS), including age, gender and body mass index (BMI) as covariates in the model.
Current generation (mA) vs Time (Hours) of Co-culture continuous experiment. Circle: G. sulfurreducens, Square: P. aeruginosa, Upright triangle: S. oneidensis, Upsidedown triangle: E. faecium and Diamond: C. acetobutylicum Reduction in footpad CFU counts with various treatment regimens.Mean CFU count from mouse footpads on the day after infection (Day1), the day of treatment initiation (D11), and after four weeks of: UT = no treatment, CLR = clarithromycin, RIF = rifampin, STR = streptomycin, RPT = rifapentine, The number of asterisks below the x-axis indicates the number of mice with negative footpad cultures. Correlation between IgG antibody reactivity to MSP-2 type A and B antigens. Dashed lines indicate cut-off values for sero-positivity, while solid lines indicate cut-off values for high levels of antibodies. Pairwise correlation coefficient was 0·67, P < 0·001 (n = 146). Structures of DAC compounds Warning: getimagesize(/openi/ssd/prod/wwwroot/current/imgs/rescaled137/2174240_JCB9910012.f6.png): failed to open stream: No such file or directory in /openi/ssd/prod/wwwroot/wwwroot-v1.3.1-2013-04-01/searchresults.php on line 174 Quantitative analysis of cell behavior after injection of the Zyx16-30 peptide. The change in position of the cell edge relative to its original position before injection is shown for representative individual cells injected with the Zyx16-30 peptide (closed squares), the scrambled version of the peptide (open squares), Zyx16-30 peptide preincubated with α-actinin (triangles), and cells injected with the Zyx16-30 peptide in the presence of 10 mM diacetyl monoxime (open circles). The average rate of cell edge retraction upon injection of the Zyx16-30 peptide was determined to be 2.7 microns/min.
Relationship between temporal (between-month) variability (CV) of parasitism rate and temporal variability (CV) of parasite species richness (F1,13 = 64.27, r2 = 0.82, P < 0.0001)
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