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 | Endoplasmic reticulum stress modulates the response of myelinating oligodendrocytes to the immune cytokine... | fig4: Double transgenic mice with a PERK+/− background develop severe hypomyelination. (A and C) MBP immunostaining in the spinal cord of 14-d-old double transgenic mice that received doxycycline (A) or were released from doxycycline at E 14 (C). (B and D) MBP...Bottom Line: We found that apoptosis induced by IFN-gamma in cultured rat oligodendrocytes was associated with endoplasmic reticulum (ER) stress.Compared with a wild-type genetic background, the enforced expression of IFN-gamma in mice that were heterozygous for a loss... | Lin W, Harding HP, Ron D, Popko B - J. Cell Biol. (2005) |
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 | Pre-clinical efficacy and safety of experimental vaccines based on non-replicating vaccinia vectors against... | pone-0024505-g002: Double Immunostaining of infected chicken cells (DF-1).MVA-YF (A), wild-type MVA (B) and MVA-YF/MVA spike control (C). After 4 days infected cells were fixed, incubated with guinea pig anti YFV-17D antiserum and anti-guinea pig IgG conjugated to peroxidase....Bottom Line: Although, a good safety profile was historically attributed to the 17D vaccine, serious adverse events have been reported, making the development of a safer, more modern vaccine desirable.A gene encoding the precursor of the membrane and envelope (prME) protein... | Schäfer B, Holzer GW, Joachimsthaler A, Coulibaly S, et al. - PLoS ONE (2011) |
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 | Pattern of expression of c-erbB-2 oncoprotein in human fetuses. |  Bottom Line: The pattern of expression of the c-erbB-2 oncoprotein was investigated in whole mount preparations of 11 human fetuses by immunocytochemistry using two polyclonal antibodies, 20N and 21N. c-erbB-2 was widely expressed within all three germ layers.Expression... | Quirke P, Pickles A, Tuzi NL, Mohamdee O, et al. - Br. J. Cancer (1989) |
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 | Laparoscopic surgery in infants with intra-abdominal cysts: two case reports. | Figure 2: Through a minimal incision, the cyst was extracted while aspirating the contents using an aspirator.Bottom Line: Oral intake was commenced on postoperative day 2 in both patients.The cosmetic results following LAS were excellent.We conclude that LAS is suitable for the management of omental cystic lesions with torsion and ovarian cyst in nursing infants.An aspirator is... | Kuga T, Inoue T, Taniguchi S, Zempo N, Esato K - JSLS (2000 Jul-Sep) |
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 | Polyurethane sheet: a potential substitute of surgical cotton gauze. | Figure 1: (a) An unused surgical cotton gauze (left), unused polyurethane sheet (center), and polyurethane sheet subjected to the blood-soak and water-rinse procedure 10 times (right). Note that the polyurethane sheet retains sufficient whiteness even after repeated...Bottom Line: Polyurethane sheet is a pure white, soft, and flexible synthetic sponge with a mechanical strength and abrasion resistance equivalent or even superior to other sponge materials.Our study indicates that the blood absorption power of the polyurethane sheet is... | Shimamoto T - J Cardiothorac Surg (2011) |
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 | Tissue adhesives in otorhinolaryngology. | Figure 4: Gelatine resorcinol glutaraldehyde glue (Gluetiss®)Bottom Line: This is caused by the specific demands which are made on a tissue adhesive, and the different areas of application.In otorhinolaryngology, on the one hand, this is the mucosal environment as well as the application on bones, cartilage and periphery nerves.On... | Schneider G - GMS Curr Top Otorhinolaryngol Head Neck Surg (2011) |
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 | Overexpression, purification, crystallization and data collection of Sulfolobus solfataricus Sso6206,... | fig3: Diffraction pattern of Sso6206 collected at the ESRF.Bottom Line: The protein crystallizes in space group P6(1/5)22, with unit-cell parameters a = b = 157.8, c = 307.3 A.Molecular replacement cannot be attempted as no convincing model can be identified.Crystals of selenomethionine-variant protein have not yet been obtained. | McEwan AR, Liu H, Oke M, Carter L, Powers H, et al. - Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. (2006) |
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 | Steindler flexorplasty to restore elbow flexion in C5-C6-C7 brachial plexus palsy type. | Figure 1: Wrist arthrodesis performed with the single-intramedullary-rod technique.Bottom Line: Data were collected from medical records and from the information obtained during follow-up visits.Age, sex, preoperative strength (rated on a 0 to 5 scale for the flexors of the elbow, wrist flexors, pronator and triceps), previous surgery, length of follow-up,... | Monreal R - J Brachial Plex Peripher Nerve Inj (2007) |
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 | Allocentric and egocentric reference frames in the processing of three-dimensional haptic space. | Fig4: A close-up of the bar used in the experiment with the half protractor on the bottom of the bar indicating the tilt (θ) and with the protractor at the base of the pole indicating the slant (φ)Bottom Line: A weighted average model that identifies the origin of the systematic error patterns in the biasing influence of an egocentric reference frame on the allocentric reference frame was proposed as an explanation of the results.First, systematic error patterns... | Volcic R, Kappers AM - Exp Brain Res (2008) |
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 | Oviposition behaviour of four ant parasitoids (Hymenoptera, Braconidae, Euphorinae, Neoneurini and Ichneumonidae,... | Figure 34: Female of Hybrizon buccatus (left) hovering over a permanent vertical trail established between two nest entrances of a colony of Lasius grandis (right).Bottom Line: Two of the observed species (Neoneurus vesculussp. n. and Kollasmosoma sentumsp. n.) are new to science.A third species (Neoneurus recticalcarsp. n.) is described from Slovakia and Norway.Keys to the Palaearctic species of the genera Neoneurus and Kollasmosoma... | Gómez Durán JM, van Achterberg C - Zookeys (2011) |
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 | POSaM: a fast, flexible, open-source, inkjet oligonucleotide synthesizer and microarrayer. | Figure 4: Photomicrograph of virtual reaction wells on silanized glass. Phosphoramidites and tetrazole dissolved in 1:1 3MP:MGN were printed onto a standard epoxysilane-modified slide surface. The slide was carefully removed from the POSaM instrument and a photomicrograph...Bottom Line: Their rapid acceptance was aided by the release of plans for a pin-spotting microarrayer by researchers at Stanford.Inkjet microarraying is a flexible, complementary technique that allows the synthesis of arrays of any oligonucleotide sequences de novo.We describe... | Lausted C, Dahl T, Warren C, King K, Smith K, et al. - Genome Biol. (2004) |
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 | A Differential Pressure Instrument with Wireless Telemetry for In-Situ Measurement of Fluid Flow across... | f5-sensors-09-00404: An early differential pressure logger ready for deployment. This instrument has not yet been upgraded to include a port for wireless communication.Bottom Line: Key objectives of the design include both low cost, and accuracy of the order of ±0.5 mm H(2)O in measured head difference between the instrument's two pressure ports.These objectives have been met, although a revision to the design of one component was found... | Gardner AT, Karam HN, Mulligan AE, Harvey CF, et al. - Sensors (Basel) (2009) |
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 | Diffeomorphic registration using geodesic shooting and Gauss-Newton optimisation. | f0070: A single slice through the divergence of velocity fields computed after registering one of the LPBA40 subjects. The top row shows results from registering via GS, whereas the bottom row shows results from using Dartel. Results from un-translated data are shown...Bottom Line: Rather than perform a variational optimisation on a series of velocity fields, the algorithm is formulated to use a geodesic shooting procedure, so that only an initial velocity is estimated.A Gauss-Newton optimisation strategy is used to achieve faster convergence.The... | Ashburner J, Friston KJ - Neuroimage (2011) |
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 | Caenorhabditis elegans BAH-1 is a DUF23 protein expressed in seam cells and required for microbial biofilm... | pone-0006741-g001: bah-1 worms are resistant to biofilm attachment.(A–C) Wild-type C. elegans exposed to (A) E. coli, (B) Y. pestis, and (C) Y. pseudotuberculosis. (D–F) bah-1 worms exposed to (D) E. coli, (E) Y. pestis, and (F) Y. pseudotuberculosis.Bottom Line: The cuticle of Caenorhabditis elegans, a complex, multi-layered extracellular matrix, is a major interface between the animal and its environment.A C. elegans gene required for biofilm attachment, bah-1, encodes a protein containing the domain of unknown function... | Drace K, McLaughlin S, Darby C - PLoS ONE (2009) |
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 | Internal plate fixation of fractures: short history and recent developments. | Fig10: Railed plates (left) have limited bone-plate contact area compared to contact plates (right)Bottom Line: Moreover, clinical studies of newer plate types have failed to show a superior outcome.No positive correlation was found between either.Results of ongoing experimental results are encouraging. | Uhthoff HK, Poitras P, Backman DS - J Orthop Sci (2006) |
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 | Diffeomorphic registration using geodesic shooting and Gauss-Newton optimisation. | f0030: The velocity (left panel) and “momentum” (right panel) fields of the four models. The left column shows the horizontal component, whereas the right column shows the vertical component. The top row shows the initial velocities and momenta obtained using...Bottom Line: Rather than perform a variational optimisation on a series of velocity fields, the algorithm is formulated to use a geodesic shooting procedure, so that only an initial velocity is estimated.A Gauss-Newton optimisation strategy is used to achieve faster convergence.The... | Ashburner J, Friston KJ - Neuroimage (2011) |
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 | Coil occlusion of the large patent ductus arteriosus. | Figure 10: Retrieval sequence after embolization into the left pulmonary artery. Two coils were used to close a large duct an infant. These coils embolized as soon as the jaws of the bioptome were opened into the LPA (A). The sutured end of the coils have been grasped...Bottom Line: Coil occlusion has a specific advantage for relatively larger ducts in selected small children and in preterm infants because it is possible to accomplish delivery of multiple coils through relatively small introducer sheaths.In addition, aortic narrowing is... | Kumar R, Nair A - Images Paediatr Cardiol (2008) |
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