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Pulmonary alveolar microlithiasis

Gayathri Devi HJ, Mohan Rao KN, Prathima KM, Das JK - Lung India (2011)

Bottom Line: Pulmonary alveolar microlithiasis is a rare disease of unknown cause.We report a case in a young boy who presented with history of failure to thrive and chest X-ray finding suggestive of miliary mottling.Open lung biopsy revealed pulmonary alveolar microlithiasis.

Affiliation: Department of Chest Diseases, MS Ramaiah Medical College, Bangalore, India.

ABSTRACT

Pulmonary alveolar microlithiasis is a rare disease of unknown cause. We report a case in a young boy who presented with history of failure to thrive and chest X-ray finding suggestive of miliary mottling. Open lung biopsy revealed pulmonary alveolar microlithiasis.

Chest X-ray showing bilateral diffuse high density micronodular opacities more toward the mid and lower zones
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Figure 0001: Chest X-ray showing bilateral diffuse high density micronodular opacities more toward the mid and lower zones

Mentions: His CBC, electrolytes and calcium were normal. Ultrasound of abdomen was normal. Flow volume loop showed mild restriction. Serial chest X-rays from 2007 showed bilateral diffuse micronodular calcific shadows more toward the mid and lower zones [Figures 1 and 2]. HRCT scan showed bilateral diffuse micronodular opacities distributed predominantly over basal and posterior regions with thickening of interlobar septa [Figure 3]. Wedge biopsy of the Lingula was done. Histopathology examination revealed multiple calcispherites within the alveoli of lung parenchyma suggestive of pulmonary alveolar microlithiasis of lung [Figure 4]. Chest X-ray of his only sibling did not reveal any abnormality.

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Pulmonary alveolar microlithiasis

Gayathri Devi HJ, Mohan Rao KN, Prathima KM, Das JK - Lung India (2011)

Chest X-ray showing bilateral diffuse high density micronodular opacities more toward the mid and lower zones
© Copyright Policy - open-access
Figure 0001: Chest X-ray showing bilateral diffuse high density micronodular opacities more toward the mid and lower zones
Mentions: His CBC, electrolytes and calcium were normal. Ultrasound of abdomen was normal. Flow volume loop showed mild restriction. Serial chest X-rays from 2007 showed bilateral diffuse micronodular calcific shadows more toward the mid and lower zones [Figures 1 and 2]. HRCT scan showed bilateral diffuse micronodular opacities distributed predominantly over basal and posterior regions with thickening of interlobar septa [Figure 3]. Wedge biopsy of the Lingula was done. Histopathology examination revealed multiple calcispherites within the alveoli of lung parenchyma suggestive of pulmonary alveolar microlithiasis of lung [Figure 4]. Chest X-ray of his only sibling did not reveal any abnormality.

Bottom Line: Pulmonary alveolar microlithiasis is a rare disease of unknown cause.We report a case in a young boy who presented with history of failure to thrive and chest X-ray finding suggestive of miliary mottling.Open lung biopsy revealed pulmonary alveolar microlithiasis.

Affiliation: Department of Chest Diseases, MS Ramaiah Medical College, Bangalore, India.

ABSTRACT

Pulmonary alveolar microlithiasis is a rare disease of unknown cause. We report a case in a young boy who presented with history of failure to thrive and chest X-ray finding suggestive of miliary mottling. Open lung biopsy revealed pulmonary alveolar microlithiasis.

View Similar Images In: Results  - Collection
View Article: PubMed Central -  PubMed
Show All Figures - Show MeSH
getmorefigures.php?pmc=3109840&rFormat=json&query=null&req=5